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H. Akintürk, I. Michel-Behnke, K. Valeske, Matthias Mueller, J. Thul, J. Bauer, K. Hagel, D. Schranz (2007)
Hybrid Transcatheter–Surgical PalliationPediatric Cardiology, 28
Jeffrey Kern, Veronica Hinton, Nancy Nereo, C. Hayes, W. Gersony (1998)
Early Developmental Outcome After the Norwood Procedure for Hypoplastic Left Heart SyndromePediatrics, 102
A. Shillingford, R. Ittenbach, Bradley Marino, J. Rychik, Robert Clancy, T. Spray, J. Gaynor, G. Wernovsky (2007)
Aortic morphometry and microcephaly in hypoplastic left heart syndromeCardiology in the Young, 17
W. Mahle, T. Spray, J. Gaynor, B. Clark (2001)
Unexpected death after reconstructive surgery for hypoplastic left heart syndrome.The Annals of thoracic surgery, 71 1
M Galantowicz, JP Cheatham (2005)
Lessons learned from the development of a new hybrid strategy for the management of hypoplastic left heart syndrome [corrected and republished from: Pediatr Cardiol. 2005;26(2):190-199]., 26
H Akintürk, I Michel-Behnke, K Valeske (2007)
Hybrid transcatheter-surgical palliation: basis for univentricular or biventricular repair, the Giessen experience., 28
J. Berry, C. Cowley, C. Hoff, R. Srivastava (2006)
In-Hospital Mortality for Children With Hypoplastic Left Heart Syndrome After Stage I Surgical Palliation: Teaching Versus Nonteaching HospitalsPediatrics, 117
J. Tweddell, G. Hoffman, K. Mussatto, R. Fedderly, S. Berger, R. Jaquiss, N. Ghanayem, S. Frisbee, S. Litwin (2002)
Improved Survival of Patients Undergoing Palliation of Hypoplastic Left Heart Syndrome: Lessons Learned From 115 Consecutive PatientsCirculation: Journal of the American Heart Association, 106
P. Hagemo, A. Skarbø, M. Rasmussen, P. Fredriksen, Stein Schage (2006)
An extensive long term follow-up of a cohort of patients with hypoplasia of the left heartCardiology in the Young, 17
W. Mahle, Robert Clancy, E. Moss, M. Gerdes, D. Jobes, G. Wernovsky (2000)
Neurodevelopmental outcome and lifestyle assessment in school-aged and adolescent children with hypoplastic left heart syndrome.Pediatrics, 105 5
M. Baum, M. Freier, Kim Freeman, T. Babikian, S. Ashwal, R. Chinnock, L. Bailey (2004)
Neuropsychological outcome of infant heart transplant recipients.The Journal of pediatrics, 145 3
J. Gaynor, N. Bridges, Mitchell Cohen, W. Mahle, W. DeCampli, J. Steven, S. Nicolson, T. Spray (2002)
Predictors of outcome after the Fontan operation: is hypoplastic left heart syndrome still a risk factor?The Journal of thoracic and cardiovascular surgery, 123 2
S. Tabbutt, A. Nord, G. Jarvik, J. Bernbaum, G. Wernovsky, M. Gerdes, E. Zackai, Robert Clancy, S. Nicolson, T. Spray, J. Gaynor (2008)
Neurodevelopmental Outcomes After Staged Palliation for Hypoplastic Left Heart SyndromePediatrics, 121
E. Bacha, S. Daves, J. Hardin, R. Abdulla, Jennifer Anderson, M. Kahana, P. Koenig, B. Mora, M. Guleçyuz, J. Starr, E. Alboliras, S. Sandhu, Z. Hijazi (2006)
Single-ventricle palliation for high-risk neonates: the emergence of an alternative hybrid stage I strategy.The Journal of thoracic and cardiovascular surgery, 131 1
J. Kaltman, H. Di, Z. Tian, J. Rychik (2005)
Impact of congenital heart disease on cerebrovascular blood flow dynamics in the fetusUltrasound in Obstetrics and Gynecology, 25
L. Kaiser, I. Kron, T. Spray (1998)
Mastery of Cardiothoracic Surgery
C. Caldarone, L. Benson, H. Holtby, Jia Li, A. Redington, G. Arsdell (2007)
Initial experience with hybrid palliation for neonates with single-ventricle physiology.The Annals of thoracic surgery, 84 4
DG Nichols, DE Cameron
Critical Heart Disease in Infants and Children.
