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ORIGINAL ARTICLE Treatment of Postviral Olfactory Loss With Glucocorticoids, Ginkgo biloba, and Mometasone Nasal Spray Beom Seok Seo, MD; Hyun Jong Lee, MD; Ji-Hun Mo, MD; Chul Hee Lee, MD; Chae-Seo Rhee, MD; Jeong-Whun Kim, MD, PhD Objective: To analyze the efficacy of treating postviral The mean (SD) BTT score changes were 1.4 (2.2) in the olfactory loss with glucocorticoids, Ginkgo biloba, and mo- monotherapy group and 2.2 (2.9) in the combination metasone furoate nasal spray. therapy group (P=.22). The mean (SD) CCSIT score changes were 0.9 (1.7) in the monotherapy group and Design: Randomized trial. 1.9 (2.7) in the combination therapy group (P=.11). On the BTT, the treatment response (defined as a score in- Setting: Academic research. crease of 3) rates were 32% (9 of 28) in the mono- therapy group and 37% (16 of 43) in the combination Patients: Seventy-one patients who were diagnosed as therapy group (P=.66), and the odds ratio was 1.25 (95% having postviral olfactory loss. confidence interval, 0.46-3.42). On the CCSIT, the treat- ment response rates were 14% (4 of 28) in the mono- Main Outcome Measures: All patients underwent ol- therapy group and 33% (14 of 43) in the combination factory function
JAMA Otolaryngology - Head & Neck Surgery – American Medical Association
Published: Oct 1, 2009
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