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N-BUTANOL: ITS USE IN CONTROL OF POSTOPERATIVE PAIN IN OTORHINOLARYNGOLOGICAL SURGERY

N-BUTANOL: ITS USE IN CONTROL OF POSTOPERATIVE PAIN IN OTORHINOLARYNGOLOGICAL SURGERY Abstract PAIN has always constituted a major problem confronting the medical profession, and methods for its satisfactory control have been explored by innumerable research and clinical investigators. The otorhinolaryngological surgeon is constantly aware of this problem in patients with various diseases in the head, neck and chest, as well as in patients after many different operative procedures. He is therefore interested in any field of research from which he can obtain assistance in his efforts to alleviate pain. The purpose of this investigation was to determine the clinical significance of a new concept regarding the pathogenesis of pain in operative wounds and to determine the relief from pain obtainable through the therapeutic application of certain aspects of this concept. For this purpose, a study was made of the relief from pain obtained in several large groups of patients from the surgical wards of the ear, nose and throat service and the References 1. Revici, E.: The Pathogenesis of the Painful Focus , Pasteur 1:33, 1942 2. Considerations Concerning the Biology of the Painful Focus , Rev. de l'Inst. Franç. de l'Amerique latine 1:114, 1945. 3. Revici, E.; Stoopen, E.; Frenk, E., and Ravich, R. A.: The Relation of Pain to Local Physico-Chemical Changes , Bull. Inst. Appl. Biol. 1:21, 1949. 4. Stoopen, E.: Considerations About the Pathogenesis of Painful Foci , Pasteur 2:73, 1944. 5. Turner, S.: Contributions Concerning the Biology of Painful Foci , Policlinico (sez. prat.) 53:1168, 1946. 6. Revici, E., and Ravich, R. A.: The Painful Focus: I. Physiological and Pathological Pain , Bull. Inst. Appl. Biol. 1:12, 1949. 7. Revici, E.; Huesca-Mejia, C., and Ravich, R. A.: Correlation Between pH of Urine and Blood Titrimetric Alkalinity , Bull. Inst. Appl. Biol. 1:39, 1949. 8. Mariani, J.: The Liposides: II. A Study of Their Physico-Mathematical Properties , Bull. Inst. Appl. Biol. 1:62, 1949. 9. Revici, E.: The Liposides: I. A New Systematization of Polar-Nonpolar Substances , Bull. Inst. Appl. Biol. 1:49, 1949. 10. The chemical referred to in this paper is 1-butanol, which is the name approved by the International Union of Chemistry. The following synonyms are occasionally used and accepted: n-butanol, n-butyl alcohol, primary butanol and primary butyl alcohol. 11. Ravich, R. A., and Revici, E.: Toxicity of n-Butyl Alcohol, to be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Otolaryngology American Medical Association

N-BUTANOL: ITS USE IN CONTROL OF POSTOPERATIVE PAIN IN OTORHINOLARYNGOLOGICAL SURGERY

A.M.A. Archives of Otolaryngology , Volume 52 (4) – Oct 1, 1950

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References (9)

Publisher
American Medical Association
Copyright
Copyright © 1950 American Medical Association. All Rights Reserved.
ISSN
0096-6894
DOI
10.1001/archotol.1950.00700030573004
Publisher site
See Article on Publisher Site

Abstract

Abstract PAIN has always constituted a major problem confronting the medical profession, and methods for its satisfactory control have been explored by innumerable research and clinical investigators. The otorhinolaryngological surgeon is constantly aware of this problem in patients with various diseases in the head, neck and chest, as well as in patients after many different operative procedures. He is therefore interested in any field of research from which he can obtain assistance in his efforts to alleviate pain. The purpose of this investigation was to determine the clinical significance of a new concept regarding the pathogenesis of pain in operative wounds and to determine the relief from pain obtainable through the therapeutic application of certain aspects of this concept. For this purpose, a study was made of the relief from pain obtained in several large groups of patients from the surgical wards of the ear, nose and throat service and the References 1. Revici, E.: The Pathogenesis of the Painful Focus , Pasteur 1:33, 1942 2. Considerations Concerning the Biology of the Painful Focus , Rev. de l'Inst. Franç. de l'Amerique latine 1:114, 1945. 3. Revici, E.; Stoopen, E.; Frenk, E., and Ravich, R. A.: The Relation of Pain to Local Physico-Chemical Changes , Bull. Inst. Appl. Biol. 1:21, 1949. 4. Stoopen, E.: Considerations About the Pathogenesis of Painful Foci , Pasteur 2:73, 1944. 5. Turner, S.: Contributions Concerning the Biology of Painful Foci , Policlinico (sez. prat.) 53:1168, 1946. 6. Revici, E., and Ravich, R. A.: The Painful Focus: I. Physiological and Pathological Pain , Bull. Inst. Appl. Biol. 1:12, 1949. 7. Revici, E.; Huesca-Mejia, C., and Ravich, R. A.: Correlation Between pH of Urine and Blood Titrimetric Alkalinity , Bull. Inst. Appl. Biol. 1:39, 1949. 8. Mariani, J.: The Liposides: II. A Study of Their Physico-Mathematical Properties , Bull. Inst. Appl. Biol. 1:62, 1949. 9. Revici, E.: The Liposides: I. A New Systematization of Polar-Nonpolar Substances , Bull. Inst. Appl. Biol. 1:49, 1949. 10. The chemical referred to in this paper is 1-butanol, which is the name approved by the International Union of Chemistry. The following synonyms are occasionally used and accepted: n-butanol, n-butyl alcohol, primary butanol and primary butyl alcohol. 11. Ravich, R. A., and Revici, E.: Toxicity of n-Butyl Alcohol, to be published.

Journal

A.M.A. Archives of OtolaryngologyAmerican Medical Association

Published: Oct 1, 1950

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