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SODIUM MORRHUATE THERAPY FOR CHRONIC SIMPLE, VASOMOTOR AND HYPERTROPHIC FORMS OF RHINITIS

SODIUM MORRHUATE THERAPY FOR CHRONIC SIMPLE, VASOMOTOR AND HYPERTROPHIC FORMS OF RHINITIS Abstract Chronic rhinitis with engorgement or congestion of the turbinates is a common disorder. Pathologically and clinically it has been classified as turgescent, intumescent, vasomotor, hyperesthetic, allergic, hypertrophic and hyperplastic rhinitis. The variations in nomenclature are somewhat confusing. These types of rhinitis cause nasal obstruction. The chronic simple form is characterized by chronic inflammation and swelling of the soft tissues with distention of the blood sinuses of the turbinates and with a varying degree of proliferation of connective tissue, from prolonged or frequent recurrences of acute inflammation, chronic sinal disease, anatomic defects and related disorders. The mucous membrane appears swollen, smooth and reddened. Patients with rhinitis of the intumescent form complain of nasal obstruction, particularly night and morning, with frequent headaches of varying intensity. Hypertrophic rhinitis can be considered as a later form, differing from the chronic simple form by its association with an enlargement of the cellular elements of the References 1. Palmer, A.: Effect of Phenol in Hyperesthetic Rhinitis with Tissue Study of Mucosa , Ann. Otol., Rhin. & Laryng. 44:25 ( (March) ) 1935. 2. Chandler, G. F.: Hay Fever Cured by Applications of Carbolic Acid to the Nasal Mucosa , M. J. & Rec. 136:337 ( (Oct.) ) 1932. 3. Spivacke, C. A.: Vasomotor Rhinitis Treated with Pure Carbolic Acid , J. Allergy 4:408 ( (July) ) 1933. 4. Lewy, A.: Contribution to Treatment of Vasomotor Rhinitis , Laryngoscope 47:100 ( (Feb.) ) 1937. 5. Hollender, A. R., and Cottle, M. H.: Recent Advances in Treatment of Nasal Accessory Sinus Disease , Eye, Ear, Nose & Throat Monthly 5:575, 1926. 6. Demetriades, T. D.: Zur Behandlung der vasomotorischen Störungen der Nase durch Iontophorese (Rhino-Kataphorese) , Monatschr. f. Ohrenh. 61:524 ( (May) -June) 1927. 7. Warwick, H.: The Treatment of Hay Fever and Allied Conditions by Ionization , Laryngoscope 44:173 ( (March) ) 1934. 8. Hollender, A. R.: Ionization as Prolonged Palliative in Vasomotor Rhinitis , Arch. Otolaryng. 21:448 ( (April) ) 1935. 9. Sputh, C. B.: Zinc Ionization in Treatment of Rhinitis and Nasal Accessory Sinusitis , J. Indiana M. A. 24:461 ( (Sept.) ) 1931. 10. Franklin, P.: Treatment of Hay Fever by Intranasal Zinc Ionization , Brit. M. J. 1:1115 ( (June 27) ) 1931. 11. Hurd, L. M.: Treatment of Hay Fever and Hyperesthetic Rhinitis by Zinc Ionization , Arch. Otolaryng. 22:416 ( (Oct.) ) 1935. 12. Tobey, H. G.: Experiences in Ionization of Nasal Mucous Membrane , Ann. Otol., Rhin. & Laryng. 44:94 ( (March) ) 1935. 13. Bernheimer, L. B.: Zinc Ionization in Nasal Allergy , J. A. M. A. 106:1980 ( (June 6) ) 1936. 14. Smit, H. M.: Symposium on Allergic Rhinitis: Tissue Changes in Inotophoresis , Ann. Otol., Rhin. & Laryng. 45:138 ( (March) ) 1936. 15. Dean, L. W.; Linton, L. D.; Smit, H. M.; Dean, L. W., Jr., and Mahoney, C.: Treatment of Allergic Rhinitis, with Particular Reference to Ionization in Control of Chronic Vasomotor Rhinitis , J. A. M. A. 108:251 ( (Jan. 23) ) 1937. 16. Aikens, H. B.: Case of Chronic Rhinitis Treated with Radium , Canad. M. A. J. 12:897 ( (Dec.) ) 1922. 