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ORIGINAL ARTICLE The Bacteriology of Chronic Rhinosinusitis With and Without Nasal Polyps Andrea Niederfuhr; Hanspeter Kirsche, MD; Herbert Riechelmann, MD; Nele Wellinghausen, MD Objective: To compare the bacteriologic findings in eth- streptococci. Propionibacterium and Peptostreptococcus spe- moidal biopsy specimens and nasal lavage samples from cies were the most common anaerobes. Pathogenic bac- healthy control patients and from patients with chronic teria such as S aureus, Enterobacteriaceae, and Haemophi- rhinosinusitis (CRS) with nasal polyps (CRSNP) and lus influenzae were detected in biopsy specimens from 16 without nasal polyps (CRSNP−). of 31 CRSNP patients (52%), 4 of 13 CRSNP− pa- tients (31%), and 10 of 21 control patients (48%). There Design: Comparative microbiologic investigation. were no significant differences in the bacterial cultures of the biopsy specimens between the 3 patient groups Setting: University hospital. (P.30). The majority of bacteria detected in the bi- opsy specimens were also detected in the correspond- Patients: The study included 31 CRSNP patients, 13 CRSNP− patients, and 21 control patients ing lavage samples; however, in 35% of patients, patho- genic bacteria were found only in nasal lavage samples Intervention: Aerobe and anaerobe bacterial culture of and not in corresponding biopsy specimens. nasal lavage samples and biopsy
JAMA Otolaryngology–Head & Neck Surgery – American Medical Association
Published: Feb 1, 2009
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