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Jaundice in Urinary Tract Infection in Infancy

Jaundice in Urinary Tract Infection in Infancy Abstract ATTENTION has recently been directed to the relationship between urinary tract infection and the development of jaundice in young infants.1-6 We have seen 11 infants with this condition over a relatively short time, leading us to the conclusion that such cases are more common than generally believed. Because the presence of jaundice, hepatomegaly, and poor weight gain may lead to the erroneous diagnosis of giant cell hepatitis or biliary atresia, with consequent delay in the institution of urgently required antibiotic therapy, it is important to recognize this syndrome. This report summarizes our experience and reviews the pertinent, recent literature. Report of Cases Eleven bottle-fed infants (ten boys), ranging in age from 8 to 56 days, were admitted to the Cook County Hospital within a period of 11 months (Nov 1, 1967 to Oct 14, 1968) with a history of jaundice, irritability, poor feeding, and lethargy of one to four References 1. Bernstein, J., and Brown, A.K.: Sepsis and Jaundice in Early Infancy , Pediatrics 29:873-882 ( (June) ) 1962. 2. Handel, D., and Kitlak, W.: Jaundice as Chief Symptom of Pyuria During Infancy , Deutsch Med Wschr 91:1781-1785 ( (Oct 7) ) 1966.Crossref 3. Kenny, J.F., et al: An Outbreak of Urinary Tract Infections and Septicemia Due to Escherichia coli in Male Infants , J Pediat 68:530-541 ( (April) ) 1966.Crossref 4. Arthur, A.B., and Wilson, B.D.R.: Urinary Infection Presenting With Jaundice , Brit Med J 1: 539-540 ( (March 4) ) 1967.Crossref 5. Neumann, C.G., and Pryles, C.V.: Pyelonephritis in Infants and Children , Amer J Dis Child 104:215-229 ( (Sept) ) 1962.Crossref 6. Sweet, A.Y., and Wolinsky, E.: An Outbreak of Urinary Tract and Other Infections Due to E coli , Pediatrics 33:865-871 ( (June) ) 1964. 7. Hamilton, J.R., and Sass-Kortsak, A.: Jaundice Associated With Severe Bacterial Infection in Young Infants , J Pediat 63:121-132 ( (July) ) 1963.Crossref 8. Thurman, W.G.: Changes in Red Cell Fragility With Infection , abstracted, Amer J Dis Child 100: 639 ( (Oct) ) 1960. 9. Wheeler, W.: Are There "Pyelopathogenic" E coli? , Pediatrics 33:863-864 ( (June) ) 1964. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Jaundice in Urinary Tract Infection in Infancy

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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1969.02100040555002
Publisher site
See Article on Publisher Site

Abstract

Abstract ATTENTION has recently been directed to the relationship between urinary tract infection and the development of jaundice in young infants.1-6 We have seen 11 infants with this condition over a relatively short time, leading us to the conclusion that such cases are more common than generally believed. Because the presence of jaundice, hepatomegaly, and poor weight gain may lead to the erroneous diagnosis of giant cell hepatitis or biliary atresia, with consequent delay in the institution of urgently required antibiotic therapy, it is important to recognize this syndrome. This report summarizes our experience and reviews the pertinent, recent literature. Report of Cases Eleven bottle-fed infants (ten boys), ranging in age from 8 to 56 days, were admitted to the Cook County Hospital within a period of 11 months (Nov 1, 1967 to Oct 14, 1968) with a history of jaundice, irritability, poor feeding, and lethargy of one to four References 1. Bernstein, J., and Brown, A.K.: Sepsis and Jaundice in Early Infancy , Pediatrics 29:873-882 ( (June) ) 1962. 2. Handel, D., and Kitlak, W.: Jaundice as Chief Symptom of Pyuria During Infancy , Deutsch Med Wschr 91:1781-1785 ( (Oct 7) ) 1966.Crossref 3. Kenny, J.F., et al: An Outbreak of Urinary Tract Infections and Septicemia Due to Escherichia coli in Male Infants , J Pediat 68:530-541 ( (April) ) 1966.Crossref 4. Arthur, A.B., and Wilson, B.D.R.: Urinary Infection Presenting With Jaundice , Brit Med J 1: 539-540 ( (March 4) ) 1967.Crossref 5. Neumann, C.G., and Pryles, C.V.: Pyelonephritis in Infants and Children , Amer J Dis Child 104:215-229 ( (Sept) ) 1962.Crossref 6. Sweet, A.Y., and Wolinsky, E.: An Outbreak of Urinary Tract and Other Infections Due to E coli , Pediatrics 33:865-871 ( (June) ) 1964. 7. Hamilton, J.R., and Sass-Kortsak, A.: Jaundice Associated With Severe Bacterial Infection in Young Infants , J Pediat 63:121-132 ( (July) ) 1963.Crossref 8. Thurman, W.G.: Changes in Red Cell Fragility With Infection , abstracted, Amer J Dis Child 100: 639 ( (Oct) ) 1960. 9. Wheeler, W.: Are There "Pyelopathogenic" E coli? , Pediatrics 33:863-864 ( (June) ) 1964.

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Oct 1, 1969

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