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P. Lommatzsch (1983)
beta-Irradiation of choroidal melanoma with 106Ru/106Rh applicators. 16 Years' experience.Archives of ophthalmology, 101 5
Vogel M Meyer-Schwickerath G (1977)
Treatment of malignant melanomas of the choroid by photocoagulationEye, 97
Svitra PP Riedel KG (1986)
Kombinierte Hyperthermie und Protonenbestrahlung: ein neuer Weg zur behandlung des malignen Aderhautmelanoms?Fortschr Ophthalmol, 83
D. Char, D. Char, D. Char, W. Saunders, W. Saunders, W. Saunders, J. Castro, J. Castro, J. Castro, J. Quivey, J. Quivey, J. Quivey, A. Irvine, A. Irvine, A. Irvine, R. Stone, R. Stone, R. Stone, J. Crawford, J. Crawford, J. Crawford, M. Barricks, M. Barricks, M. Barricks, L. Lonn, L. Lonn, L. Lonn, G. Hilton, G. Hilton, G. Hilton, A. Schwartz, A. Schwartz, A. Schwartz, G.T.Y. Chen, G.T.Y. Chen, G.T.Y. Chen, J. Lyman, J. Lyman, J. Lyman, Michael Collier, Michael Collier, Michael Collier, H. Sulit, H. Sulit, H. Sulit, B. Straatsma, B. Straatsma, B. Straatsma, Anna Kaminski, Anna Kaminski, Anna Kaminski (1983)
Helium ion therapy for choroidal melanoma.Archives of ophthalmology, 100 6
K. Riedel, P. Svitra, J. Seddon, D. Albert, E. Gragoudas, A. Koehler, D. Coleman, J. Torpey, F. Lizzi, J. Driller (1985)
Proton beam irradiation and hyperthermia. Effects on experimental choroidal melanoma.Archives of ophthalmology, 103 12
Eric Hall, A. Giaccia (1973)
Radiobiology for the radiologist
B. Giovanella, J. Stehlin, S. Yim (1980)
CORRELATION OF THE THERMOSENSITIVITY OF CELLS TO THEIR MALIGNANT POTENTIAL *Annals of the New York Academy of Sciences, 335
Lommatzsch PK (1983)
Beta-irradiation of choroidal melanoma with ruthenium-106 applicators: 16 years' experienceArch Ophthalmol, 101
D. Coleman, F. Lizzi, S. Burgess, R. Silverman, M. Smith, J. Driller, A. Rosado, R. Ellsworth, B. Haik, D. Abramson (1986)
Ultrasonic hyperthermia and radiation in the management of intraocular malignant melanoma.American journal of ophthalmology, 101 6
W. Foulds, B. Damato (1986)
Alternatives to enucleation in the management of choroidal melanoma.Australian and New Zealand journal of ophthalmology, 14 1
Gholam Peyman, Claudio Juarez, James Diamond, M. Raichand (1984)
Ten years experience with eye wall resection for uveal malignant melanomas.Ophthalmology, 91 12
J. Augsburger, J. Gamel, V. Sardi, R. Greenberg, J. Shields, L. Brady (1986)
Enucleation vs cobalt plaque radiotherapy for malignant melanomas of the choroid and ciliary body.Archives of ophthalmology, 104 5
M. Vogel (1972)
Treatment of malignant choroidal melanomas with photocoagulation. Evaluation of 10-year follow-up data.American journal of ophthalmology, 74 1
J. Overgaard, H. Suit, A. Walker (1980)
Multifractionated hyperthermia treatment of malignant and normal tissue in vivo.Cancer research, 40 6
P. Finger, S. Packer, P. Svitra, R. Paglione, L. Anderson, J. Kim, F. Jakobiec (1985)
Thermoradiotherapy for intraocular tumors.Archives of ophthalmology, 103 10
S. Burgess, S. Chang, P. Svitra, J. Driller, F. Lizzi, D. Coleman (1985)
Effect of hyperthermia on experimental choroidal melanoma.British Journal of Ophthalmology, 69
J. François (1982)
Treatment of malignant choroidal melanomas by photocoagulation.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 184 3
Stehlin JS Giovanella BC (1980)
Correlation of the thermosensitivity of cells to their malignant potentialAnn NY Acad Sci, 80
M. Astrahan, P. Liggett, Z. Petrovich, G. Luxton (1987)
A 500 KHz localized current field hyperthermia system for use with ophthalmic plaque radiotherapy.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 3 5
Yeakeo PD Kline RW (1987)
Ocular melanoma: 1-125 plaquesMed Phys, 14
Samuel Packer, Samuel Packer (1987)
Iodine-125 radiation of posterior uveal melanoma.Ophthalmology, 94 12
H. Stallard (1966)