G. Wernovsky (2006)
Current insights regarding neurological and developmental abnormalities in children and young adults with complex congenital cardiac diseaseCardiology in the Young, 16
G. Wernovsky, N. Ghanayem, R. Ohye, E. Bacha, J. Jacobs, J. Gaynor, S. Tabbutt (2007)
Hypoplastic left heart syndrome: consensus and controversies in 2007Cardiology in the Young, 17
C Corrow, S Lapuk, K Mazzarella (2001)
Hypoplastic left heart syndrome., 65
W. Mahle, F. Tavani, R. Zimmerman, S. Nicolson, Kristin Galli, J. Gaynor, R. Clancy, L. Montenegro, T. Spray, R. Chiavacci, G. Wernovsky, C. Kurth (2002)
An MRI Study of Neurological Injury Before and After Congenital Heart SurgeryCirculation: Journal of the American Heart Association, 106
R. Freedom (2000)
Neurodevelopmental outcome after the fontan procedure in children with the hypoplastic left heart syndrome and other forms of single ventricle pathology: challenges unresolved.The Journal of pediatrics, 137 5
Kristin Galli, R. Zimmerman, G. Jarvik, G. Wernovsky, Marijn Kuypers, Robert Clancy, L. Montenegro, W. Mahle, M. Newman, A. Saunders, S. Nicolson, T. Spray, J. Gaynor (2004)
Periventricular leukomalacia is common after neonatal cardiac surgery.The Journal of thoracic and cardiovascular surgery, 127 3
C. Brosig, K. Mussatto, Evelyn Kuhn, J. Tweddell (2007)
Psychosocial Outcomes for Preschool Children and Families After Surgery for Complex Congenital Heart DiseasePediatric Cardiology, 28
G. Wernovsky, K. Stiles, K. Gauvreau, T. Gentles, A. Duplessis, D. Bellinger, A. Walsh, J. Burnett, R. Jonas, J. Mayer, J. Newburger (2000)
Cognitive development after the Fontan operation.Circulation, 102 8
G. Wernovsky, M. Chrisant (2004)
Long-term follow-up after staged reconstruction or transplantation for patients with functionally univentricular heartCardiology in the Young, 14
M. Mellander, L. Berntsson, B. Nilsson (2007)
Quality of life in children with hypoplastic left heart syndromeActa Pædiatrica, 96
S. Tabbutt, T. Dominguez, C. Ravishankar, B. Marino, P. Gruber, G. Wernovsky, J. Gaynor, S. Nicolson, T. Spray (2005)
Outcomes after the stage I reconstruction comparing the right ventricular to pulmonary artery conduit with the modified Blalock Taussig shunt.The Annals of thoracic surgery, 80 5
R. Behrman, R. Kliegman, H. Jenson (1965)
Nelson Textbook of PediatricsArchives of Disease in Childhood, 40
W. Mahle, T. Spray, G. Wernovsky, J. Gaynor, B. Clark (2000)
Survival After Reconstructive Surgery for Hypoplastic Left Heart Syndrome: A 15-Year Experience From a Single InstitutionCirculation: Journal of the American Heart Association, 102
T. Glauser, L. Rorke, P. Weinberg, Robert Clancy (1990)
Acquired neuropathologic lesions associated with the hypoplastic left heart syndrome.Pediatrics, 85 6
T. Kouchoukos (2003)
Kirklin/Barratt-Boyes Cardiac Surgery
M. Galantowicz, M. Galantowicz, J. Cheatham, J. Cheatham (2005)
Lessons Learned from the Development of a New Hybrid Strategy for the Management of Hypoplastic Left Heart SyndromePediatric Cardiology, 26
T. Gentles, K. Gauvreau, J. Mayer, S. Fishberger, Janice Burnetta, S. Colan, J. Newburger, G. Wernovsky (1997)
Functional outcome after the Fontan operation: factors influencing late morbidity.The Journal of thoracic and cardiovascular surgery, 114 3
S. Manzar, A. Nair, M. Pai, S. Al-Khusaiby (2005)
Head size at birth in neonates with transposition of great arteries and hypoplastic left heart syndrome.Saudi medical journal, 26 3
W. Thies, T. Breymann, D. Boethig, U. Blanz, H. Meyer, R. Koerfer (2003)
Results of staged reconstruction for hypoplasia of the left heart: an experience of 12 years from one institutionCardiology in the Young, 13
KK Galli, RA Zimmerman, GP Jarvik (2004)
Periventricular leukomalacia is common after neonatal cardiac surgery [erratum published in J Thorac Cardiovasc Surg. 2004;128(3):498. Galli, Kristen K (corrected to Galli, Kristin K)]., 127
