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Encephalitis and Purpura With Influenza Infection: A Case Report

Encephalitis and Purpura With Influenza Infection: A Case Report Abstract THE PROTEAN manifestations of influenza virus infections are well known. Encephalitis and purpura are rare complications of this infection, and our case is presented to document the occurrence of both these unusual findings in a child who was infected with the Asian influenza virus. Report of Case A 12-month-old boy was admitted to the San Francisco General Hospital on April 12, 1963. He had been in good health until three days prior to admission, at which time he developed rhinorrhea, sore throat, and a low-grade fever. On the day before admission his family physician noted congestion of the pharynx and tympanic membranes, and prescribed promethazine (Phenergan) and tetracycline. Several hours before admission the child had "bizarre movements" and could not sit up. Past medical history was noncontributory except for a primary smallpox vaccination 25 days prior to admission (March 18, 1963).On admission this child was irritable, moderately disoriented, with References 1. Bell, W.E.; McKee, A.P.; and Utterback, R.A.: Asian Influenza Virus as the Cause of Acute Encephalitis , Neurology 8:500, 1958.Crossref 2. Mellman, W.J.: Influenza Encephalitis , J Pediat 53: 292, 1958,Crossref 3. Flewett, T.H., and Hoult, J.G.: Influenzal Encephalopathy and Postinfluenzal Encephalitis , Lancet 2:11, 1958.Crossref 4. Dubowitz, V.: Influenzal Encephalitis , Lancet 1:140, 1958.Crossref 5. McConkey, B., and Daws, R.A.: Neurological Disorders Associated With Asian Influenza , Lancet 2:15, 1958.Crossref 6. Dunbar, J.M., et al: Encephalitis and Influenza , Brit Med J 1:913, 1958.Crossref 7. Anderson, W.W., and Jaros, R.M.: Neurologic Complications of Asian Influenza , Neurology 8:562, 1958. 8. Horner, F.A.: Neurologic Disorders After Asian Influenza , New Eng J Med 258:983, 1958.Crossref 9. Jellinger, K., and Seitelberger, F.: Les manifestations encephalitiques au cours de la grippe A , Neurologique 108:780, 1963. 10. Martelli, F., and Roggia, A.: L'encephalite grippale: Les complications neurologiques des grandes et des petites manifestations de la grippe , Rev Neurol 108:822, 1963. 11. Boudin, G., et al: Grippe et manifestations encéphalitiques , Rev Neurol 108:836, 1963. 12. Gianniotti, G.: Atteintes neurologiques au cours des récentes épidemies grippales , Rev Neurol 108:833, 1963. 13. Angelides, S.A., and Angelides, A.A.: Encephalitis During the Asian Influenza Pandemic of 1957 , Arch Inst Pasteur Hellen 8:83, 1962. 14. Pierri, O.D., et al: Encephalitis Associated With Influenzal Infection: Apropos of a Case , Rev Assoc Med Argent 77:308, 1963. 15. Stuart-Harris, C.H.: A Neurotropic Strain of Human Influenza Virus , Lancet 1:497, 1939.Crossref 16. Sabin, A.B.: "Pathologic and Virologic Studies on Three Cases of So-Called Postinfluenzal Encephalitis," in Encephalitides—Proceedings of a Symposium on the Neuropathology, Electroencephalography, and Biochemistries of Encephalitides, Antwerp, 1959 , Amsterdam: Elsevier Publishing Co., 1961. 17. Wintrobe, M.M.: Clinical Hematology , ed 5, Philadelphia: Lea and Febiger, 1961. 18. Ackroyd, J.F.: Allergic Purpura, Including Purpura Due to Foods, Drugs and Infections , Amer J Med 14:605, 1953.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Encephalitis and Purpura With Influenza Infection: A Case Report

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References (21)

Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1966.02090060112014
Publisher site
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Abstract

Abstract THE PROTEAN manifestations of influenza virus infections are well known. Encephalitis and purpura are rare complications of this infection, and our case is presented to document the occurrence of both these unusual findings in a child who was infected with the Asian influenza virus. Report of Case A 12-month-old boy was admitted to the San Francisco General Hospital on April 12, 1963. He had been in good health until three days prior to admission, at which time he developed rhinorrhea, sore throat, and a low-grade fever. On the day before admission his family physician noted congestion of the pharynx and tympanic membranes, and prescribed promethazine (Phenergan) and tetracycline. Several hours before admission the child had "bizarre movements" and could not sit up. Past medical history was noncontributory except for a primary smallpox vaccination 25 days prior to admission (March 18, 1963).On admission this child was irritable, moderately disoriented, with References 1. Bell, W.E.; McKee, A.P.; and Utterback, R.A.: Asian Influenza Virus as the Cause of Acute Encephalitis , Neurology 8:500, 1958.Crossref 2. Mellman, W.J.: Influenza Encephalitis , J Pediat 53: 292, 1958,Crossref 3. Flewett, T.H., and Hoult, J.G.: Influenzal Encephalopathy and Postinfluenzal Encephalitis , Lancet 2:11, 1958.Crossref 4. Dubowitz, V.: Influenzal Encephalitis , Lancet 1:140, 1958.Crossref 5. McConkey, B., and Daws, R.A.: Neurological Disorders Associated With Asian Influenza , Lancet 2:15, 1958.Crossref 6. Dunbar, J.M., et al: Encephalitis and Influenza , Brit Med J 1:913, 1958.Crossref 7. Anderson, W.W., and Jaros, R.M.: Neurologic Complications of Asian Influenza , Neurology 8:562, 1958. 8. Horner, F.A.: Neurologic Disorders After Asian Influenza , New Eng J Med 258:983, 1958.Crossref 9. Jellinger, K., and Seitelberger, F.: Les manifestations encephalitiques au cours de la grippe A , Neurologique 108:780, 1963. 10. Martelli, F., and Roggia, A.: L'encephalite grippale: Les complications neurologiques des grandes et des petites manifestations de la grippe , Rev Neurol 108:822, 1963. 11. Boudin, G., et al: Grippe et manifestations encéphalitiques , Rev Neurol 108:836, 1963. 12. Gianniotti, G.: Atteintes neurologiques au cours des récentes épidemies grippales , Rev Neurol 108:833, 1963. 13. Angelides, S.A., and Angelides, A.A.: Encephalitis During the Asian Influenza Pandemic of 1957 , Arch Inst Pasteur Hellen 8:83, 1962. 14. Pierri, O.D., et al: Encephalitis Associated With Influenzal Infection: Apropos of a Case , Rev Assoc Med Argent 77:308, 1963. 15. Stuart-Harris, C.H.: A Neurotropic Strain of Human Influenza Virus , Lancet 1:497, 1939.Crossref 16. Sabin, A.B.: "Pathologic and Virologic Studies on Three Cases of So-Called Postinfluenzal Encephalitis," in Encephalitides—Proceedings of a Symposium on the Neuropathology, Electroencephalography, and Biochemistries of Encephalitides, Antwerp, 1959 , Amsterdam: Elsevier Publishing Co., 1961. 17. Wintrobe, M.M.: Clinical Hematology , ed 5, Philadelphia: Lea and Febiger, 1961. 18. Ackroyd, J.F.: Allergic Purpura, Including Purpura Due to Foods, Drugs and Infections , Amer J Med 14:605, 1953.Crossref

Journal

American Journal of Diseases of Children – American Medical Association

Published: Mar 1, 1966

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