Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Tumor Thickness in Early Tongue Cancer

Tumor Thickness in Early Tongue Cancer Abstract Objective: To review the relationship between tumor thickness and the subsequent development of cervical nodal metastases in 26 patients with stage I and II carcinomas of the oral tongue. Methods: The histologic features of 26 consecutive patients treated for squamous carcinoma of the oral tongue were reviewed "blindly" by a pathologist, and the variables were correlated with clinical outcome. Results: No association between tumor thickness and nodal metastases was found. Perineural infiltration was the only factor to approach statistical significance. There was also no statistically significant correlation between tumor thickness and patient survival. Conclusions: The histologic factors considered herein probably should be controlled for when comparing results of treatment of cancer of the oral tongue.(Arch Otolaryngol Head Neck Surg. 1994;120:717-720) References 1. Spiro RH, Huvos AG, Wong GY, Spiro JD, Gnecco CA, Strong EW. Predictive value of tumor thickness in squamous carcinoma confined to the tongue and floor of the mouth . Am J Surg. 1986;152:345-350.Crossref 2. Fakih AR, Rao RS, Borges AM, Patel AR. Elective versus therapeutic neck dissection in early carcinoma of the tongue . Am J Surg. 1989;158:309-313.Crossref 3. Rasgon BM, Cruz RM, Hilsinger RL, Sawicki JE. Relation of lymph-node metastasis to histopathologic appearance in oral cavity and oropharyngeal carcinoma: a case series and literature review . Laryngoscope . 1989;99:1103-1109.Crossref 4. O'Brien CJ, Lahr CJ, Soong S-J, et al. Surgical treatment of early-stage carcinoma of the oral tongue: would adjuvant treatment be beneficial? Head Neck . 1986;8:401-408.Crossref 5. Silver CE, Moisa II. Elective treatment of the neck in cancer of the oral tongue . Semin Surg Oncol. 1991;7:14-19.Crossref 6. Bradfield JS, Scruggs RP. Carcinoma of the mobile tongue: incidence of cervical metastases in early lesions related to method of primary treatment . Laryngoscope . 1983;93:1332-1336. 7. Shear M, Hawkins DM, Farr HW. The prediction of lymph node metastases from oral squamous carcinoma . Cancer . 1976;37:1901-1907.Crossref 8. Johnson JT, Leipzig B, Cummings CW. Management of T1 carcinoma of the anterior aspect of the tongue . Arch Otolaryngol. 1980;106:249-251.Crossref 9. Spiro RH, Strong EW. Epidermoid carcinoma of the oral cavity and oropharynx: elective vs therapeutic radical neck dissection as treatment . Arch Surg. 1973;107:382-384. 10. Whitehouse JO, Droulias CA. Surgical treatment of squamous carcinoma of the oral tongue . Arch Otolaryngol. 1977;103:212-215.Crossref 11. Spaulding CA, Korb LJ, Constable WC, Canterell RW, Levine PA. The influence of extent of neck treatment upon control of cervical lymphadenopathy in cancers of the oral tongue . Int J Radiat Oncol Biol Phys. 1991;3:577-581.Crossref 12. Mohit-Tabatabai MA, Sobel HJ, Rush BF, Mashberg A. Relation of thickness of floor of mouth stage I and II cancers to regional metastasis . Am J Surg. 1986; 152:351-353.Crossref 13. Urist MM, O'Brien CJ, Soong SJ, Visscher DW, Maddox WA. Squamous carcinoma of the buccal mucosa: analysis of prognostic factors . Am J Surg. 1987; 154:411-414.Crossref 14. Frierson HF, Cooper PH. Prognostic factors in squamous cell carcinoma of the lower lip . Hum Pathol. 1986;17:346-354.Crossref 15. Moore C, Kuhns JG, Greenberg RA. Thickness as a prognostic aid in upper aerodigestive tract cancer . Arch Surg. 1986;121:1410-1414.Crossref 16. Borges AM, Shrikhande SS, Ganesh B. Surgical pathology of squamous carcinoma of the oral cavity: its impact on management . Semin Surg Oncol. 1989; 5:310-317.Crossref 17. Close LG, Brown PM, Vuitch MF, Reisch J, Schaefer SD. Microvascular invasion and survival in cancer of the oral cavity and oropharynx . Arch Otolaryngol Head Neck Surg. 1989;115:1304-1309.Crossref 18. Maddox WA, Urist MM. Histopathological prognostic factors of certain primary oral cavity cancers . Oncology . 1990;4:39-42. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology - Head & Neck Surgery American Medical Association

Tumor Thickness in Early Tongue Cancer

Download PDF
4 pages

Loading next page...
 
