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Ménière's Disease

Ménière's Disease Abstract AS DESCRIBED BY Clemis and Shambaugh,1 Ménière's disease is a common, chronic, and benign disorder of the inner ear, due to increased pressure of endolymphatic fluid, resulting in attacks of vertigo, in loss of sensorineural hearing, in tinnitus, and in a sensation of fullness or pressure in the ear; any one or all symptoms may be present. Especially characteristic of this disease are natural spontaneous remissions and exacerbations which make therapeutic results difficult to assess. Shambaugh2 suggests that the saccus endolymphaticus may hold the key to an understanding of Ménière's disease. It appears that deficient resorption of endolymph by the endolymphatic sac may be the reason for the excess volume of endolymph. Shambaugh was first to report that brisk bleeding is normally observed from the wall of the endolymphatic sac is it is uncovered. In contrast, he has been impressed with rather marked ischemia of the sac wall References 1. Conn, H.F.: Current Therapy: Ménière's Disease, Method of Jack D. Clemis, MD, and George E. Shambaugh, Jr., MD , Philadelphia: W. B. Saunders Co., 1965. 2. Shambaugh, G.E.: Symposium on Vertigo , Arch Otolaryng 85:497-560 ( (May) ) 1967.Crossref 3. Shelden, C.H., and Horton, B.T.: Treatment of Ménière's Disease With Histamine Administered Intravenously , Proc Staff Meet Mayo Clin 15:17-21, 1940. 4. Shambaugh, G.E.: Ménière's Disease: Diagnosis and Treatment , Texas J Med 58:70-74, 1962. 5. Elia, J.C.: Double-Blind Evaluation of a New Treatment for Ménière's Syndrome , JAMA 196:187-189, 1966.Crossref 6. Boies, L.R.; Hilger, J.A.; and Priest, R.E.: Fundamentals of Otolaryngology , Philadelphia: W. B. Saunders Co., 1964. 7. Wells, R.E., Jr.: Rheology of Blood in the Microvasculature , New Eng J Med 270:832-839 ( (Apirl 16) ) 1964Crossref 8. 889-893 (April 23) 1964. 9. Hunt, W.H., and Fosbinder, R.J.: A Study of Some Beta-2, and 4, Pyridylalkylamines , J Pharmacol Exp Ther 75:299-307 ( (Aug) ) 1942. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

Ménière's Disease

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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1967 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1967.00760050612003
Publisher site
See Article on Publisher Site

Abstract

Abstract AS DESCRIBED BY Clemis and Shambaugh,1 Ménière's disease is a common, chronic, and benign disorder of the inner ear, due to increased pressure of endolymphatic fluid, resulting in attacks of vertigo, in loss of sensorineural hearing, in tinnitus, and in a sensation of fullness or pressure in the ear; any one or all symptoms may be present. Especially characteristic of this disease are natural spontaneous remissions and exacerbations which make therapeutic results difficult to assess. Shambaugh2 suggests that the saccus endolymphaticus may hold the key to an understanding of Ménière's disease. It appears that deficient resorption of endolymph by the endolymphatic sac may be the reason for the excess volume of endolymph. Shambaugh was first to report that brisk bleeding is normally observed from the wall of the endolymphatic sac is it is uncovered. In contrast, he has been impressed with rather marked ischemia of the sac wall References 1. Conn, H.F.: Current Therapy: Ménière's Disease, Method of Jack D. Clemis, MD, and George E. Shambaugh, Jr., MD , Philadelphia: W. B. Saunders Co., 1965. 2. Shambaugh, G.E.: Symposium on Vertigo , Arch Otolaryng 85:497-560 ( (May) ) 1967.Crossref 3. Shelden, C.H., and Horton, B.T.: Treatment of Ménière's Disease With Histamine Administered Intravenously , Proc Staff Meet Mayo Clin 15:17-21, 1940. 4. Shambaugh, G.E.: Ménière's Disease: Diagnosis and Treatment , Texas J Med 58:70-74, 1962. 5. Elia, J.C.: Double-Blind Evaluation of a New Treatment for Ménière's Syndrome , JAMA 196:187-189, 1966.Crossref 6. Boies, L.R.; Hilger, J.A.; and Priest, R.E.: Fundamentals of Otolaryngology , Philadelphia: W. B. Saunders Co., 1964. 7. Wells, R.E., Jr.: Rheology of Blood in the Microvasculature , New Eng J Med 270:832-839 ( (Apirl 16) ) 1964Crossref 8. 889-893 (April 23) 1964. 9. Hunt, W.H., and Fosbinder, R.J.: A Study of Some Beta-2, and 4, Pyridylalkylamines , J Pharmacol Exp Ther 75:299-307 ( (Aug) ) 1942.

Journal

Archives of Otolaryngology – American Medical Association

Published: Dec 1, 1967

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