17. Scott-Brown, W. G.: Use of Radium in Allergic Rhinitis with Polypi , J. Laryng. & Otol. 53:459 ( (July) ) 1938. 18. Bernheimer, L. B.: Effect of Irradiation in Allergic Nasal Mucosa , Arch. Otolaryng. 22:165 ( (Aug.) ) 1935. 19. Glas, E.: Nasenschleimhautätzungen bei Heufieber , Wien. klin. Wchnschr. 44:944 ( (July 17) ) 1931. 20. Hitschler, W. A.: Concerning the Use of the Electric Cautery in the Nose , Ann. Otol., Rhin. & Laryng. 26:519 ( (June) ) 1917. 21. Wahrer, F. L.: Reduction of Turbinate Tissue by Medical Diathermy , Arch. Phys. Therapy 14:228 ( (April) ) 1933. 22. Fletcher, I. E., and Friedberg, S. A.: Treatment of Hypertrophic and Intumescent Rhinitis , Ann. Otol., Rhin. & Laryng. 15:73 ( (March) ) 1906. 23. Horn, H.: The Treatment of Intumescent Rhinitis by Submucous Method , Ann. Otol., Rhin. & Laryng. 17:490, 1908. 24. Beck, J. C.: Pathology and Intramural Electrocoagulation of Inferior Turbinate , Ann. Otol., Rhin. & Laryng. 39:349 ( (June) ) 1930. 25. Francis, C.: A Nasal Treatment of Hay Fever , Practitioner 132:614 ( (May) ) 1934. 26. Watson, O. A.: Use of Cautery and Escharotics , J. Oklahoma M. A. 31:227 ( (Aug.) ) 1938. 27. Hutter: Heilung eines Falles von Rhinitis nervosa durch endonasale Alkoholinjektion , Monatschr. f. Ohrenh. 58:663, 1924. 28. Metzenbaum, M.: Alcoholic Injections into Inferior Turbinates for Ameloriation of Symptoms of Common Cold, Rose Fever, Hay Fever and Hay Fever Asthma , Laryngoscope 44:182 ( (March) ) 1934. 29. Leichsenring: Behandlung allergischer Krankheiten mit Alkohol-injektion in die Nasenschleimhaut , Ztschr. f. Hals-, Nasen- u. Ohrenh. 28:220, 1931. 30. Vail, H. H.: Treatment of Hay Fever by Nasal Injections of Alcohol , Arch. Otolaryng. 18:651 ( (Nov.) ) 1933. 31. Stein, O. J.: Intranasal Injection of Alcohol in the Treatment of Hyperesthetic Rhinitis and Nasal Neuroses , Ann. Otol., Rhin. & Laryng. 31:1129 ( (Dec.) ) 1922. 32. García Ibañez, L. M.: El tratamiento conservador en las rinitis hipertroficas , Bol. Asoc. méd. de Puerto Rico 25:544 ( (Sept.) ) 1933. 33. Monson, L. P.: Treatment of Hypertrophied Inferior Turbinate by Use of Sclerosing Solutions , Arch. Otolaryng. 22:96 ( (July) ) 1935. 34. Hutchinson, C. A.: Sclerosing Submucosal Injections of Turbinates , Brit. M. J. 1:72 ( (Jan. 9) ) 1937. 35. Baer, M.: Zur Injektionsbehandlung der Rhinitis chronica hyperplastica , Monatschr. f. Ohrenh. 73:108 ( (Feb.) ) 1939. 36. Sternberg, H., and Sugar, M.: Ueber therapeutische Beeinflussung nasaler Hypersekretionen (Rhinitis vasomotoria) durch kleine Joddosen , Wien. klin. Wchnschr. 39:416 ( (April 8) ) 1926. 37. Bishop, J. R.: The Treatment of Oto-Rhinological Conditions with Free Iodine Administered Subcutaneously , Laryngoscope 43:411 ( (May) ) 1933. 38. Levine, M.: Free Iodine in Treatment of Vasomotor Rhinitis and the Symptom Complex of Sneezing and Nasal Hydrorrhea , Laryngoscope 43:39 ( (Jan.) ) 1933. 39. Meyersburg, H.: Efficiency of Subcutaneous Free Iodine Therapy , M. J. & Rec. 138:317 ( (Nov.) ) 1933. 40. The product referred to is a 5 per cent solution of sodium morrhuate with benzyl alcohol. Each cubic centimeter contains 0.05 Gm. sodium morrhuate and 0.02 Gm. benzyl alcohol in aqueous solution. 41. Fishof, F. E.: The Treatment of Vasomotor Rhinitis and Allied Conditions with Sodium Morrhuate , Arch. Otolaryng. 27:413 ( (April) ) 1938. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

