Access the full text.
Sign up today, get DeepDyve free for 14 days.
F. Polack, T. Demong, H. Santaella (1981)
Sodium hyaluronate (Healon) in keratoplasty and IOL implantation.Ophthalmology, 88 5
Miller D Stegmann R (1981)
Protective function of sodium hyaluronate in corneal transplantationJ Ocular Ther Surg, 1
R. Praus, I. Brettschneider (1975)
Glycosaminoglycans in Embryonic and Postnatal Human Cornea
R. Praus, I. Brettschneider (1971)
Glycosaminoglycans in the Developing Chicken CorneaOphthalmic Research, 2
W. Richter (1974)
Non-immunogenicity of purified hyaluronic acid preparations tested by passive cutaneous anaphylaxis.International archives of allergy and applied immunology, 47 2
Hoopes PC (1982)
Sodium hyaluronate in anterior segment surgery: A review and new use in extracapsular surgeryJ Am Intraocul Implant Soc, 8
Graether JM (1984)
Detachments of Descemet's membrane by the injection of sodium hyaluronateJ Ocular Ther Surg, 3
A. Richter, E. Ryde, E. Zetterström (1979)
Non-immunogenicity of a purified sodium hyaluronate preparation in man.International archives of allergy and applied immunology, 59 1
Berkowitz PJ (1983)
Surgical wound leaks associated with sodium hyaluronateAm J Ophthalmol, 95
P. Berkowitz (1983)
Surgical wound leaks associated with sodium hyaluronate (Healon).American journal of ophthalmology, 95 5
S. Percival (1982)
Complications from use of sodium hyaluronate (Healonid) in anterior segment surgery.British Journal of Ophthalmology, 66
Hallgren R Hakansson L (1980)
Regulation of granulocyte function by hyaluronic acidJ Clin Invest, 66
D. Metzler (1977)
Biochemistry: The Chemical Reactions of Living Cells
Percival SPB (1982)
Complications from the use of sodium hyaluronate in anterior segment surgeryBr J Ophthalmol, 66
C. Dahlgren, B. Björkstén (2009)
Effect of hyaluronic acid on polymorphonuclear leucocyte cell surface properties.Scandinavian journal of haematology, 28 5
E. Maguen, A. Nesburn, J. Macy (1984)
Combined use of sodium hyaluronate and tissue adhesive in penetrating keratoplasty of corneal perforations.Ophthalmic surgery, 15 1
J. Denlinger, E. Balazs (1980)
Replacement of the liquid vitreus with sodium hyaluronate in monkeys. I. Short-term evaluation.Experimental eye research, 31 1
Balazs EA Pape LG (1980)
The use of sodium hyaluronate in human anterior segment surgeryOphthalmology, 87
Stegmann R Miller D (1980)
Use of sodium hyaluronate in auto-corneal transplantation in rabbitsOphthalmic Surg, 11
DeMong T Polack FM (1981)
Sodium hyaluronate in keratoplasty and IOL implantationOphthalmology, 88
S. Rae, H. Edelhauser, R. Hyndiuk, E. Burd, R. Schultz (1983)
The effects of sodium hyaluronate, chondroitin sulfate, and methylcellulose on the corneal endothelium and intraocular pressure.American journal of ophthalmology, 95 3
Brettschneider I Praus R (1971)
Glycosaminoglycans in the developing chicken corneaOphthalmol Res, 2
D. Vastine, R. Weinberg, J. Sugar, P. Binder (1983)
Stripping of Descemet's membrane associated with intraocular lens implantation.Archives of ophthalmology, 101 7
S. Hayasaka, M. Sears (1978)
Distribution of acid phosphatase, beta-glucuronidase, and lysosomal hyaluronidase in the anterior segment of the rabbit eye.Investigative ophthalmology & visual science, 17 10
L. Pape, E. Balazs (1980)
The use of sodium hyaluronate (Healon) in human anterior segment surgery.Ophthalmology, 87 7
B. Toole, R. Trelstad (1971)
Hyaluronate production and removal during corneal development in the chick.Developmental biology, 26 1
Stegmann R Miller D (1980)
Use of sodium hyaluronate in anterior segment surgeryJ Am Intraocul Implant Soc, 6
Hara S Hayasaka S (1980)
Presence of lysosomal hyaluronidase in human corneoscleral tissueGraefes Arch Clin Exp Ophthalmol, 213
L. Hirst, E. Juan (1982)
Sodium hyaluronate and tissue adhesive in treating corneal perforations.Ophthalmology, 89 11
