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Kawasaki Disease in Adults: An Otolaryngologist's Perspective

Kawasaki Disease in Adults: An Otolaryngologist's Perspective Abstract • Kawasaki disease has been recognized for more than 15 years in children, but it is only recently that adult cases have been known to occur. One such case is reported herein. The cases of previously described adult patients are reviewed in depth, emphasizing the otolaryngologic findings. Diagnosis is based on clinical findings with prominent fever, oropharyngeal erythema, dermatitis, and cervical lymphadenopathy. The underlying lesion is a vasculitis and treatment is mainly supportive, although aspirin seems to have some value in the prevention of cardiac complications. (Arch Otolaryngol 1984;110:543-545) References 1. Kawasaki T: Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of fingers and toes . Arerugi 1967;16:178-222. 2. Gomberg R, Homm P: Mucocutaneous lymph node syndrome in an adult . West J Med 1981;135:406-408. 3. Milgrom H, Plamer E, Slovin S, et al: Kawasaki disease in a healthy young adult . Ann Intern Med 1980;92:467-470.Crossref 4. Hick JT, Korenyi-Both A, Utisinger PD, et al: Neuromuscular and immunochemical abnormalities in an adult man with Kawasaki disease . Ann Intern Med 1982;96:607-610.Crossref 5. Schlossberg D, Kandra J, Kreiser J: Possible Kawasaki disease in a 20-year-old woman . Arch Dermatol 1979;115:1435-1436.Crossref 6. Glanzer M, Galbraith W: Kawasaki disease in a 28-year-old man . JAMA 1980;244:1604-1606.Crossref 7. Everett E: Mucocutaneous lymph node syndrome (Kawasaki disease) in adults . JAMA 1979; 242:542-543.Crossref 8. Liebmann LI, Mikelic V, Joh M, et al: Hydrops of the gallbladder in an adult with Kawasaki disease . JAMA 1982;247:827-829.Crossref 9. Barbour AG, Krueger GC, Feorino PM, et al: Kawasaki-like disease in a young adult: Association with primary Epstein-Barr virus infection . JAMA 1979;24:397-398.Crossref 10. Lee T, Vaughn D: Adult Kawasaki disease . Arch Intern Med 1979;139:104-105.Crossref 11. Bell D, Brink E, Nitzkin J, et al: Kawasaki syndrome: Description of two outbreaks in the United States . N Engl J Med 1981;304:1568-1575.Crossref 12. Melish M: Kawasaki syndrome . Annu Rev Med 1982;33:569-585.Crossref 13. Trepo CG, Fukerman AJ, Brid RC, et al: The role of circulating hepatitic B antigen/ antibody immune complexes in the pathogenesis of vascular and hepatic manifestations in polyarteritis nodosa . J Clin Pathol 1974;27:863-868.Crossref 14. Melish ME, Hicks RV, Reddy V: Kawasaki syndrome: An update . Hosp Pract 1982;17:99-106. 15. Chung K, Brandt L, Fulton D, et al: Cardiac and coronary involvement in children from New England with mucocutaneous lymph node syndrome . Am J Cardiol 1982;50:136-142.Crossref 16. Suma K, Yasuo T, Shiroma K, et al: Early and late postoperative studies in coronary arterial lesions resulting from Kawasaki's disease in children . J Thorac Cardiovasc Surg 1982;84:224-229. 17. Kato H, Koike S, Yamamoto M, et al: Coronary aneurysms in infants and young chindren with acute febrile mucocutaneous lymph node syndrome . J Pediatr 1975;86:892-898.Crossref 18. Jacobs JC: Salicylate treatment of epidemic Kawasaki disease in New York City . Ther Drug Monit 1979;1:123-130.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

Kawasaki Disease in Adults: An Otolaryngologist's Perspective

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References (23)

Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1984.00800340055016
Publisher site
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Abstract

Abstract • Kawasaki disease has been recognized for more than 15 years in children, but it is only recently that adult cases have been known to occur. One such case is reported herein. The cases of previously described adult patients are reviewed in depth, emphasizing the otolaryngologic findings. Diagnosis is based on clinical findings with prominent fever, oropharyngeal erythema, dermatitis, and cervical lymphadenopathy. The underlying lesion is a vasculitis and treatment is mainly supportive, although aspirin seems to have some value in the prevention of cardiac complications. (Arch Otolaryngol 1984;110:543-545) References 1. Kawasaki T: Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of fingers and toes . Arerugi 1967;16:178-222. 2. Gomberg R, Homm P: Mucocutaneous lymph node syndrome in an adult . West J Med 1981;135:406-408. 3. Milgrom H, Plamer E, Slovin S, et al: Kawasaki disease in a healthy young adult . Ann Intern Med 1980;92:467-470.Crossref 4. Hick JT, Korenyi-Both A, Utisinger PD, et al: Neuromuscular and immunochemical abnormalities in an adult man with Kawasaki disease . Ann Intern Med 1982;96:607-610.Crossref 5. Schlossberg D, Kandra J, Kreiser J: Possible Kawasaki disease in a 20-year-old woman . Arch Dermatol 1979;115:1435-1436.Crossref 6. Glanzer M, Galbraith W: Kawasaki disease in a 28-year-old man . JAMA 1980;244:1604-1606.Crossref 7. Everett E: Mucocutaneous lymph node syndrome (Kawasaki disease) in adults . JAMA 1979; 242:542-543.Crossref 8. Liebmann LI, Mikelic V, Joh M, et al: Hydrops of the gallbladder in an adult with Kawasaki disease . JAMA 1982;247:827-829.Crossref 9. Barbour AG, Krueger GC, Feorino PM, et al: Kawasaki-like disease in a young adult: Association with primary Epstein-Barr virus infection . JAMA 1979;24:397-398.Crossref 10. Lee T, Vaughn D: Adult Kawasaki disease . Arch Intern Med 1979;139:104-105.Crossref 11. Bell D, Brink E, Nitzkin J, et al: Kawasaki syndrome: Description of two outbreaks in the United States . N Engl J Med 1981;304:1568-1575.Crossref 12. Melish M: Kawasaki syndrome . Annu Rev Med 1982;33:569-585.Crossref 13. Trepo CG, Fukerman AJ, Brid RC, et al: The role of circulating hepatitic B antigen/ antibody immune complexes in the pathogenesis of vascular and hepatic manifestations in polyarteritis nodosa . J Clin Pathol 1974;27:863-868.Crossref 14. Melish ME, Hicks RV, Reddy V: Kawasaki syndrome: An update . Hosp Pract 1982;17:99-106. 15. Chung K, Brandt L, Fulton D, et al: Cardiac and coronary involvement in children from New England with mucocutaneous lymph node syndrome . Am J Cardiol 1982;50:136-142.Crossref 16. Suma K, Yasuo T, Shiroma K, et al: Early and late postoperative studies in coronary arterial lesions resulting from Kawasaki's disease in children . J Thorac Cardiovasc Surg 1982;84:224-229. 17. Kato H, Koike S, Yamamoto M, et al: Coronary aneurysms in infants and young chindren with acute febrile mucocutaneous lymph node syndrome . J Pediatr 1975;86:892-898.Crossref 18. Jacobs JC: Salicylate treatment of epidemic Kawasaki disease in New York City . Ther Drug Monit 1979;1:123-130.Crossref

Journal

Archives of Otolaryngology – American Medical Association

Published: Aug 1, 1984

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