Radiotherapy for malignant melanoma of the choroid.British Journal of Ophthalmology, 50
B. Straatsma, S. Fine, J. Earle, B. Hawkins, M. Diener-West, Jack McLaughlin (1988)
Enucleation versus plaque irradiation for choroidal melanoma.Ophthalmology, 95 7
Jens Overgaard, H. Suit (1979)
Time-temperature relationship th hyperthermic treatment of malignant and normal tissue in vivo.Cancer research, 39 8
P. Finger, Samuel Packer, P. Svitra, Robert Paglione, J. Chess, Daniel Albert (1984)
Hyperthermic treatment of intraocular tumors.Archives of ophthalmology, 102 10
I. Brezovich, W. Atkinson, Dev Chakraborty (1984)
Temperature distributions in tumor models heated by self-regulating nickel-copper alloy thermoseeds.Medical physics, 11 2
E. Gragoudas, J. Seddon, M. Goitein, L. Verhey, J. Munzenrider, M. Urie, H. Suit, P. Blitzer, A. Koehler (1982)
Current results of proton beam irradiation of uveal melanomas.Ophthalmology, 92 2
Fine SL Straatsma BR (1988)
The COMS: enculeation versus plaque irradiation for choroidal melanomaOphthalmology, 95
L. Zimmerman, I. McLean, W. Foster (1980)
Statistical analysis of follow-up data concerning uveal melanomas, and the influence of enucleation.Ophthalmology, 87 6
Damato BE Foulds WS (1986)
Alternatives to enucleation in the management of choroidal melanomaAust NZ J Ophthalmol, 14
G. Meyer-Schwickerath, M. Vogel (1977)
Treatment of malignant melanomas of the choroid by photocoagulation.Transactions of the ophthalmological societies of the United Kingdom, 97 3
W. Dewey, L. Hopwood, S. Sapareto, L. Gerweck (1977)
Cellular responses to combinations of hyperthermia and radiation.Radiology, 123 2
F. Lambrou, M. Chilbert, W. Mieler, G. Williams, K. Olsen (1988)
A new technique for subchoroidal implantation of experimental malignant melanoma.Investigative ophthalmology & visual science, 29 6
Abstract • Hyperthermia has been combined with conventional radiation methods to achieve enhanced tumor destruction. We combined iodine 125 seeds with ferromagnetic thermoseeds in a single plaque to simultaneously deliver radiation and heat in a rabbit model of choroidal melanoma. Initially, six ferromagnetic thermoseeds were placed in parallel on a 14-mm episcleral plaque. The plaques were placed on normal rabbit eyes and on eyes containing transvitreally implanted choroidal melanoma. The heating response was assessed in both normal and tumor-containing eyes. Rigid copper-constantan and flexible Baily thermocouples were used to monitor temperature responses. The animals were subjected to an electromagnetic field of 100 kHz, with power of 1100 to 1500 W. The thermoseeds autoregulated at 48.2°C. Scleral temperatures stabilized at 45.8°C ± 0.4°C (SD), while temperatures at the base of the tumor stabilized at 43.6°C ± 0.1°C. Ferromagnetic thermoseeds were then combined with iodine 125 seeds. Similar temperature responses were recorded, and autoradiographic findings confirmed a uniform radiation distribution. Varying the amount or type of ferromagnetic material in the thermoseeds allows the delivery of heat at virtually any temperature. Ferromagnetic hyperthermia may provide a more simplified approach over currently available methods of heat delivery. References 1. Augsburger JJ, Gamel JW, Sardi VF, Greenberg RA, Shields JA, Brady LW. Enucleation versus cobalt plaque radiotherapy for malignant melanomas of the choroid and ciliary body . Arch Ophthalmol . 1986;104:655-661.Crossref 2. Straatsma BR, Fine SL, Earle JD, Hawkins BS, Diener-West M, McLaughlin JA. The COMS: enculeation versus plaque irradiation for choroidal melanoma . Ophthalmology . 1988;95:1000-1004.Crossref 3. Zimmerman LE, McLean IW, Foster WD. Statistical analysis of follow-up data concerning uveal melanomas, and the influence of enucleation . Ophthalmology . 1980;87:557-564.Crossref 4. Stallard HB. Radiotherapy for malignant melanoma of the choroid . Br J Ophthalmol . 