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CLINICAL SCIENCES Peripapillary Retinal Nerve Fiber Layer Thickness Determined by Spectral-Domain Optical Coherence Tomography in Ophthalmologically Normal Eyes Hiroyo Hirasawa, MD; Atsuo Tomidokoro, MD; Makoto Araie, MD; Shinsuke Konno, MD; Hitomi Saito, MD; Aiko Iwase, MD; Motohiro Shirakashi, MD; Haruki Abe, MD; Shinji Ohkubo, MD; Kazuhisa Sugiyama, MD; Tomohiro Ootani, MD; Shoji Kishi, MD; Kenji Matsushita, MD; Naoyuki Maeda, MD; Masanori Hangai, MD; Nagahisa Yoshimura, MD Objectives: To evaluate the peripapillary distribution 2 innermost circles but positively correlated in the 3 out- of retinal nerve fiber layer thickness (RNFLT) in nor- ermost circles (PCC = −0.30 to −0.22 and 0.17 to 0.20; mal eyes using spectral-domain optical coherence to- P .005). Sex and axial length did not correlate with mography and to study potentially related factors. RNFLT (P .08). The decay slope was smallest in the tem- poral and largest in the nasal and inferior quadrants Methods: In 7 institutes in Japan, RNFLT in 7 concen- (P .001); positively correlated with disc area (PCC = 0.13 tric peripapillary circles with diameters ranging from 2.2 to 0.51; P .04); and negatively correlated with RNFLT to 4.0 mm were measured using spectral-domain opti- (PCC = −0.51 to −0.15; P .01). cal
JAMA Ophthalmology – American Medical Association
Published: Nov 1, 2010
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