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Corneal Welding Using Hydrogen Fluoride Lasers

Corneal Welding Using Hydrogen Fluoride Lasers Abstract To the Editor. —Welding, or fusion, of tissues using laser energy was first described by Jain and Gorisch.1,2 The process involves some heat rise and apparently involves dissociation and reassociation of collagen fibrils without causing complete protein denaturation. Attempts to weld corneal or other ocular tissues have not met with success to date.3,4We report the fusion of corneal stroma in porcine cadaver eyes using two special wavelengths of the laser. The fusion occurred without the use of adhesional or accessory proteins and exhibited mechanical strength dependent on the depth of the fusion. Scleral tissue was also welded, although without the high degree of strength demonstrated by a corneal weld. To our knowledge, this is the first report of welding in corneal or scleral tissue in which significant mechanical strength was exhibited.Porcine eyes were obtained within 6 hours of slaughter. Epithelium was débrided by scraping it with References 1. Jain KK, Gorisch W. Repair of small blood vessels with the neodymium-YAG laser: a preliminary report . Surgery . 1979;85:684-688. 2. Jain KK. Sutureless microvascular anastomosis using a neodymium-YAG laser . J Microsurg . 1980;1:436-439.Crossref 3. Keates RH, Fried S, Levy SN, Morris JR. Carbon dioxide laser use in wound sealing and epikeratophakia . J Cataract Refract Surg . 1987;13:290-295.Crossref 4. Gailitis RP, Thompson KP, Ren Q, Morris J, Waring GO. Laser welding of synthetic epikeratoplasty lenticules to the cornea . Refract Corneal Surg . 1990;6:430-436. 5. Jeffers WQ. Short wavelength chemical lasers . AIAA J Aircraft . 1989;27:64-66.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

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References (7)

Publisher
American Medical Association
Copyright
Copyright © 1992 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1992.01080130014004
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor. —Welding, or fusion, of tissues using laser energy was first described by Jain and Gorisch.1,2 The process involves some heat rise and apparently involves dissociation and reassociation of collagen fibrils without causing complete protein denaturation. Attempts to weld corneal or other ocular tissues have not met with success to date.3,4We report the fusion of corneal stroma in porcine cadaver eyes using two special wavelengths of the laser. The fusion occurred without the use of adhesional or accessory proteins and exhibited mechanical strength dependent on the depth of the fusion. Scleral tissue was also welded, although without the high degree of strength demonstrated by a corneal weld. To our knowledge, this is the first report of welding in corneal or scleral tissue in which significant mechanical strength was exhibited.Porcine eyes were obtained within 6 hours of slaughter. Epithelium was débrided by scraping it with References 1. Jain KK, Gorisch W. Repair of small blood vessels with the neodymium-YAG laser: a preliminary report . Surgery . 1979;85:684-688. 2. Jain KK. Sutureless microvascular anastomosis using a neodymium-YAG laser . J Microsurg . 1980;1:436-439.Crossref 3. Keates RH, Fried S, Levy SN, Morris JR. Carbon dioxide laser use in wound sealing and epikeratophakia . J Cataract Refract Surg . 1987;13:290-295.Crossref 4. Gailitis RP, Thompson KP, Ren Q, Morris J, Waring GO. Laser welding of synthetic epikeratoplasty lenticules to the cornea . Refract Corneal Surg . 1990;6:430-436. 5. Jeffers WQ. Short wavelength chemical lasers . AIAA J Aircraft . 1989;27:64-66.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jan 1, 1992

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