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D. Grant, J. Salassa, M. Hinni, B. Pearson, William Perry (2006)
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ORIGINAL ARTICLE A Case for Single Modality Treatment With Transoral Laser Microsurgery David G. Grant, MD; Michael L. Hinni, MD; John R. Salassa, MD; William C. Perry, PA-C; Richard E. Hayden, MD; John D. Casler, MD Objective: To demonstrate the role of transoral laser mi- Results: Over the mean follow-up period of 44 crosurgery(TLM)inthetreatmentoforopharyngealcancer. months, 66 of 69 patients had no disease recurrence at the primary site. The 5-year local control estimate was Design: A 2-center retrospective case series analysis. 94%. The mean duration of hospitalization was 3 days. There were no major complications relating to TLM. Setting: Two tertiary care medical centers. No patient required a permanent feeding or tracheos- tomy tube. For stage I, II, and III disease, the 5-year Patients: The study population comprised 69 patients Kaplan-Meier estimates of locoregional control were with previously untreated select T1 to T3, N0 to N2 squa- 90%, 73%, and 70%, respectively. The 5-year overall mous cell carcinoma of the oropharynx, of whom 44 survival estimate was 86%. (74%) had no indication for adjuvant RT and 25 (36%) had an indication for adjuvant RT to the neck alone but Conclusions: Transoral laser microsurgery alone with declined radiotherapy. The primary tumor
JAMA Otolaryngology - Head & Neck Surgery – American Medical Association
Published: Dec 1, 2009
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