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RECURRENT PARALYSIS OF THE LARYNX FOLLOWING INJECTION OF TETANUS ANTITOXIN: REPORT OF A CASE

RECURRENT PARALYSIS OF THE LARYNX FOLLOWING INJECTION OF TETANUS ANTITOXIN: REPORT OF A CASE Abstract Paralysis following the injection of antitoxin, although rare in comparison with the frequency of serotherapy, has been reported in nearly a hundred cases since it was first noted, in the early part of the century, by Gangolphe.1 In most of these cases paralysis has followed the injection of tetanus antitoxin, but other serums, such as those used in the treatment of diphtheria, scarlatina, pneumonia and meningococcic meningitis, have been implicated. Doyle,2 in a tabulation of forty-nine cases of neurologic complications of serum disease, found involvement of the brachial plexus more frequent (thirty-three cases) than that of any other portion of the nervous system. Next in frequency was isolated involvement of the radial and the optic nerve; that of the latter was first described by Mason.3 Cases of paralysis of the facial nerve, paralysis of the oculomotor nerve,4 generalized paralysis5 and involvement of the auditory nerve6 have been reported. A search References 1. Gangolphe: Névrite au cours d'un cas de tétanos traité par la sérotherapie , Lyon méd. 110:497, 1908. 2. Doyle, J. B.: Neurologic Complications of Serum Sickness , Am. J. M. Sc. 185:484 ( (April) ) 1933.Crossref 3. Mason, V. K.: Optic Neuritis in Serum Sickness , J. A. M. A. 78:88 ( (Jan. 14) ) 1922.Crossref 4. Valerio, A.: Oculomotor Paralysis After Preventive Injection of Tetanus Antitoxin , Arch. d'opht. 49:181 ( (March) ) 1932. 5. Bourguignon, G.: Grave Generalized Paralysis with Bulbar and Medullary Symptoms Following Injection of Purified Antiserum , Rev. neurol. 1:334 ( (March) ) 1931. 6. Cutter, R. D.: Auditory Nerve Involvement After Tetanus Antitoxin: First Reported Case , J. A. M. A. 106:1006 ( (March 21) ) 1936.Crossref 7. Lavrand, A.: Left Recurrent Paralysis Following Injection of Tetanus Antitoxin , J. d. sc. méd. de Lille 2:331, 1924. 8. Roger, H.; Prévot, M., and Wahl, M.: Paralysis of Abductors of Larynx and of Velum Palati Following Prophylactic Injection of Antitetanus Serum , Rev. d'oto-neuro-opht. 12:419 ( (June) ) 1934. 9. Roger, H., and Bremond, M.: Right Unilateral Paralysis of Larynx Following Prophylactic Antitetanus Injection , Rev. d'oto-neuro-opht. 12:423 ( (June) ) 1934. 10. Schauwecker, J.: Serum Sickness and Recurrent Paralysis Following Injection for Prevention of Traumatic Tetanus , Zentralbl. f. Chir. 60:1411 ( (June 17) ) 1933. 11. Imperatori, C. J.: Bilateral Abductor Paralysis of Larynx Caused by Injection of Antiserum and Its Subsequent Stenosis Due to Perichondritis: Case Report , Tr. Am. Laryng. A. 57:240, 1935. 12. Kraus, W. M., and Chaney, L. B.: Serum Disease of the Nervous System: Report of Three Cases , Arch. Neurol. & Psychiat. 37:1035 ( (May) ) 1937. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

RECURRENT PARALYSIS OF THE LARYNX FOLLOWING INJECTION OF TETANUS ANTITOXIN: REPORT OF A CASE

Archives of Otolaryngology , Volume 27 (2) – Feb 1, 1938

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References (13)

Publisher
American Medical Association
Copyright
Copyright © 1938 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1938.00650030210009
Publisher site
See Article on Publisher Site

Abstract

Abstract Paralysis following the injection of antitoxin, although rare in comparison with the frequency of serotherapy, has been reported in nearly a hundred cases since it was first noted, in the early part of the century, by Gangolphe.1 In most of these cases paralysis has followed the injection of tetanus antitoxin, but other serums, such as those used in the treatment of diphtheria, scarlatina, pneumonia and meningococcic meningitis, have been implicated. Doyle,2 in a tabulation of forty-nine cases of neurologic complications of serum disease, found involvement of the brachial plexus more frequent (thirty-three cases) than that of any other portion of the nervous system. Next in frequency was isolated involvement of the radial and the optic nerve; that of the latter was first described by Mason.3 Cases of paralysis of the facial nerve, paralysis of the oculomotor nerve,4 generalized paralysis5 and involvement of the auditory nerve6 have been reported. A search References 1. Gangolphe: Névrite au cours d'un cas de tétanos traité par la sérotherapie , Lyon méd. 110:497, 1908. 2. Doyle, J. B.: Neurologic Complications of Serum Sickness , Am. J. M. Sc. 185:484 ( (April) ) 1933.Crossref 3. Mason, V. K.: Optic Neuritis in Serum Sickness , J. A. M. A. 78:88 ( (Jan. 14) ) 1922.Crossref 4. Valerio, A.: Oculomotor Paralysis After Preventive Injection of Tetanus Antitoxin , Arch. d'opht. 49:181 ( (March) ) 1932. 5. Bourguignon, G.: Grave Generalized Paralysis with Bulbar and Medullary Symptoms Following Injection of Purified Antiserum , Rev. neurol. 1:334 ( (March) ) 1931. 6. Cutter, R. D.: Auditory Nerve Involvement After Tetanus Antitoxin: First Reported Case , J. A. M. A. 106:1006 ( (March 21) ) 1936.Crossref 7. Lavrand, A.: Left Recurrent Paralysis Following Injection of Tetanus Antitoxin , J. d. sc. méd. de Lille 2:331, 1924. 8. Roger, H.; Prévot, M., and Wahl, M.: Paralysis of Abductors of Larynx and of Velum Palati Following Prophylactic Injection of Antitetanus Serum , Rev. d'oto-neuro-opht. 12:419 ( (June) ) 1934. 9. Roger, H., and Bremond, M.: Right Unilateral Paralysis of Larynx Following Prophylactic Antitetanus Injection , Rev. d'oto-neuro-opht. 12:423 ( (June) ) 1934. 10. Schauwecker, J.: Serum Sickness and Recurrent Paralysis Following Injection for Prevention of Traumatic Tetanus , Zentralbl. f. Chir. 60:1411 ( (June 17) ) 1933. 11. Imperatori, C. J.: Bilateral Abductor Paralysis of Larynx Caused by Injection of Antiserum and Its Subsequent Stenosis Due to Perichondritis: Case Report , Tr. Am. Laryng. A. 57:240, 1935. 12. Kraus, W. M., and Chaney, L. B.: Serum Disease of the Nervous System: Report of Three Cases , Arch. Neurol. & Psychiat. 37:1035 ( (May) ) 1937.

Journal

Archives of OtolaryngologyAmerican Medical Association

Published: Feb 1, 1938

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