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Corneal Endothelial Involvement in Pseudoexfoliation Syndrome-Reply

Corneal Endothelial Involvement in Pseudoexfoliation Syndrome-Reply Abstract In reply We thank Dr Ringvold for his interest and comments and for offering us the opportunity to reemphasize our view that, in PSX syndrome, there is indeed a specific corneal endotheliopathy or a real "PSX keratopathy," based on clinical and electron-microscopic evidence. Examining numerous eyes with PSX syndrome biomicroscopically, one of us (G.O.H.N.) has been puzzled for decades by the tendency of these eyes for early corneal endothelial decompensation occurring, eg, at only moderate rises of intraocular pressure (around 30 mm Hg) or after minor vitreous complications during cataract surgery.1 One obvious cause is the decrease in the endothelial cell count even in nonglaucomatous eyes.2 The other cause is the ultrastructural indication for endothelial damage by the direct—and, to us, very unexpected—involvement of the corneal endothelial cells in the production of PSX material. We agree that particular caution is advisable in interpreting the nature of cells adhering References 1. Naumann GOH, Erlanger Augenblätter-Group. Exfoliation syndrome as a risk factor for vitreous loss in extracapsular cataract surgery (preliminary report) . Acta Ophthalmol . 1988;66( (suppl 184) ):129-131.Crossref 2. Knorr HLJ, Jünemann A, Händel A, Naumann GOH. Morphometrische und qualitative Veränderungen des Hornhautendothels bei Pseudoexfoliationssyndrom . Fortschr Ophthalmol . 1991;88:786-789. 3. Eagle RC, Font RL, Fine BS. The basement membrane exfoliation syndrome . Arch Ophthalmol . 1979;97:510-515.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Corneal Endothelial Involvement in Pseudoexfoliation Syndrome-Reply

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1994 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1994.01090150027003
Publisher site
See Article on Publisher Site

Abstract

Abstract In reply We thank Dr Ringvold for his interest and comments and for offering us the opportunity to reemphasize our view that, in PSX syndrome, there is indeed a specific corneal endotheliopathy or a real "PSX keratopathy," based on clinical and electron-microscopic evidence. Examining numerous eyes with PSX syndrome biomicroscopically, one of us (G.O.H.N.) has been puzzled for decades by the tendency of these eyes for early corneal endothelial decompensation occurring, eg, at only moderate rises of intraocular pressure (around 30 mm Hg) or after minor vitreous complications during cataract surgery.1 One obvious cause is the decrease in the endothelial cell count even in nonglaucomatous eyes.2 The other cause is the ultrastructural indication for endothelial damage by the direct—and, to us, very unexpected—involvement of the corneal endothelial cells in the production of PSX material. We agree that particular caution is advisable in interpreting the nature of cells adhering References 1. Naumann GOH, Erlanger Augenblätter-Group. Exfoliation syndrome as a risk factor for vitreous loss in extracapsular cataract surgery (preliminary report) . Acta Ophthalmol . 1988;66( (suppl 184) ):129-131.Crossref 2. Knorr HLJ, Jünemann A, Händel A, Naumann GOH. Morphometrische und qualitative Veränderungen des Hornhautendothels bei Pseudoexfoliationssyndrom . Fortschr Ophthalmol . 1991;88:786-789. 3. Eagle RC, Font RL, Fine BS. The basement membrane exfoliation syndrome . Arch Ophthalmol . 1979;97:510-515.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Mar 1, 1994

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