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J. Harding, R. Heyningen (1988)
Drugs, including alcohol, that act as risk factors for cataract, and possible protection against cataract by aspirin-like analgesics and cyclopenthiazide.British Journal of Ophthalmology, 72
S. West, Beatriz Muñoz, Henry Newland, Edward Emmett, Hugh Taylor (1987)
Lack of evidence for aspirin use and prevention of cataracts.Archives of ophthalmology, 105 9
Early Treatment Diabetic Retinopathy Study Research Group (1991)
Grading diabetic retinopathy from stereoscopic color fundus photographs: an extension of the Modified Airlie House Classification: Early Treatment Diabetic Retinopathy Study report No. 10Ophthalmology, 98
Johanna Seddon, W. Christen, J. Manson, Julie Buring, R. Sperduto, C. Hennekens (1991)
Low-dose aspirin and risks of cataract in a randomized trial of US physicians.Archives of ophthalmology, 109 2
R. Klein, B. Klein, S. Moss (1984)
Visual impairment in diabetes.Ophthalmology, 91 1
Early Treatment Diabetic Retinopathy Study Research Group (1987)
Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study report No. 4Int Ophthalmol Clin, 27
Early Treatment Diabetic Retinopathy Study Research Group (1987)
Techniques for scatter and local photocoagulation treatment of diabetic retinopathy: Early Treatment Diabetic Retinopathy Study report No. 3Int Ophthalmol Clin, 27
Early Treatment Diabetic Retinopathy Study Research Group (1991)
Effects of aspirin treatment on diabetic retinopathy: Early Treatment Diabetic Retinopathy Study report No. 8Ophthalmology, 98
Persantine-Aspirin Reinfarction Study Research Group (1980)
Persantine and aspirin in coronary heart diseaseCirculation, 62
D. Seigel, R. Sperduto, F. Ferris (1982)
Aspirin and cataracts.Ophthalmology, 89 4
Early Treatment Diabetic Retinopathy Study Research Group (1987)
Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema: Early Treatment Diabetic Retinopathy Study report number 2Ophthalmology, 94
Early Treatment Diabetic Retinopathy Study Research Group (1985)
Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study report number 1Arch Ophthalmol, 103
D. Cox (1972)
Regression Models and Life-TablesJournal of the royal statistical society series b-methodological, 34
Aspirin Myocardial Infarction Study Research Group (1980)
A randomized, controlled trial of aspirin in persons recovered from myocardial infarctionJAMA, 243
Ederer F Cutler SJ (1958)
Maximum utilization of the life table in analyzing survivalJ Chronic Dis, 8
F. Ederer, R. Hiller, H. Taylor (1981)
Senile lens changes and diabetes in two population studies.American journal of ophthalmology, 91 3
B. Klein, R. Klein, S. Moss (1987)
Is Aspirin Use Associated With Lower Rates of Cataracts in Diabetic Individuals?Diabetes Care, 10
E. Cotlier, Y. Sharma (1981)
ASPIRIN AND SENILE CATARACTS IN RHEUMATOID ARTHRITISThe Lancet, 317
Early Treatment Diabetic Retinopathy Study Research Group (1991)
Early photocoagulation for diabetic retinopathy: ETDRS report No. 9Ophthalmology, 98
J. Stamler (1980)
Aspirin in coronary heart diseaseCirculation, 62
E. Cotlier (1981)
Senile cataracts: evidence for acceleration by diabetes and deceleration by salicylate.Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 16 3
L. Wilkins (1980)
Persantine and aspirin in coronary heart disease. The Persantine-Aspirin Reinfarction Study Research Group.Circulation, 62 3
Early Treatment Diabetic Retinopathy Study Research Group (1991)
Early Treatment Diabetic Retinopathy Study design and baseline patient characteristics: Early Treatment Diabetic Retinopathy Study report No. 7Ophthalmology, 98
Abstract • The Early Treatment Diabetic Retinopathy Study, a randomized clinical trial supported by the National Eye Institute, was designed to assess the effect of photocoagulation and aspirin in 3711 patients with mild to severe nonproliferative or early proliferative diabetic retinopathy. Although the primary goal of the study was to evaluate the effect of photocoagulation and aspirin on diabetic retinopathy, the study also provided an opportunity to evaluate the effects of aspirin on the development of cataract. No evidence showed that aspirin use reduced the risk of development of cataract requiring extraction (4.1% vs 4.3% in patients assigned to aspirin or placebo treatment, respectively; Mantel-Cox P =.77; relative risk, 1.05; 99% confidence interval, 0.73 to 1.51). Aspirin use also did not reduce the risk of less extensive but visually significant lens opacities developing (29.6% vs 28.3%; Mantel-Cox P=.76; relative risk, 0.99; 99% confidence interval, 0.85 to 1.15). Early Treatment Diabetic Retinopathy Study results do not support the hypothesis that aspirin (at a dose of 650 mg/d) reduces the risk of cataract development in this diabetic population. References 1. Ederer F, Hiller R, Taylor HR. Senile lens changes and diabetes in two population studies . Am J Ophthalmol . 