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ORIGINAL ARTICLE Duration-Related Efficacy of Postoperative Antibiotics Following Pediatric Tonsillectomy A Prospective, Randomized, Placebo-Controlled Trial Paul E. Johnson, MD; Scott M. Rickert, MD; Jacqueline Jones, MD Objective: To determine whether a 3-day course of post- ated his or her usual diet and level of activity, and medi- operative antibiotics is as effective as a 7-day course in cal treatment for oral hemorrhage or dehydration. reducing pain and reducing time to resumption of a nor- mal diet and level of activity following pediatric tonsil- Results: Of the 49 patients, 26 were randomized to re- lectomy. ceive 7 days of postoperative antibiotics (group A) and 23 to receive 3 days of antibiotics, followed by 4 days of Design : A prospective, randomized, placebo- placebo (group B). Results were obtained for 47 of the controlled trial. enrolled patients (96%). No statistically significant dif- ference was noted between the 2 groups with regard to Setting: Academic medical center. postoperative pain or time to resumption of a normal diet and level of activity. Patients: Forty-nine patients were enrolled in the study. Preoperative demographic information was obtained. Conclusion: A 3-day course of antibiotics following pe- diatric tonsillectomy is as effective as a 7-day course with
JAMA Otolaryngology - Head & Neck Surgery – American Medical Association
Published: Oct 1, 2009
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