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Bell's Palsy: A New Syndrome Associated with Treatment by Nicotinic Acid: A Guide to Adequate Medical Therapy

Bell's Palsy: A New Syndrome Associated with Treatment by Nicotinic Acid: A Guide to Adequate... Abstract Bell's palsy—facial nerve paralysis—has been defined as an ischemic palsy of the seventh cranial nerve. It is sympathetic paralysis, apparently due to a vasoconstriction of the arterioles of the peripheral perineural vascular channels of the seventh cranial nerve.1 There is usually a history of exposure to cold or draft on the affected side, although many patients will not recall such incidence of exposure. It has been implied that a hyperactivity or activation of the sympathetic nervous system neuropathways will cause a vasoconstriction of the arterioles, which in many parts of the face will show no direct evidence of tissue involvement such as paleness of the underlying skin. If the small and none too plentiful arterioles of the seventh nerve are involved, the vasoconstriction will start a chain of events wherein ischemia, capillary dilatation, transudation, edema of the nerve and nerve sheath will occur, then associated loss of function, that References 1. Martin, R. C.: Symposium on Facial Paralysis: Bell's Palsy , A. M. A. Arch. Otolaryng. 55:405-409 ( (April) ) 1952.Crossref 2. Duel, A. B.: Clinical Experiences in Surgical Treatment of Facial Palsy by Autoplastic Nerve Grafts: Ballance-Duel Method , Arch. Otolaryng. 16:767-788 ( (Dec.) ) 1932.Crossref 3. Mettler, F. A.: Neuroanatomy , Ed. 2, St. Louis, The C. V. Mosby Company, 1948, pp. 240-241. 4. Skolnik, E. M.: Electrodiagnosis of Lesions of Facial Nerve , J. Internat. Coll. Surgeons 23:371-380 ( (March) ) 1955. 5. Sullivan, J. A., and Smith, J. B.: Otological Concept of Bell's Palsy and Its Treatment , Ann. Otol. Rhin. & Laryng. 59:1148-1170 ( (Dec.) ) 1950. 6. Skinner, D. A.: Histamine in Bell's Palsy , Ophth. Tr. Am. Acad. 56:283-286 ( (March) -April) 1952. 7. Good, R. P.: Histamine in Bell's Palsy , Indiana Acad. Ophth. , pp. 1-5, 1954. 8. Hilger, J. A.: The Nature of Bell's Palsy , Laryngoscope 59:228-235 ( (March) ) 1949. 9. Hall, A.: Pathology of Bell's Palsy , A. M. A. Arch. Otolaryng. 54:475-477 ( (Nov.) ) 1951. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Otolaryngology American Medical Association

Bell's Palsy: A New Syndrome Associated with Treatment by Nicotinic Acid: A Guide to Adequate Medical Therapy

A.M.A. Archives of Otolaryngology , Volume 68 (1) – Jul 1, 1958

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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1958 American Medical Association. All Rights Reserved.
ISSN
0096-6894
DOI
10.1001/archotol.1958.00730020032004
Publisher site
See Article on Publisher Site

Abstract

Abstract Bell's palsy—facial nerve paralysis—has been defined as an ischemic palsy of the seventh cranial nerve. It is sympathetic paralysis, apparently due to a vasoconstriction of the arterioles of the peripheral perineural vascular channels of the seventh cranial nerve.1 There is usually a history of exposure to cold or draft on the affected side, although many patients will not recall such incidence of exposure. It has been implied that a hyperactivity or activation of the sympathetic nervous system neuropathways will cause a vasoconstriction of the arterioles, which in many parts of the face will show no direct evidence of tissue involvement such as paleness of the underlying skin. If the small and none too plentiful arterioles of the seventh nerve are involved, the vasoconstriction will start a chain of events wherein ischemia, capillary dilatation, transudation, edema of the nerve and nerve sheath will occur, then associated loss of function, that References 1. Martin, R. C.: Symposium on Facial Paralysis: Bell's Palsy , A. M. A. Arch. Otolaryng. 55:405-409 ( (April) ) 1952.Crossref 2. Duel, A. B.: Clinical Experiences in Surgical Treatment of Facial Palsy by Autoplastic Nerve Grafts: Ballance-Duel Method , Arch. Otolaryng. 16:767-788 ( (Dec.) ) 1932.Crossref 3. Mettler, F. A.: Neuroanatomy , Ed. 2, St. Louis, The C. V. Mosby Company, 1948, pp. 240-241. 4. Skolnik, E. M.: Electrodiagnosis of Lesions of Facial Nerve , J. Internat. Coll. Surgeons 23:371-380 ( (March) ) 1955. 5. Sullivan, J. A., and Smith, J. B.: Otological Concept of Bell's Palsy and Its Treatment , Ann. Otol. Rhin. & Laryng. 59:1148-1170 ( (Dec.) ) 1950. 6. Skinner, D. A.: Histamine in Bell's Palsy , Ophth. Tr. Am. Acad. 56:283-286 ( (March) -April) 1952. 7. Good, R. P.: Histamine in Bell's Palsy , Indiana Acad. Ophth. , pp. 1-5, 1954. 8. Hilger, J. A.: The Nature of Bell's Palsy , Laryngoscope 59:228-235 ( (March) ) 1949. 9. Hall, A.: Pathology of Bell's Palsy , A. M. A. Arch. Otolaryng. 54:475-477 ( (Nov.) ) 1951.

Journal

A.M.A. Archives of OtolaryngologyAmerican Medical Association

Published: Jul 1, 1958

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