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Sinonasal Undifferentiated Carcinoma

Sinonasal Undifferentiated Carcinoma This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Paul A. Levine, MD, and collaborators at the University of Virginia, Charlottesville, recently reported 11 cases of undifferentiated carcinoma of the nose and sinuses whose features were pathologically and clinically distinct from those of other malignancies at these sites. Their report, presented at the Southern Section Meeting of the Triological Society in Santa Fe, NM, emphasized the aggressive nature of this neoplasm, which they called sinonasal undifferentiated carcinoma. Six of the patients had orbital involvement, and seven had anterior cranial fossa involvement. Most patients' tumors were unresectable (seven of 11), and the patients received chemotherapy and radiotherapy. Eight (73% ) of 11 patients died with disease, and, of the three still living, only one is free of disease. The authors stated that presenting symptoms are not unlike those of other tumors that arise in these sites, and the differential diagnosis should include esthesioneuroblastoma, melanoma, rhabdomyosarcoma, neuroendocrine carcinoma, and lymphoepithelioma. Special histologic http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology - Head & Neck Surgery American Medical Association

Sinonasal Undifferentiated Carcinoma

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Paul A. Levine, MD, and collaborators at the University of Virginia, Charlottesville, recently reported 11 cases of undifferentiated carcinoma of the nose and sinuses whose features were pathologically and clinically distinct from those of other malignancies at these sites. Their report, presented at the Southern Section Meeting of the Triological...
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Publisher
American Medical Association
Copyright
Copyright © 1987 American Medical Association. All Rights Reserved.
ISSN
0886-4470
eISSN
1538-361X
DOI
10.1001/archotol.1987.01860040015001
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Paul A. Levine, MD, and collaborators at the University of Virginia, Charlottesville, recently reported 11 cases of undifferentiated carcinoma of the nose and sinuses whose features were pathologically and clinically distinct from those of other malignancies at these sites. Their report, presented at the Southern Section Meeting of the Triological Society in Santa Fe, NM, emphasized the aggressive nature of this neoplasm, which they called sinonasal undifferentiated carcinoma. Six of the patients had orbital involvement, and seven had anterior cranial fossa involvement. Most patients' tumors were unresectable (seven of 11), and the patients received chemotherapy and radiotherapy. Eight (73% ) of 11 patients died with disease, and, of the three still living, only one is free of disease. The authors stated that presenting symptoms are not unlike those of other tumors that arise in these sites, and the differential diagnosis should include esthesioneuroblastoma, melanoma, rhabdomyosarcoma, neuroendocrine carcinoma, and lymphoepithelioma. Special histologic

Journal

Archives of Otolaryngology - Head & Neck SurgeryAmerican Medical Association

Published: Apr 1, 1987

There are no references for this article.