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An Infantile Bronchial Hemangioma Unresponsive to Propranolol Therapy

An Infantile Bronchial Hemangioma Unresponsive to Propranolol Therapy CLINICAL NOTE An Infantile Bronchial Hemangioma Unresponsive to Propranolol Therapy Case Report and Literature Review David I. Sierpina, BS; Hamad M. Chaudhary, BS; David L. Walner, MD; Gabriel Aljadeff, MD; Ira W. Dubrow, MD urrent options for treating airway hemangiomas include systemic and intralesional corticosteroids, interferon therapy, chemotherapy, use of lasers, open surgical exci- sion, tracheotomy, sleeve resection, and selective artery embolization. The signifi- 1,2 C cant rates of complications described for these methods make the discovery of a 3-9 novel therapy an attractive prospect. Several case reports and case series have recently appeared in the literature describing the use of propranolol as a highly effective option for the treatment of these airway lesions. Therefore, we reviewed the literature for information on the management of airway hemangiomas by performing a comprehensive PubMed search, focusing particularly on the use of propranolol in the treatment of airway hemangiomas, defined as occurring in the subglottis, trachea, and/or bronchi. We also describe a a 3-month-old boy with a large bronchial hemangioma that did not respond to propranolol therapy. On the day of presentation, physical ex- REPORT OF A CASE amination revealed mild to moderate res- piratory distress, 94% oxygen saturation A3-month-oldboypresentedwitha3-week on room http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Otolaryngology - Head & Neck Surgery American Medical Association

An Infantile Bronchial Hemangioma Unresponsive to Propranolol Therapy

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References (15)

Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6181
eISSN
2168-619X
DOI
10.1001/archoto.2011.67
pmid
21576565
Publisher site
See Article on Publisher Site

Abstract

CLINICAL NOTE An Infantile Bronchial Hemangioma Unresponsive to Propranolol Therapy Case Report and Literature Review David I. Sierpina, BS; Hamad M. Chaudhary, BS; David L. Walner, MD; Gabriel Aljadeff, MD; Ira W. Dubrow, MD urrent options for treating airway hemangiomas include systemic and intralesional corticosteroids, interferon therapy, chemotherapy, use of lasers, open surgical exci- sion, tracheotomy, sleeve resection, and selective artery embolization. The signifi- 1,2 C cant rates of complications described for these methods make the discovery of a 3-9 novel therapy an attractive prospect. Several case reports and case series have recently appeared in the literature describing the use of propranolol as a highly effective option for the treatment of these airway lesions. Therefore, we reviewed the literature for information on the management of airway hemangiomas by performing a comprehensive PubMed search, focusing particularly on the use of propranolol in the treatment of airway hemangiomas, defined as occurring in the subglottis, trachea, and/or bronchi. We also describe a a 3-month-old boy with a large bronchial hemangioma that did not respond to propranolol therapy. On the day of presentation, physical ex- REPORT OF A CASE amination revealed mild to moderate res- piratory distress, 94% oxygen saturation A3-month-oldboypresentedwitha3-week on room

Journal

JAMA Otolaryngology - Head & Neck Surgery – American Medical Association

Published: May 1, 2011

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