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POSSIBLE ROLE OF PLEUROPNEUMONIA-LIKE ORGANISMS IN ETIOLOGY OF DISEASE IN CHILDHOOD

POSSIBLE ROLE OF PLEUROPNEUMONIA-LIKE ORGANISMS IN ETIOLOGY OF DISEASE IN CHILDHOOD PLEUROPNEUMONIA-LIKE organisms, although known to produce disease in animals, are of questionable pathogenicity in human beings. They have been isolated repeatedly from the genitourinary tract, apparently as part of the normal flora of females, but possibly associated with nonspecific urethritis and Reiter's syndrome (nongonorrheal combination of arthritis, conjunctivitis and urethritis) in the male. The finding of similar pleuropneumonia-like organisms in blood cultures of two children with nonthrombocytopenic purpura and in one child with brain abscess and meningitis leads to the consideration of possible pathogenicity of such organisms in unsuspected situations in childhood. Pleuropneumonia-like organisms are a group of extremely pleomorphic, filtrable, poorly staining bodies that can be grown on enriched artificial mediums. Cultures consist of small granules and fine filaments. The small granules enlarge to form soft, spherical masses of varied size which finally rupture and free numerous daughter granules. The method of reproduction is in contrast to the usual http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

POSSIBLE ROLE OF PLEUROPNEUMONIA-LIKE ORGANISMS IN ETIOLOGY OF DISEASE IN CHILDHOOD

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References (25)

Publisher
American Medical Association
Copyright
Copyright © 1951 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1951.02040030202002
Publisher site
See Article on Publisher Site

Abstract

PLEUROPNEUMONIA-LIKE organisms, although known to produce disease in animals, are of questionable pathogenicity in human beings. They have been isolated repeatedly from the genitourinary tract, apparently as part of the normal flora of females, but possibly associated with nonspecific urethritis and Reiter's syndrome (nongonorrheal combination of arthritis, conjunctivitis and urethritis) in the male. The finding of similar pleuropneumonia-like organisms in blood cultures of two children with nonthrombocytopenic purpura and in one child with brain abscess and meningitis leads to the consideration of possible pathogenicity of such organisms in unsuspected situations in childhood. Pleuropneumonia-like organisms are a group of extremely pleomorphic, filtrable, poorly staining bodies that can be grown on enriched artificial mediums. Cultures consist of small granules and fine filaments. The small granules enlarge to form soft, spherical masses of varied size which finally rupture and free numerous daughter granules. The method of reproduction is in contrast to the usual

Journal

American journal of diseases of children – American Medical Association

Published: Feb 1, 1951

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