Abstract • The inadvertent injection of sodium hyaluronate (Healon) just anterior to Descemet's membrane during an extracapsular cataract extraction resulted in a corneal opacity. No extraordinary measures were taken to remove this substance. The opacity resolved over five months, with a final visual acuity of 20/25 and a reduction in specular microscopic cell density from 2,600 to 2,100/sq mm. Sodium hyaluronate was injected in an analogous manner into eight rabbit corneas. The eyes were enucleated, and histologic sections were examined 1, 5, 9, and 14 days later. Sodium hyaluronate injected just anterior to Descemet's membrane was found to incite an acute mild granulocytic response, which is followed by a macrophage invasion and ingestion of this substance. We recommend a conservative approach when the central portion of Descemet's membrane is detached by sodium hyaluronate during anterior segment surgery. References 1. Balazs EA, Miller D, Stegmann R: Viscosurgery and the use of sodium hyaluronate in intraocular lens implantation. Presented as a film at the International Congress and First Film Festival in Intraocular Lens Implantation, Cannes, France, May 1979. 2. Miller D, Stegmann R: Use of sodium hyaluronate in anterior segment surgery . J Am Intraocul Implant Soc 1980;6:13-15.Crossref 3. Pape LG, Balazs EA: The use of sodium hyaluronate in human anterior segment surgery . Ophthalmology 1980;87:699-705.Crossref 4. Hoopes PC: Sodium hyaluronate in anterior segment surgery: A review and new use in extracapsular surgery . J Am Intraocul Implant Soc 1982;8:148-154.Crossref 5. Stegmann R, Miller D: Protective function of sodium hyaluronate in corneal transplantation . J Ocular Ther Surg 1981;1:28-31. 6. Miller D, Stegmann R: Use of sodium hyaluronate in auto-corneal transplantation in rabbits . Ophthalmic Surg 1980;11:19-21. 7. Polack FM, DeMong T, Santaella H: Sodium hyaluronate in keratoplasty and IOL implantation . Ophthalmology 1981;88:425-431.Crossref 8. Hirst LW, DeJuan E: Sodium hyaluronate and tissue adhesive in treating corneal perforations . Ophthalmology 1982;89:1250-1253.Crossref 9. Maguen E, Nesburn AB, Macy JI: Combined use of sodium hyaluronate and tissue adhesive in penetrating keratoplasty of corneal perforations . Ophthalmic Surg 1984;15:55-57. 10. Percival SPB: Complications from the use of sodium hyaluronate in anterior segment surgery . Br J Ophthalmol 1982;66:714-716.Crossref 11. MacRae SM, Edelhauser HF, Hyndiuk RA, et al: The effects of sodium hyaluronate, chondroitin sulfate, and methylcellulose on the corneal endothelium and intraocular pressure . Am J Ophthalmol 1983;95:332-341. 12. Berkowitz PJ: Surgical wound leaks associated with sodium hyaluronate . Am J Ophthalmol 1983;95:714-715. 13. Graether JM: Detachments of Descemet's membrane by the injection of sodium hyaluronate . J Ocular Ther Surg 1984;3:178-181. 14. Metzler DE: Biochemistry: The Chemical Reactions of Living Cells . New York, Academic Press Inc, 1977, pp 85-86. 15. Denlinger JL, Balazs EA: Replacement of liquid vitreous with sodium hyaluronate in monkeys: I. Short term evaluation . Exp Eye Res 1980; 31:81-99.Crossref 16. Denlinger JL, El-Mofty AAM, Balazs EA: Replacement of the liquid vitreous with sodium hyaluronate in monkeys: II. Long term evaluation . Exp Eye Res 1980;31:101-117.Crossref 17. Richter AW: Non-immunogenicity of purified hyaluronic acid preparations tested by passive cutaneous anaphylaxis . Int Arch Allergy Appl Immunol 1974;47:211-217.Crossref 18. Richter AW, Ryde EM, Zetterstrom ED: Non-immunogenicity of a purified sodium hyaluronate preparation in man . Int Arch Allergy Appl Immunol 1979;59:45-48.Crossref 19. Hakansson L, Hallgren R, Venge P: Regulation of granulocyte function by hyaluronic acid . J Clin Invest 1980;66:299-305.Crossref 20. Dahlgren C, Bjorksten B: Effect of hyaluronic acid on polymorphonuclear leukocyte cell surface properties . Scand J Haematol 1982; 28:376-380.Crossref 21. Hayasaka S, Sears ML: Distribution of acid phosphatase, B-glucuronidase, and lysosomal hyaluronidase in the anterior segment of the rabbit eye . Invest Ophthalmol Vis Sci 1978;17:982-987. 22. Hayasaka S, Hara S, Shiono T, et al: Presence of lysosomal hyaluronidase in human corneoscleral tissue . Graefes Arch Clin Exp Ophthalmol 1980;213:235-238.Crossref 23. Praus R, Brettschneider I: Glycosaminoglycans in the developing chicken cornea . Ophthalmol Res 1971;2:367-373.Crossref 24. Toole BP, Trelstad RL: Hyaluronate production and removal during corneal development in the chick . Dev Biol 1971;26:28-35.Crossref 25. Praus R, Brettschneider I: Glycosaminoglycans in embryonic and post-natal human corneas . Ophthalmol Res 1975;7:452-458.Crossref 26. Vastine DW, Weinberg RS, Sugar J, et al: Stripping of Descemet's membrane associated with intraocular lens implantation . Arch Ophthalmol 1983;101:1042-1045.Crossref
Archives of Ophthalmology – American Medical Association
Published: Jun 1, 1985
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.