1981;91:381-395. 2. Klein R, Klein BEK, Moss SE. Visual impairment in diabetes . Ophthalmology . 1984;91:1-9.Crossref 3. Cotlier E, Sharma YR. Aspirin and senile cataracts in rheumatoid arthritis . Lancet . 1981;1:338-339.Crossref 4. Cotlier E. Senile cataracts: evidence for acceleration by diabetes and deceleration by salicylate . Can J Ophthalmol . 1981;16:113-118. 5. Harding JJ, Van Heyningen R. Drugs, including alcohol, that act as risk factors for cataract, and possible protection against cataract by aspirin-like analgesics and cyclopenthiazide . Br J Ophthalmol . 1988;72:809-814.Crossref 6. Seigel D, Sperduto RD, Ferris F. Aspirin and cataracts . Ophthalmology . 1982;89:47A-49A.Crossref 7. West SK, Munoz BE, Newland HS, Emmett EA, Taylor HR. Lack of evidence for aspirin use and prevention of cataracts . Arch Ophthalmol . 1987;105:1229-1231.Crossref 8. Klein BEK, Klein R, Moss S. Is aspirin use associated with lower rates of cataracts in diabetic individuals? Diabetes Care . 1987;10:495-499.Crossref 9. Seddon JM, Christen WG, Manson JE, Buring JE, Sperduto RD, Hennenken S. Low-dose aspirin and risks of cataract in a randomized trial of US physicians . Arch Ophthalmol . 1991;109:252-255.Crossref 10. Early Treatment Diabetic Retinopathy Study Research Group. Early Treatment Diabetic Retinopathy Study design and baseline patient characteristics: Early Treatment Diabetic Retinopathy Study report No. 7 . Ophthalmology . 1991;98:741-756.Crossref 11. Early Treatment Diabetic Retinopathy Study Research Group. Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema: Early Treatment Diabetic Retinopathy Study report number 2 . Ophthalmology . 1987;94:761-774.Crossref 12. Early Treatment Diabetic Retinopathy Study Research Group. Techniques for scatter and local photocoagulation treatment of diabetic retinopathy: Early Treatment Diabetic Retinopathy Study report No. 3 . Int Ophthalmol Clin . 1987;27:254-264.Crossref 13. Early Treatment Diabetic Retinopathy Study Research Group. Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study report No. 4 . Int Ophthalmol Clin . 1987;27:265-272.Crossref 14. Early Treatment Diabetic Retinopathy Study Research Group. Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study report number 1 . Arch Ophthalmol . 1985;103:1796-1806.Crossref 15. Early Treatment Diabetic Retinopathy Study Research Group. Early photocoagulation for diabetic retinopathy: ETDRS report No. 9 . Ophthalmology . 1991;98:766-785.Crossref 16. Early Treatment Diabetic Retinopathy Study Research Group. Effects of aspirin treatment on diabetic retinopathy: Early Treatment Diabetic Retinopathy Study report No. 8 . Ophthalmology . 1991;98:757-765.Crossref 17. Cox DR. Regression models and life-tables . J R Stat Soc . 1972;34:187-220. 18. Early Treatment Diabetic Retinopathy Study Research Group. Grading diabetic retinopathy from stereoscopic color fundus photographs: an extension of the Modified Airlie House Classification: Early Treatment Diabetic Retinopathy Study report No. 10 . Ophthalmology . 1991;98:786-806.Crossref 19. Cutler SJ, Ederer F. Maximum utilization of the life table in analyzing survival . J Chronic Dis . 1958;8:699-712.Crossref 20. Coronary Drug Project Research Group. Aspirin in coronary heart disease . J Chronic Dis . 1976;29:625-642.Crossref 21. Aspirin Myocardial Infarction Study Research Group. A randomized, controlled trial of aspirin in persons recovered from myocardial infarction . JAMA . 1980;243:661-669.Crossref 22. Persantine-Aspirin Reinfarction Study Research Group. Persantine and aspirin in coronary heart disease . Circulation . 1980;62:449-461.Crossref
Archives of Ophthalmology – American Medical Association
Published: Mar 1, 1992
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