1966;50:147-155.Crossref 5. Packer S. Iodine-125 radiation of posterior uveal melanoma . Ophthalmology . 1987;94:1621-1626.Crossref 6. Lommatzsch PK. Beta-irradiation of choroidal melanoma with ruthenium-106 applicators: 16 years' experience . Arch Ophthalmol . 1983;101:713-717.Crossref 7. Gragoudas ES, Seddon J, Goitein M, et al. Current results of proton beam irradiation of uveal melanomas . Ophthalmology . 1985;92:284-291.Crossref 8. Char DH, Saunders W, Castro JR, et al. Helium ion therapy for choroidal melanoma . Ophthalmology . 1983;90:1219-1225.Crossref 9. Foulds WS, Damato BE. Alternatives to enucleation in the management of choroidal melanoma . Aust NZ J Ophthalmol . 1986;14:19-27.Crossref 10. Peyman GA, Juarex CP, Diamond JG, Raichand M. Ten years' experience with eye wall resection for uveal malignant melanomas . Ophthalmology . 1984;91:1720-1724.Crossref 11. Meyer-Schwickerath G, Vogel M. Treatment of malignant melanomas of the choroid by photocoagulation . Eye . 1977;97:416-420. 12. Vogel MH: Treatment of malignant choroidal melanomas with photocoagulation: evaluation of ten year follow-up data . Am J Ophthalmol . 1972;74:1-11. 13. Francois J. Treatment of malignant choroidal melanomas by photocoagulation . Ophthalmologica . 1982;184:121-130.Crossref 14. Dewey WC, Hopwood LE, Sapareto SA, Gerweck LE. Cellular responses to combinations of hyperthermia and radiation . Radiology . 1977;123:463-474.Crossref 15. Hall EJ. Radiobiology for the Radiologist . 3rd ed. Philadelphia, Pa: JB Lippincott; 1988: 294-329. 16. Giovanella BC, Stehlin JS, Yim SO. Correlation of the thermosensitivity of cells to their malignant potential . Ann NY Acad Sci . 1980;80:206-214.Crossref 17. Finger PT, Packer S, Svitra PP, Paglione RW, Chess J, Albert DM. Hyperthermic treatment of intraocular tumors . Arch Ophthalmol . 1984;102:1477-1481.Crossref 18. Finger PT, Packer S, Svitra PP, et al. Thermoradiotherapy for intraocular tumors . Arch Ophthalmol . 1985;103:1574-1578.Crossref 19. Astrahan M, Liggett P, Petrovich Z, Luxton G. A 500 kHz localized current field hyperthermia system for use with ophthalmic plaque radiotherapy . Int J Hyperthermia . 1987;3:423-432.Crossref 20. Riedel KG, Svitra PP, Seddon JM, et al. Proton beam irradiation and hyperthermia: effects on experimental choroidal melanoma . Arch Ophthalmol . 1985;103:1862-1869.Crossref 21. Burgess SEP, Chang S, Svitra P, Driller J, Lizzi FL, Coleman DJ. Effect of hyperthermia on experimental choroidal melanoma . Br J Ophthalmol . 1985;69:854-860.Crossref 22. Riedel KG, Svitra PP, Albert DM, et al. Kombinierte Hyperthermie und Protonenbestrahlung: ein neuer Weg zur behandlung des malignen Aderhautmelanoms? Fortschr Ophthalmol . 1986;83:483-488. 23. Coleman DJ, Lizzi FL, Burgess SEP, et al. Ultrasonic hyperthermia and radiation in the management of intraocular malignant melanoma . Am J Ophthalmol . 1986;101:635-642. 24. Lambrou FH, Chilbert M, Mieler WF, Williams GA, Olsen K. A new technique for subchoroidal implantation of experimental malignant melanoma . Invest Ophthalmol Vis Sci 1988;29:995-998. 25. Kline RW, Yeakeo PD. Ocular melanoma: 1-125 plaques . Med Phys . 1987;14:475-478. 26. Brezovich IA, Atkinson WJ, Chakreborty DP. Temperature distributions in tumor models heated by self-regulating nickel-copper alloy thermoseeds . Med Phys . 1984;11:145-152.Crossref 27. Overgaard J, Suit HD. Time-temperature relationship in hyperthermic treatment of malignant and normal tissue in vivo . Cancer Res . 1979;39:3248-3253. 28. Overgaard J, Suit HD, Walker AM. Multifractional hyperthermia treatment of malignant and normal tissue in vivo . Cancer Res . 1980;40:2045-2050.
Archives of Ophthalmology – American Medical Association
Published: Oct 1, 1989
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