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ACUTE MASTOIDITIS MASKED BY TREATMENT WITH SULFONAMIDE COMPOUNDS: CLINICOPATHOLOGIC CONSIDERATIONS

ACUTE MASTOIDITIS MASKED BY TREATMENT WITH SULFONAMIDE COMPOUNDS: CLINICOPATHOLOGIC CONSIDERATIONS Abstract Much has been written in the past few years attesting to the general use of sulfanilamide and its derivatives in acute pathologic conditions of the ear. As conservative therapeutic agents in the treatment of purulent otitis media and mastoiditis the status of these compounds is still debatable. Fenton1 asserted that sulfanilamide was an invaluable agent and expressed the belief that operation on many "red hot" ears has been avoided by its use. Babcock2 stated that its effect in the treatment of acute otitis media is overrated. Bowers3 expressed the opinion that it increases the chance of prompt resolution by 50 per cent and decreases the chance of operation by 50 per cent. Scal4 saw no value in the drug if bone destruction exists, and Maybaum and associates5 reserved it for the treatment of serious complications. There is common agreement among Fenton,1 Maybaum and associates,5 Seal,4 Converse,6 Bowers,3 Lillie,7 Babcock,2 Kopetzky8 References 1. Fenton, R. A.: Sulfanilamide in Otolaryngology: Some Personal Experiences , Ann. Otol., Rhin. & Laryng. 48:17 ( (March) ) 1939. 2. Babcock, J. W.: Role of Sulfanilamide in the Treatment of Acute Otitis Media , Arch. Otolaryng. 32:246 ( (Aug.) ) 1940. 3. Bowers, W. C.: Observations on Seven Hundred and Ninety-Three Cases of Acute Purulent Otitis Media , J. A. M. A. 115:178 ( (July 20) ) 1940. 4. Scal, J. C.: Evaluation of Sulfanilamide Therapy in Acute Otitis Media and Mastoiditis , New York State J. Med. 39:1790 ( (Sept. 15) ) 1939. 5. Maybaum, J. L.; Snyder, E. R., and Coleman, L. L.: Experiences with Sulfanilamide Therapy for Otogenous Infections , Arch. Otolaryng. 30:557 (Oct.) 1939 6. The Value of Sulfanilamide in Otogenous Infections , J. A. M. A. 112:2589 ( (June 24) ) 1939. 7. Converse, J. M.: Recurrence of Otitic Infections Due to the Beta-Hemolytic Streptococcus Following Inadequate Sulfanilamide Therapy , J. A. M. A. 113:1383 ( (Oct. 7) ) 1939. 8. Lillie, H. I.: Treatment of Acute and Chronic Suppurative Otitis Media , J. A. M. A. 115:506 ( (Aug. 17) ) 1940. 9. Kopetzky, S. J.: Purulent Otitis Media, Mastoiditis, Sinus Thrombosis and Suppurations of the Petrous Pyramid , Arch. Otolaryng. 32:962 ( (Nov.) ) 1940. 10. Maxwell, J. H.: The Sulfonamide Drugs in the Treatment of Acute Suppurations of the Middle Ear and Mastoid , Surg., Gynec. & Obst. 74:573 ( (Feb.) ) 1942. 11. Galloway, T. C.: Chemotherapy , Arch. Otolaryng. 30:901 ( (Dec.) ) 1939. 12. Williams, H. L.; Brown, A. E.; Herrell, W. E., and Ralph, R. D.: Sulfonamide Therapy for Acute Otitis Media and Mastoiditis , Ann. Otol., Rhin. & Laryng. 50:336 ( (June) ) 1941. 13. Ballenger, E. G.; Elder, O. F.; McDonald, H. P., and Coleman, R. C., Jr.: Failures in the Treatment of Urinary Tract Infections with Sulfanilamide , J. A. M. A. 112:1569 ( (April 22) ) 1939. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

