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Oscillatory Potentials-Reply

Oscillatory Potentials-Reply Abstract In Reply. —I agree with Dr Lachapelle that the use of a high-pass filter with a cutoff set at 100 cps might have significantly reduced the variability of our data. We chose a 20-cps cutoff in order to reproduce as closely as possible the original protocol described by Simonsen1 in his seminal work on the electroretinogram as a prognostic tool in a diabetic retinopathy. We were concerned that a failure to confirm his findings might otherwise have been attributable to modification of his protocol. At the present time, we are using digital filtering, which allows us to analyze the waveforms at a variety of different cutoff frequencies.While I agree that physiologic considerations would suggest that the OPs be looked at separately (which we have done), the analysis of our data showed that the summed amplitudes were more useful clinically, both as a predictor of retinopathy progression and for References 1. Simonsen SE: The value of the oscillatory potential in selecting juvenile diabetics at risk of developing proliferative retinopathy . Metab Pediatr Syst Ophthalmol 1981;5:55-61. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Oscillatory Potentials-Reply

Archives of Ophthalmology , Volume 103 (4) – Apr 1, 1985

Oscillatory Potentials-Reply

Abstract

Abstract In Reply. —I agree with Dr Lachapelle that the use of a high-pass filter with a cutoff set at 100 cps might have significantly reduced the variability of our data. We chose a 20-cps cutoff in order to reproduce as closely as possible the original protocol described by Simonsen1 in his seminal work on the electroretinogram as a prognostic tool in a diabetic retinopathy. We were concerned that a failure to confirm his findings might otherwise have been attributable to...
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References (2)

Publisher
American Medical Association
Copyright
Copyright © 1985 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1985.01050040022010
Publisher site
See Article on Publisher Site

Abstract

Abstract In Reply. —I agree with Dr Lachapelle that the use of a high-pass filter with a cutoff set at 100 cps might have significantly reduced the variability of our data. We chose a 20-cps cutoff in order to reproduce as closely as possible the original protocol described by Simonsen1 in his seminal work on the electroretinogram as a prognostic tool in a diabetic retinopathy. We were concerned that a failure to confirm his findings might otherwise have been attributable to modification of his protocol. At the present time, we are using digital filtering, which allows us to analyze the waveforms at a variety of different cutoff frequencies.While I agree that physiologic considerations would suggest that the OPs be looked at separately (which we have done), the analysis of our data showed that the summed amplitudes were more useful clinically, both as a predictor of retinopathy progression and for References 1. Simonsen SE: The value of the oscillatory potential in selecting juvenile diabetics at risk of developing proliferative retinopathy . Metab Pediatr Syst Ophthalmol 1981;5:55-61.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Apr 1, 1985

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