SODIUM MORRHUATE THERAPY FOR CHRONIC SIMPLE, VASOMOTOR AND HYPERTROPHIC FORMS OF RHINITIS

THACKER, E. A.; HAUSER, G. H.
Archives of Otolaryngology , Volume 33 (4) – Apr 1, 1941
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References (49)

Publisher
American Medical Association
Copyright
Copyright © 1941 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1941.00660030608009
Publisher site
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Abstract

Abstract Chronic rhinitis with engorgement or congestion of the turbinates is a common disorder. Pathologically and clinically it has been classified as turgescent, intumescent, vasomotor, hyperesthetic, allergic, hypertrophic and hyperplastic rhinitis. The variations in nomenclature are somewhat confusing. These types of rhinitis cause nasal obstruction. The chronic simple form is characterized by chronic inflammation and swelling of the soft tissues with distention of the blood sinuses of the turbinates and with a varying degree of proliferation of connective tissue, from prolonged or frequent recurrences of acute inflammation, chronic sinal disease, anatomic defects and related disorders. The mucous membrane appears swollen, smooth and reddened. Patients with rhinitis of the intumescent form complain of nasal obstruction, particularly night and morning, with frequent headaches of varying intensity. Hypertrophic rhinitis can be considered as a later form, differing from the chronic simple form by its association with an enlargement of the cellular elements of the References 1. Palmer, A.: Effect of Phenol in Hyperesthetic Rhinitis with Tissue Study of Mucosa , Ann. Otol., Rhin. & Laryng. 44:25 ( (March) ) 1935. 2. Chandler, G. F.: Hay Fever Cured by Applications of Carbolic Acid to the Nasal Mucosa , M. J. & Rec. 136:337 ( (Oct.) ) 1932. 3. Spivacke, C. A.: Vasomotor Rhinitis Treated with Pure Carbolic Acid , J. Allergy 4:408 ( (July) ) 1933. 4. Lewy, A.: Contribution to Treatment of Vasomotor Rhinitis , Laryngoscope 47:100 ( (Feb.) ) 1937. 5. Hollender, A. R., and Cottle, M. H.: Recent Advances in Treatment of Nasal Accessory Sinus Disease , Eye, Ear, Nose & Throat Monthly 5:575, 1926. 6. Demetriades, T. D.: Zur Behandlung der vasomotorischen Störungen der Nase durch Iontophorese (Rhino-Kataphorese) , Monatschr. f. Ohrenh. 61:524 ( (May) -June) 1927. 7. Warwick, H.: The Treatment of Hay Fever and Allied Conditions by Ionization , Laryngoscope 44:173 ( (March) ) 1934. 8. Hollender, A. R.: Ionization as Prolonged Palliative in Vasomotor Rhinitis , Arch. Otolaryng. 21:448 ( (April) ) 1935. 9. Sputh, C. B.: Zinc Ionization in Treatment of Rhinitis and Nasal Accessory Sinusitis , J. Indiana M. A. 24:461 ( (Sept.) ) 1931. 10. Franklin, P.: Treatment of Hay Fever by Intranasal Zinc Ionization , Brit. M. J. 1:1115 ( (June 27) ) 1931. 11. Hurd, L. M.: Treatment of Hay Fever and Hyperesthetic Rhinitis by Zinc Ionization , Arch. Otolaryng. 22:416 ( (Oct.) ) 1935. 12. Tobey, H. G.: Experiences in Ionization of Nasal Mucous Membrane , Ann. Otol., Rhin. & Laryng. 44:94 ( (March) ) 1935. 13. Bernheimer, L. B.: Zinc Ionization in Nasal Allergy , J. A. M. A. 106:1980 ( (June 6) ) 1936. 14. Smit, H. M.: Symposium on Allergic Rhinitis: Tissue Changes in Inotophoresis , Ann. Otol., Rhin. & Laryng. 45:138 ( (March) ) 1936. 15. Dean, L. W.; Linton, L. D.; Smit, H. M.; Dean, L. W., Jr., and Mahoney, C.: Treatment of Allergic Rhinitis, with Particular Reference to Ionization in Control of Chronic Vasomotor Rhinitis , J. A. M. A. 108:251 ( (Jan. 23) ) 1937. 