/lp/american-medical-association/tumor-thickness-in-early-tongue-cancer-t4KTK6cSot

References (19)

Publisher
American Medical Association
Copyright
Copyright © 1994 American Medical Association. All Rights Reserved.
ISSN
0886-4470
eISSN
1538-361X
DOI
10.1001/archotol.1994.01880310023005
Publisher site
See Article on Publisher Site

Abstract

Abstract Objective: To review the relationship between tumor thickness and the subsequent development of cervical nodal metastases in 26 patients with stage I and II carcinomas of the oral tongue. Methods: The histologic features of 26 consecutive patients treated for squamous carcinoma of the oral tongue were reviewed "blindly" by a pathologist, and the variables were correlated with clinical outcome. Results: No association between tumor thickness and nodal metastases was found. Perineural infiltration was the only factor to approach statistical significance. There was also no statistically significant correlation between tumor thickness and patient survival. Conclusions: The histologic factors considered herein probably should be controlled for when comparing results of treatment of cancer of the oral tongue.(Arch Otolaryngol Head Neck Surg. 1994;120:717-720) References 1. Spiro RH, Huvos AG, Wong GY, Spiro JD, Gnecco CA, Strong EW. Predictive value of tumor thickness in squamous carcinoma confined to the tongue and floor of the mouth . Am J Surg. 1986;152:345-350.Crossref 2. Fakih AR, Rao RS, Borges AM, Patel AR. Elective versus therapeutic neck dissection in early carcinoma of the tongue . Am J Surg. 1989;158:309-313.Crossref 3. Rasgon BM, Cruz RM, Hilsinger RL, Sawicki JE. Relation of lymph-node metastasis to histopathologic appearance in oral cavity and oropharyngeal carcinoma: a case series and literature review . Laryngoscope . 1989;99:1103-1109.Crossref 4. O'Brien CJ, Lahr CJ, Soong S-J, et al. Surgical treatment of early-stage carcinoma of the oral tongue: would adjuvant treatment be beneficial? Head Neck . 1986;8:401-408.Crossref 5. Silver CE, Moisa II. Elective treatment of the neck in cancer of the oral tongue . Semin Surg Oncol. 1991;7:14-19.Crossref 6. Bradfield JS, Scruggs RP. Carcinoma of the mobile tongue: incidence of cervical metastases in early lesions related to method of primary treatment . Laryngoscope . 1983;93:1332-1336. 7. Shear M, Hawkins DM, Farr HW. The prediction of lymph node metastases from oral squamous carcinoma . Cancer . 1976;37:1901-1907.Crossref 8. Johnson JT, Leipzig B, Cummings CW. Management of T1 carcinoma of the anterior aspect of the tongue . Arch Otolaryngol. 1980;106:249-251.Crossref 9. Spiro RH, Strong EW. Epidermoid carcinoma of the oral cavity and oropharynx: elective vs therapeutic radical neck dissection as treatment . Arch Surg. 1973;107:382-384. 10. Whitehouse JO, Droulias CA. Surgical treatment of squamous carcinoma of the oral tongue . Arch Otolaryngol. 1977;103:212-215.Crossref 11. Spaulding CA, Korb LJ, Constable WC, Canterell RW, Levine PA. The influence of extent of neck treatment upon control of cervical lymphadenopathy in cancers of the oral tongue . Int J Radiat Oncol Biol Phys. 1991;3:577-581.Crossref 12. Mohit-Tabatabai MA, Sobel HJ, Rush BF, Mashberg A. Relation of thickness of floor of mouth stage I and II cancers to regional metastasis . Am J Surg. 1986; 152:351-353.Crossref 13. Urist MM, O'Brien CJ, Soong SJ, Visscher DW, Maddox WA. Squamous carcinoma of the buccal mucosa: analysis of prognostic factors . Am J Surg. 1987; 154:411-414.Crossref 14. Frierson HF, Cooper PH. Prognostic factors in squamous cell carcinoma of the lower lip . Hum Pathol. 1986;17:346-354.Crossref 15. Moore C, Kuhns JG, Greenberg RA. Thickness as a prognostic aid in upper aerodigestive tract cancer . Arch Surg. 1986;121:1410-1414.Crossref 16. Borges AM, Shrikhande SS, Ganesh B. Surgical pathology of squamous carcinoma of the oral cavity: its impact on management . Semin Surg Oncol. 1989; 5:310-317.Crossref 17. Close LG, Brown PM, Vuitch MF, Reisch J, Schaefer SD. Microvascular invasion and survival in cancer of the oral cavity and oropharynx . Arch Otolaryngol Head Neck Surg. 1989;115:1304-1309.Crossref 18. Maddox WA, Urist MM. Histopathological prognostic factors of certain primary oral cavity cancers . Oncology . 1990;4:39-42.

Journal

Archives of Otolaryngology - Head & Neck Surgery – American Medical Association

Published: Jul 1, 1994

There are no references for this article.