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SEVERE ERYTHROBLASTOSIS FETALIS AND ICTERUS PRECOX

SEVERE ERYTHROBLASTOSIS FETALIS AND ICTERUS PRECOX SINCE the literature is replete with evidence attesting to the etiologic role of the Rh factor in the pathogenesis of erythroblastosis fetalis in 90 per cent of the cases, it seems needless in this paper to dilate further on this subject. It is not generally recognized, however, that the A and B factors may also cause erythroblastosis fetalis,1 cases of which Halbrecht2 designated as icterus precox. In the case that will be reported here sensitization to the B factor was responsible for icterus precox three times in the same family. Moreover, the woman in question also had 2 full term babies with icterus gravis, both of whom died within three days, in spite of transfusions. REPORT OF CASES E. B., a quintipara, was referred to me because she had lost the second and fourth babies with icterus gravis, while the first, third and fifth babies survived. She was http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

SEVERE ERYTHROBLASTOSIS FETALIS AND ICTERUS PRECOX

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References (3)

Publisher
American Medical Association
Copyright
Copyright © 1949 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1949.02030040361006
Publisher site
See Article on Publisher Site

Abstract

SINCE the literature is replete with evidence attesting to the etiologic role of the Rh factor in the pathogenesis of erythroblastosis fetalis in 90 per cent of the cases, it seems needless in this paper to dilate further on this subject. It is not generally recognized, however, that the A and B factors may also cause erythroblastosis fetalis,1 cases of which Halbrecht2 designated as icterus precox. In the case that will be reported here sensitization to the B factor was responsible for icterus precox three times in the same family. Moreover, the woman in question also had 2 full term babies with icterus gravis, both of whom died within three days, in spite of transfusions. REPORT OF CASES E. B., a quintipara, was referred to me because she had lost the second and fourth babies with icterus gravis, while the first, third and fifth babies survived. She was

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Mar 1, 1949

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