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Vitrectomy and Intravitreal Antiviral Drug Therapy in Acute Retinal Necrosis Syndrome: Report of Two Cases

Vitrectomy and Intravitreal Antiviral Drug Therapy in Acute Retinal Necrosis Syndrome: Report of... Abstract • Two patients with acute retinal necrosis were treated with vitrectomy, intravitreal infusion of acyclovir, and prophylactic scleral buckling procedures. Both patients have had an uneventful postoperative course and a recovery of visual acuity; follow-up has been at five and 14 months. There has been no sign of toxicity from the intravitreally administered acyclovir by electroretinographic or clinical criteria. References 1. Urayama A, Yamada N, Sasaki T, et al: Unilateral acute uveitis with periarteritis and detachment . Jpn J Clin Ophthalmol 1971;25:607-619. 2. Willerson D Jr, Aaberg TM, Reeser FH: Necrotizing vasoocclusive retinitis . Am J Ophthalmol 1977;84:209-219. 3. Young NJA, Bird AC: Bilateral acute retinal necrosis . Br J Ophthalmol 1978;62:581-590.Crossref 4. Price FW Jr, Schlaegel TF Jr: Bilateral acute retinal necrosis . Am J Ophthalmol 1980; 89:419-424. 5. Hayreh MMS, Kreiger AE, Straatsma BR, et al: Acute retinal necrosis , abstracted. Invest Ophthalmol Vis Sci 1978;19( (suppl) ):48. 6. Kometani J, Asayama T: A case of specific uveitis occurring acutely in the right eye . Folia Ophthalmol Jpn 1978;29:1397-1401. 7. Bando K, Kinoshita A, Mimura Y: Six cases of so-called `Kirisawa type' uveitis . Jpn J Clin Ophthalmol 1979;33:1515-1521. 8. Okinami S, Tsukahara I: Acute severe uveitis with retinal vasculitis and retinal detachment . Ophthalmologica 1979;179:276-285.Crossref 9. Martenet AC: Necrose rétinienne péripherique et decollement rétinien total d'origine vasculaire , in Cinquième Congrès de la Société Européene d'Ophtalmologie , Hamburg, West Germany, 1976. Stuttgart, West Germany, F Enke, 1978, pp 180-182. 10. Fisher JP, Lewis ML, Blumenkranz M, et al: The acute retinal necrosis syndrome: I. Clinical manifestations . Ophthalmology 1982;89:1309-1316.Crossref 11. Culbertson WW, Blumenkranz MS, Haines H, et al: The acute retinal necrosise syndrome: II. Histopathology and etiology . Ophthalmology 1982;89:1317-1325.Crossref 12. Gorman BD, Nadel AJ, Coles RS: Acute retinal necrosis . Ophthalmology 1982;89:809-814.Crossref 13. Topilow HW, Nussbaum JJ, Freeman HM, et al: Bilateral acute retinal necrosis: Clinical and ultrastructural study . Arch Ophthalmol 1982; 100:1901-1908.Crossref 14. Pulido JS, Palacio MN, Peyman GA, et al: Toxicity of intravitreal antiviral drugs . Ophthalmic Surg 1984;15:666-669. 15. Culbertson WW, Clarkson JG, Blumenkranz M, et al: Acute retinal necrosis . Am J Ophthalmol 1983;96:683-685. 16. Gardner PS, McQuillin J, Black MM, et al: Rapid diagnosis of herpes virus hominis infections in superficial lesions by immunofluorescent antibody techniques . Br Med J 1968;4:89-92.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Vitrectomy and Intravitreal Antiviral Drug Therapy in Acute Retinal Necrosis Syndrome: Report of Two Cases

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References (17)

Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1984.01040031308013
Publisher site
See Article on Publisher Site

Abstract

Abstract • Two patients with acute retinal necrosis were treated with vitrectomy, intravitreal infusion of acyclovir, and prophylactic scleral buckling procedures. Both patients have had an uneventful postoperative course and a recovery of visual acuity; follow-up has been at five and 14 months. There has been no sign of toxicity from the intravitreally administered acyclovir by electroretinographic or clinical criteria. References 1. Urayama A, Yamada N, Sasaki T, et al: Unilateral acute uveitis with periarteritis and detachment . Jpn J Clin Ophthalmol 1971;25:607-619. 2. Willerson D Jr, Aaberg TM, Reeser FH: Necrotizing vasoocclusive retinitis . Am J Ophthalmol 1977;84:209-219. 3. Young NJA, Bird AC: Bilateral acute retinal necrosis . Br J Ophthalmol 1978;62:581-590.Crossref 4. Price FW Jr, Schlaegel TF Jr: Bilateral acute retinal necrosis . Am J Ophthalmol 1980; 89:419-424. 5. Hayreh MMS, Kreiger AE, Straatsma BR, et al: Acute retinal necrosis , abstracted. Invest Ophthalmol Vis Sci 1978;19( (suppl) ):48. 6. Kometani J, Asayama T: A case of specific uveitis occurring acutely in the right eye . Folia Ophthalmol Jpn 1978;29:1397-1401. 7. Bando K, Kinoshita A, Mimura Y: Six cases of so-called `Kirisawa type' uveitis . Jpn J Clin Ophthalmol 1979;33:1515-1521. 8. Okinami S, Tsukahara I: Acute severe uveitis with retinal vasculitis and retinal detachment . Ophthalmologica 1979;179:276-285.Crossref 9. Martenet AC: Necrose rétinienne péripherique et decollement rétinien total d'origine vasculaire , in Cinquième Congrès de la Société Européene d'Ophtalmologie , Hamburg, West Germany, 1976. Stuttgart, West Germany, F Enke, 1978, pp 180-182. 10. Fisher JP, Lewis ML, Blumenkranz M, et al: The acute retinal necrosis syndrome: I. Clinical manifestations . Ophthalmology 1982;89:1309-1316.Crossref 11. Culbertson WW, Blumenkranz MS, Haines H, et al: The acute retinal necrosise syndrome: II. Histopathology and etiology . Ophthalmology 1982;89:1317-1325.Crossref 12. Gorman BD, Nadel AJ, Coles RS: Acute retinal necrosis . Ophthalmology 1982;89:809-814.Crossref 13. Topilow HW, Nussbaum JJ, Freeman HM, et al: Bilateral acute retinal necrosis: Clinical and ultrastructural study . Arch Ophthalmol 1982; 100:1901-1908.Crossref 14. Pulido JS, Palacio MN, Peyman GA, et al: Toxicity of intravitreal antiviral drugs . Ophthalmic Surg 1984;15:666-669. 15. Culbertson WW, Clarkson JG, Blumenkranz M, et al: Acute retinal necrosis . Am J Ophthalmol 1983;96:683-685. 16. Gardner PS, McQuillin J, Black MM, et al: Rapid diagnosis of herpes virus hominis infections in superficial lesions by immunofluorescent antibody techniques . Br Med J 1968;4:89-92.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Nov 1, 1984

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