Anne Sarajuuri, Eero Jokinen, R. Puosi, M. Eronen, L. Mildh, I. Mattila, L. Valanne, T. Lönnqvist (2007)
Neurodevelopmental and neuroradiologic outcomes in patients with univentricular heart aged 5 to 7 years: related risk factor analysis.The Journal of thoracic and cardiovascular surgery, 133 6
A. Moss, H. Allen (2016)
Moss and Adams' heart disease in infants, children, and adolescents : including the fetus and young adult
C. Pizarro, E. Malec, K. Maher, K. Januszewska, S. Gidding, K. Murdison, J. Baffa, W. Norwood (2003)
Right Ventricle to Pulmonary Artery Conduit Improves Outcome After Stage I Norwood for Hypoplastic Left Heart SyndromeCirculation: Journal of the American Heart Association, 108
P. Jenkins, M. Flanagan, J. Sargent, C. Canter, R. Chinnock, K. Jenkins, R. Vincent, G. O'connor, A. Tosteson (2001)
A comparison of treatment strategies for hypoplastic left heart syndrome using decision analysis.Journal of the American College of Cardiology, 38 4
H. Taeusch, R. Ballard (1998)
Avery's Diseases of the Newborn
T. Glauser, L. Rorke, P. Weinberg, Robert Clancy (1990)
Congenital brain anomalies associated with the hypoplastic left heart syndrome.Pediatrics, 85 6
W. Mahle, Karen Visconti, M. Freier, S. Kanne, William Hamilton, A. Sharkey, R. Chinnock, K. Jenkins, Peter Isquith, T. Burns, P. Jenkins (2006)
Relationship of Surgical Approach to Neurodevelopmental Outcomes in Hypoplastic Left Heart SyndromePediatrics, 117
C. Goldberg, E. Schwartz, J. Brunberg, R. Mosca, E. Bove, M. Schork, Sharon Stetz, J. Cheatham, T. Kulik (2000)
Neurodevelopmental outcome of patients after the fontan operation: A comparison between children with hypoplastic left heart syndrome and other functional single ventricle lesions.The Journal of pediatrics, 137 5
M. Mitchell, R. Ittenbach, J. Gaynor, G. Wernovsky, S. Nicolson, T. Spray (2006)
Intermediate outcomes after the Fontan procedure in the current era.The Journal of thoracic and cardiovascular surgery, 131 1
R. Clancy (2003)
The Neurology of Hypoplastic Left Heart Syndrome
S. Gandhi, C. Canter, A. Kulikowska, C. Huddleston (2007)
Infant heart transplantation ten years later--where are they now?The Annals of thoracic surgery, 83 1
COMMENTARY The Paradigm Shift Toward Surgical Intervention for Neonates With Hypoplastic Left Heart Syndrome HOULD NONINTERVEN- progress that has been made in HLHS with ongoing surgical modification; tion (or what some phy- inthepast2decadeshasbeenparticu- and,importantly,childrenwithHLHS sicianscall comfort care) larlyrewardingandformsthebasisof are at no greater risk of mortality or beofferedasanoptionto my opinions. short-term morbidity following the S parentsofneonateswith Fontanprocedurethanotherchildren hypoplastic left heart syndrome with complex CHD with a function- GOOD COUNSELING 17,18 (HLHS)? While this may have been a ally univentricular heart. Alterna- BEGINS WITH GOOD DATA reasonablechoice2decadesago,Iwill tivestostagedreconstructioninclude 19-21 arguethat—for2primaryreasonshav- primarycardiactransplantation or What is our current best understand- ing to do with improvements in out- ahybridstrategycombininginterven- ing of HLHS and the associated comes over time and by comparing tionalcatheterizationtechniqueswith short- and long-term outcomes? Hy- HLHS with other life-threatening pe- surgery,ultimatelyfollowedbyaneven poplastic left heart syndrome is an diatric conditions—nonintervention newer modification of the Fontan uncommon condition, affecting ap- should no longer be offered. 22-25 principle. proximately1 in 5000 newborns an- Whichever intervention is per- nually in the United States, which See also page 844 formed, there is an on-going hazard translates into nearly 1000 neo- of premature mortality, repeated hos- nates per year born with HLHS and pitalizations, and reduced ability to
JAMA Pediatrics – American Medical Association
Published: Sep 1, 2008
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