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ORIGINAL ARTICLE Complications That Affect Postlaryngectomy Voice Restoration Primary Surgery vs Salvage Surgery Heather M. Starmer, MA; Stacey L. Ishman, MD; Paul W. Flint, MD; Nasir I. Bhatti, MD, MHS; Jeremy Richmon, MD; Wayne Koch, MD; Kimberly Webster, MA; Ralph Tufano, MD; Christine G. Gourin, MD Objective: To assess the effect of primary treatment on Of the 81 patients who underwent primary surgery, tracheoesophageal voice prosthesis (TEP) complications. 81% (n=66) underwent adjuvant therapy with postop- erative radiotherapy or chemoradiotherapy. The inci- Design: Retrospective cohort study. dence of leakage around the prosthesis, prosthesis dis- lodgement, and size changes 6 months or longer after laryngectomy were significantly higher for patients who Setting: The Johns Hopkins Medical Institutions, Bal- required salvage total laryngectomy after chemoradio- timore, Maryland. therapy or radiotherapy (P.05). In addition, signifi- cantly more patients who underwent salvage total lar- Patients: Patients who underwent total laryngectomy yngectomy required extended laryngectomy or free and TEP between January 1, 1998, and December 31, tissue reconstruction. 2008, were divided into 3 subgroups according to pri- mary treatment: surgery (n=81), radiotherapy (n=61), Conclusions: Voice prosthesis complications are more and chemoradiotherapy (n=32). frequently encountered in those who require salvage lar- yngectomy. Understanding the potential for
JAMA Otolaryngology - Head & Neck Surgery – American Medical Association
Published: Nov 1, 2009
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