ACUTE MASTOIDITIS MASKED BY TREATMENT WITH SULFONAMIDE COMPOUNDS: CLINICOPATHOLOGIC CONSIDERATIONS

GILMORE, GOODLATTE B.
Archives of Otolaryngology , Volume 37 (6) – Jun 1, 1943
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References (15)

Publisher
American Medical Association
Copyright
Copyright © 1943 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1943.00670030800003
Publisher site
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Abstract

Abstract Much has been written in the past few years attesting to the general use of sulfanilamide and its derivatives in acute pathologic conditions of the ear. As conservative therapeutic agents in the treatment of purulent otitis media and mastoiditis the status of these compounds is still debatable. Fenton1 asserted that sulfanilamide was an invaluable agent and expressed the belief that operation on many "red hot" ears has been avoided by its use. Babcock2 stated that its effect in the treatment of acute otitis media is overrated. Bowers3 expressed the opinion that it increases the chance of prompt resolution by 50 per cent and decreases the chance of operation by 50 per cent. Scal4 saw no value in the drug if bone destruction exists, and Maybaum and associates5 reserved it for the treatment of serious complications. There is common agreement among Fenton,1 Maybaum and associates,5 Seal,4 Converse,6 Bowers,3 Lillie,7 Babcock,2 Kopetzky8 References 1. Fenton, R. A.: Sulfanilamide in Otolaryngology: Some Personal Experiences , Ann. Otol., Rhin. & Laryng. 48:17 ( (March) ) 1939. 2. Babcock, J. W.: Role of Sulfanilamide in the Treatment of Acute Otitis Media , Arch. Otolaryng. 32:246 ( (Aug.) ) 1940. 3. Bowers, W. C.: Observations on Seven Hundred and Ninety-Three Cases of Acute Purulent Otitis Media , J. A. M. A. 115:178 ( (July 20) ) 1940. 4. Scal, J. C.: Evaluation of Sulfanilamide Therapy in Acute Otitis Media and Mastoiditis , New York State J. Med. 39:1790 ( (Sept. 15) ) 1939. 5. Maybaum, J. L.; Snyder, E. R., and Coleman, L. L.: Experiences with Sulfanilamide Therapy for Otogenous Infections , Arch. Otolaryng. 30:557 (Oct.) 1939 6. The Value of Sulfanilamide in Otogenous Infections , J. A. M. A. 112:2589 ( (June 24) ) 1939. 7. Converse, J. M.: Recurrence of Otitic Infections Due to the Beta-Hemolytic Streptococcus Following Inadequate Sulfanilamide Therapy , J. A. M. A. 113:1383 ( (Oct. 7) ) 1939. 8. Lillie, H. I.: Treatment of Acute and Chronic Suppurative Otitis Media , J. A. M. A. 115:506 ( (Aug. 17) ) 1940. 9. Kopetzky, S. J.: Purulent Otitis Media, Mastoiditis, Sinus Thrombosis and Suppurations of the Petrous Pyramid , Arch. Otolaryng. 32:962 ( (Nov.) ) 1940. 10. Maxwell, J. H.: The Sulfonamide Drugs in the Treatment of Acute Suppurations of the Middle Ear and Mastoid , Surg., Gynec. & Obst. 74:573 ( (Feb.) ) 1942. 11. Galloway, T. C.: Chemotherapy , Arch. Otolaryng. 30:901 ( (Dec.) ) 1939. 12. Williams, H. L.; Brown, A. E.; Herrell, W. E., and Ralph, R. D.: Sulfonamide Therapy for Acute Otitis Media and Mastoiditis , Ann. Otol., Rhin. & Laryng. 50:336 ( (June) ) 1941. 13. Ballenger, E. G.; Elder, O. F.; McDonald, H. P., and Coleman, R. C., Jr.: Failures in the Treatment of Urinary Tract Infections with Sulfanilamide , J. A. M. A. 112:1569 ( (April 22) ) 1939.

Journal

Archives of Otolaryngology – American Medical Association

Published: Jun 1, 1943

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