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Benign Lymphoepithelial Lesion of the Parotid Gland: Mikulicz's Disease

Benign Lymphoepithelial Lesion of the Parotid Gland: Mikulicz's Disease Abstract THIS tumor-like disease has been described under different names: lymphoepithelioma,1 adenolymphoma,2 and other terms such as chronic inflammation, lymphocytic tumor, adenoma-lymphomatosum, Mikulicz disease, and solid adenolymphoma. Whether this is an inflammatory or neoplastic disease is a problem which has yet to be solved. Godwin3 proposed the term "benign lymphoepithelial lesion" because some of the manifestations of this pathologic process would seem to be of a fundamentally inflammatory nature, whereas others would seem more appropriately neoplastic. This process may be present in scattered foci, it may diffusely involve the entire gland, be localized to a single, nonencapsulated focus, or, finally, be circumscribed and encapsulated.4 In some cases, more than one, or all, of these different forms may be present simultaneously, or may follow one another. Microscopically, these lesions are composed predominantly of lymphoid tissue, with smaller and larger epithelial islands scattered throughout. The lymphoid tissue is regular References 1. Fein, M.J.: Lymphoepithelioma of the Parotid Gland , Amer J Cancer 40:434-440 ( (March) ) 1940. 2. Heinz, J.: The Adenolymphomata , Aust New Zeal J Surg 21:47-51 ( (Aug) ) 1951.Crossref 3. Godwin, J.R.: Benign Lymphoepithelial Lesion of the Parotid Gland: Report of Eleven Cases , Cancer 5:1089-1103 ( (July) ) 1952.Crossref 4. Foote, F.W., and Frazell, E.L.: "Tumours of the Major Salivary Glands," in Atlas of Tumor Pathology , Armed Forces Institute of Pathology, 1954, pp 142-147. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

Benign Lymphoepithelial Lesion of the Parotid Gland: Mikulicz's Disease

Schindel, J.; Levie, B.
Archives of Otolaryngology , Volume 90 (4) – Oct 1, 1969
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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1969.00770030498017
Publisher site
See Article on Publisher Site

Abstract

Abstract THIS tumor-like disease has been described under different names: lymphoepithelioma,1 adenolymphoma,2 and other terms such as chronic inflammation, lymphocytic tumor, adenoma-lymphomatosum, Mikulicz disease, and solid adenolymphoma. Whether this is an inflammatory or neoplastic disease is a problem which has yet to be solved. Godwin3 proposed the term "benign lymphoepithelial lesion" because some of the manifestations of this pathologic process would seem to be of a fundamentally inflammatory nature, whereas others would seem more appropriately neoplastic. This process may be present in scattered foci, it may diffusely involve the entire gland, be localized to a single, nonencapsulated focus, or, finally, be circumscribed and encapsulated.4 In some cases, more than one, or all, of these different forms may be present simultaneously, or may follow one another. Microscopically, these lesions are composed predominantly of lymphoid tissue, with smaller and larger epithelial islands scattered throughout. The lymphoid tissue is regular References 1. Fein, M.J.: Lymphoepithelioma of the Parotid Gland , Amer J Cancer 40:434-440 ( (March) ) 1940. 2. Heinz, J.: The Adenolymphomata , Aust New Zeal J Surg 21:47-51 ( (Aug) ) 1951.Crossref 3. Godwin, J.R.: Benign Lymphoepithelial Lesion of the Parotid Gland: Report of Eleven Cases , Cancer 5:1089-1103 ( (July) ) 1952.Crossref 4. Foote, F.W., and Frazell, E.L.: "Tumours of the Major Salivary Glands," in Atlas of Tumor Pathology , Armed Forces Institute of Pathology, 1954, pp 142-147.

Journal

Archives of Otolaryngology – American Medical Association

Published: Oct 1, 1969

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