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EFFECT OF TONSILLECTOMY AND OF ADENOIDECTOMY ON IMMUNITY TO DIPHTHERIA

EFFECT OF TONSILLECTOMY AND OF ADENOIDECTOMY ON IMMUNITY TO DIPHTHERIA In November, 1929, and again in May, 1931, Schick and one of us (Dr. Topper)1 reported the results of studies of the effect of tonsillectomy on immunity to diphtheria. Of 151 children who had shown a positive reaction to the Schick test before tonsillectomy, 123 (81.5 per cent) showed a negative reaction six months after tonsillectomy, while 28 (18.5 per cent) still gave a positive reaction. As the number of children whose reaction would normally become negative during this period is about from 10 to 15 per cent, it was concluded that tonsillectomy had in some way favored the development of a humoral immunity against diphtheria as measured by the Schick reaction. Since the publication of these reports, we have continued the study. In this paper, we report the results in 81 children who gave positive reactions before tonsillectomy and who returned for retesting six months later. All of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

EFFECT OF TONSILLECTOMY AND OF ADENOIDECTOMY ON IMMUNITY TO DIPHTHERIA

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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1933 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1933.01950170047002
Publisher site
See Article on Publisher Site

Abstract

In November, 1929, and again in May, 1931, Schick and one of us (Dr. Topper)1 reported the results of studies of the effect of tonsillectomy on immunity to diphtheria. Of 151 children who had shown a positive reaction to the Schick test before tonsillectomy, 123 (81.5 per cent) showed a negative reaction six months after tonsillectomy, while 28 (18.5 per cent) still gave a positive reaction. As the number of children whose reaction would normally become negative during this period is about from 10 to 15 per cent, it was concluded that tonsillectomy had in some way favored the development of a humoral immunity against diphtheria as measured by the Schick reaction. Since the publication of these reports, we have continued the study. In this paper, we report the results in 81 children who gave positive reactions before tonsillectomy and who returned for retesting six months later. All of

Journal

American journal of diseases of children – American Medical Association

Published: Apr 1, 1933

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