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Effect of Adenotonsillectomy in PFAPA Syndrome

Effect of Adenotonsillectomy in PFAPA Syndrome ORIGINAL ARTICLE Greg Licameli, MD, MHCM; Jessica Jeffrey, MA; Jennifer Luz, BS; Dwight Jones, MD; Margaret Kenna, MD, MPH Objective: To assess the benefits of adenotonsillec- Results: Twenty-seven (14 female, 13 male) children with PFAPA syndrome underwent tonsillectomy with or with- tomy in the treatment of pediatric patients with PFAPA out adenoidectomy from 2004 through 2006. The length (periodic fever, aphthous ulcers, pharyngitis, and adeni- of follow-up for all patients ranged from 8 to 41 months. tis) syndrome. A total of 26 patients experienced a complete resolution of their symptoms. The 1 child who continued to have fe- Design: Prospective case series. brile episodes had fever cycles that were not regular in du- ration or interval and in hindsight was not likely a patient Setting: Tertiary care pediatric hospital. with PFAPA syndrome. Patients: Pediatric patients meeting criteria for PFAPA Conclusions: Our findings showed complete resolu- syndrome. tion of symptoms in 26 of 27 patients with PFAPA syn- drome treated surgically. Patients who meet clinical cri- Intervention: Tonsillectomy with or without adenoid- teria for PFAPA syndrome should be considered for ectomy. tonsillectomy and adenoidectomy if they do not re- spond to medical management. Main Outcome Measure: Resolution of PFAPA symptoms. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Otolaryngology–Head & Neck Surgery American Medical Association

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References (20)

Publisher
American Medical Association
Copyright
Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6181
eISSN
2168-619X
DOI
10.1001/archoto.2007.7
pmid
18283154
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Greg Licameli, MD, MHCM; Jessica Jeffrey, MA; Jennifer Luz, BS; Dwight Jones, MD; Margaret Kenna, MD, MPH Objective: To assess the benefits of adenotonsillec- Results: Twenty-seven (14 female, 13 male) children with PFAPA syndrome underwent tonsillectomy with or with- tomy in the treatment of pediatric patients with PFAPA out adenoidectomy from 2004 through 2006. The length (periodic fever, aphthous ulcers, pharyngitis, and adeni- of follow-up for all patients ranged from 8 to 41 months. tis) syndrome. A total of 26 patients experienced a complete resolution of their symptoms. The 1 child who continued to have fe- Design: Prospective case series. brile episodes had fever cycles that were not regular in du- ration or interval and in hindsight was not likely a patient Setting: Tertiary care pediatric hospital. with PFAPA syndrome. Patients: Pediatric patients meeting criteria for PFAPA Conclusions: Our findings showed complete resolu- syndrome. tion of symptoms in 26 of 27 patients with PFAPA syn- drome treated surgically. Patients who meet clinical cri- Intervention: Tonsillectomy with or without adenoid- teria for PFAPA syndrome should be considered for ectomy. tonsillectomy and adenoidectomy if they do not re- spond to medical management. Main Outcome Measure: Resolution of PFAPA symptoms.

Journal

JAMA Otolaryngology–Head & Neck SurgeryAmerican Medical Association

Published: Feb 1, 2008

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