16. Aikens, H. B.: Case of Chronic Rhinitis Treated with Radium , Canad. M. A. J. 12:897 ( (Dec.) ) 1922. 17. Scott-Brown, W. G.: Use of Radium in Allergic Rhinitis with Polypi , J. Laryng. & Otol. 53:459 ( (July) ) 1938. 18. Bernheimer, L. B.: Effect of Irradiation in Allergic Nasal Mucosa , Arch. Otolaryng. 22:165 ( (Aug.) ) 1935. 19. Glas, E.: Nasenschleimhautätzungen bei Heufieber , Wien. klin. Wchnschr. 44:944 ( (July 17) ) 1931. 20. Hitschler, W. A.: Concerning the Use of the Electric Cautery in the Nose , Ann. Otol., Rhin. & Laryng. 26:519 ( (June) ) 1917. 21. Wahrer, F. L.: Reduction of Turbinate Tissue by Medical Diathermy , Arch. Phys. Therapy 14:228 ( (April) ) 1933. 22. Fletcher, I. E., and Friedberg, S. A.: Treatment of Hypertrophic and Intumescent Rhinitis , Ann. Otol., Rhin. & Laryng. 15:73 ( (March) ) 1906. 23. Horn, H.: The Treatment of Intumescent Rhinitis by Submucous Method , Ann. Otol., Rhin. & Laryng. 17:490, 1908. 24. Beck, J. C.: Pathology and Intramural Electrocoagulation of Inferior Turbinate , Ann. Otol., Rhin. & Laryng. 39:349 ( (June) ) 1930. 25. Francis, C.: A Nasal Treatment of Hay Fever , Practitioner 132:614 ( (May) ) 1934. 26. Watson, O. A.: Use of Cautery and Escharotics , J. Oklahoma M. A. 31:227 ( (Aug.) ) 1938. 27. Hutter: Heilung eines Falles von Rhinitis nervosa durch endonasale Alkoholinjektion , Monatschr. f. Ohrenh. 58:663, 1924. 28. Metzenbaum, M.: Alcoholic Injections into Inferior Turbinates for Ameloriation of Symptoms of Common Cold, Rose Fever, Hay Fever and Hay Fever Asthma , Laryngoscope 44:182 ( (March) ) 1934. 29. Leichsenring: Behandlung allergischer Krankheiten mit Alkohol-injektion in die Nasenschleimhaut , Ztschr. f. Hals-, Nasen- u. Ohrenh. 28:220, 1931. 30. Vail, H. H.: Treatment of Hay Fever by Nasal Injections of Alcohol , Arch. Otolaryng. 18:651 ( (Nov.) ) 1933. 31. Stein, O. J.: Intranasal Injection of Alcohol in the Treatment of Hyperesthetic Rhinitis and Nasal Neuroses , Ann. Otol., Rhin. & Laryng. 31:1129 ( (Dec.) ) 1922. 32. García Ibañez, L. M.: El tratamiento conservador en las rinitis hipertroficas , Bol. Asoc. méd. de Puerto Rico 25:544 ( (Sept.) ) 1933. 33. Monson, L. P.: Treatment of Hypertrophied Inferior Turbinate by Use of Sclerosing Solutions , Arch. Otolaryng. 22:96 ( (July) ) 1935. 34. Hutchinson, C. A.: Sclerosing Submucosal Injections of Turbinates , Brit. M. J. 1:72 ( (Jan. 9) ) 1937. 35. Baer, M.: Zur Injektionsbehandlung der Rhinitis chronica hyperplastica , Monatschr. f. Ohrenh. 73:108 ( (Feb.) ) 1939. 36. Sternberg, H., and Sugar, M.: Ueber therapeutische Beeinflussung nasaler Hypersekretionen (Rhinitis vasomotoria) durch kleine Joddosen , Wien. klin. Wchnschr. 39:416 ( (April 8) ) 1926. 37. Bishop, J. R.: The Treatment of Oto-Rhinological Conditions with Free Iodine Administered Subcutaneously , Laryngoscope 43:411 ( (May) ) 1933. 38. Levine, M.: Free Iodine in Treatment of Vasomotor Rhinitis and the Symptom Complex of Sneezing and Nasal Hydrorrhea , Laryngoscope 43:39 ( (Jan.) ) 1933. 39. Meyersburg, H.: Efficiency of Subcutaneous Free Iodine Therapy , M. J. & Rec. 138:317 ( (Nov.) ) 1933. 40. The product referred to is a 5 per cent solution of sodium morrhuate with benzyl alcohol. Each cubic centimeter contains 0.05 Gm. sodium morrhuate and 0.02 Gm. benzyl alcohol in aqueous solution. 41. Fishof, F. E.: The Treatment of Vasomotor Rhinitis and Allied Conditions with Sodium Morrhuate , Arch. Otolaryng. 27:413 ( (April) ) 1938.

Journal

Archives of Otolaryngology – American Medical Association

Published: Apr 1, 1941

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