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CONGENITAL DEFECT OF THE SKIN OF THE NEW-BORN

CONGENITAL DEFECT OF THE SKIN OF THE NEW-BORN Congenital defect of the skin constitutes one of the rare and interesting anomalies peculiar to the new-born infant. Recently, a striking example of the condition came under our observation, and in view of the vast extent of the skin defect present in this infant, together with the rarity of its occurrence, a report of the case seems desirable. From the cases recorded in the literature, it is apparent that the lesions most frequently involve the scalp. They do occur, however, on the trunk and extremities, and in these locations the skin defects are often bilateral and also may be fairly symmetrical in their extent on the two sides of the body. The defects are present in early fetal life; thus they undoubtedly originate in utero. The margins of the involved areas are sharply defined and slightly elevated. Microscopic examination shows a failure in development, not only of the epidermis, but http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

CONGENITAL DEFECT OF THE SKIN OF THE NEW-BORN

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References (1)

Publisher
American Medical Association
Copyright
Copyright © 1924 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1924.01920070067007
Publisher site
See Article on Publisher Site

Abstract

Congenital defect of the skin constitutes one of the rare and interesting anomalies peculiar to the new-born infant. Recently, a striking example of the condition came under our observation, and in view of the vast extent of the skin defect present in this infant, together with the rarity of its occurrence, a report of the case seems desirable. From the cases recorded in the literature, it is apparent that the lesions most frequently involve the scalp. They do occur, however, on the trunk and extremities, and in these locations the skin defects are often bilateral and also may be fairly symmetrical in their extent on the two sides of the body. The defects are present in early fetal life; thus they undoubtedly originate in utero. The margins of the involved areas are sharply defined and slightly elevated. Microscopic examination shows a failure in development, not only of the epidermis, but

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Jan 1, 1924

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