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TREATMENT OF COMPLICATED ACUTE SINUSITIS WITH PENICILLIN

TREATMENT OF COMPLICATED ACUTE SINUSITIS WITH PENICILLIN Abstract IT IS our purpose in this paper to present and discuss the treatment of a patient who had acute sinusitis which spread to the extraocular tissues and the blood stream, with possibly early involvement of the surrounding bone and irritation of the meninges. Before the advent of penicillin therapy, acute sinusitis complicated by orbital cellulitis, bacteremia, thrombosis of the cavernous sinus or secondary meningitis was accompanied by a high mortality rate. The administration of sulfonamide compounds, with or without operative intervention, while of a certain value, frequently left much to be desired. REPORT OF A CASE A white man aged 23 entered the hospital with complaints of severe headaches and swelling of the left eye. The latter was of only four hours' duration. For one month he had suffered from attacks of frontal headaches, which he was told resulted from sinus disease. He was treated with a solution of a References 1. Kirby, W. M. M., and Hepp, V. E.: Treatment of Osteomyelitis of the Facial Bones with Penicillin , J. A. M. A. 125:1019 ( (Aug. 12) ) 1944.Crossref 2. Crowe, S. J.: The Local Use of Sulfadiazine Solution, Radon, Tyrothricin and Penicillin in Otolaryngology , Ann. Otol., Rhin. & Laryng. 53:227 ( (June) ) 1944. 3. Keefer, C. S.; Blake, F. G.; Marshall, E. K., Jr.; Lockwood, J. S., and Wood, W. B., Jr.: Penicillin in the Treatment of Infections , J. A. M. A. 122:1217 ( (Aug. 28) ) 1943. 4. Lyons, C.: Penicillin Therapy of Surgical Infections in the U. S. Army , J. A. M. A. 123:1011 ( (Dec. 18) ) 1943. 5. Sloane, H. O.: Orbital Cellulitis Treated Successfully with Penicillin , J. A. M. A. 126:164 ( (Sept. 16) ) 1944. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

TREATMENT OF COMPLICATED ACUTE SINUSITIS WITH PENICILLIN

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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1946 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1946.00680050313007
Publisher site
See Article on Publisher Site

Abstract

Abstract IT IS our purpose in this paper to present and discuss the treatment of a patient who had acute sinusitis which spread to the extraocular tissues and the blood stream, with possibly early involvement of the surrounding bone and irritation of the meninges. Before the advent of penicillin therapy, acute sinusitis complicated by orbital cellulitis, bacteremia, thrombosis of the cavernous sinus or secondary meningitis was accompanied by a high mortality rate. The administration of sulfonamide compounds, with or without operative intervention, while of a certain value, frequently left much to be desired. REPORT OF A CASE A white man aged 23 entered the hospital with complaints of severe headaches and swelling of the left eye. The latter was of only four hours' duration. For one month he had suffered from attacks of frontal headaches, which he was told resulted from sinus disease. He was treated with a solution of a References 1. Kirby, W. M. M., and Hepp, V. E.: Treatment of Osteomyelitis of the Facial Bones with Penicillin , J. A. M. A. 125:1019 ( (Aug. 12) ) 1944.Crossref 2. Crowe, S. J.: The Local Use of Sulfadiazine Solution, Radon, Tyrothricin and Penicillin in Otolaryngology , Ann. Otol., Rhin. & Laryng. 53:227 ( (June) ) 1944. 3. Keefer, C. S.; Blake, F. G.; Marshall, E. K., Jr.; Lockwood, J. S., and Wood, W. B., Jr.: Penicillin in the Treatment of Infections , J. A. M. A. 122:1217 ( (Aug. 28) ) 1943. 4. Lyons, C.: Penicillin Therapy of Surgical Infections in the U. S. Army , J. A. M. A. 123:1011 ( (Dec. 18) ) 1943. 5. Sloane, H. O.: Orbital Cellulitis Treated Successfully with Penicillin , J. A. M. A. 126:164 ( (Sept. 16) ) 1944.

Journal

Archives of Otolaryngology – American Medical Association

Published: Mar 1, 1946

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