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D. Char, D. Char, J. Castro, J. Castro, J. Quivey, J. Quivey, G.T.Y. Chen, G.T.Y. Chen, John Lyman, John Lyman, R. Stone, R. Stone, Alexander Irvine, Alexander Irvine, M. Barricks, M. Barricks, J. Crawford, J. Crawford, George Hilton, G. Hilton, L. Lonn, L. Lonn, Ariah Schwartz, Ariah Schwartz (1980)
Helium ion charged particle therapy for choroidal melanoma.Ophthalmology, 87 6
F. Jakobiec (1979)
A moratorium on enucleation for choroidal melanoma?American journal of ophthalmology, 87 6
H. Stallard (1966)
Radiotherapy for malignant melanoma of the choroid.British Journal of Ophthalmology, 50
S. Packer, M. Rotman, R. Fairchild, D. Albert, H. Atkins, B. Chan (1980)
Irradiation of choroidal melanoma with iodine 125 ophthalmic plaque.Archives of ophthalmology, 98 8
A. Haddow, P. Alexander (1964)
AN IMMUNOLOGICAL METHOD OF INCREASING THE SENSITIVITY OF PRIMARY SARCOMAS TO LOCAL IRRADIATION WITH X RAYS.Lancet, 1 7331
Ian Mclean, W. Foster (1978)
Does enucleation of the eye containing a malignant melanoma prevent or accelerate the dissemination of tumour cells.British Journal of Ophthalmology, 62
Lommatzsch PK (1979)
Radiotherapie der intraokularen Tumoren, insbesondere bei AderhautmelanomKlin Monatsbl Augenheilkd, 174
M. Boniuk (1979)
A crisis in the management of patients with choroidal melanoma.American journal of ophthalmology, 87 6
M. Rotman, R. Long, S. Packer, H. Moroson, Galin Ma, B. Chan (1977)
Radiation therapy of choroidal melanoma.Transactions of the ophthalmological societies of the United Kingdom, 97 3
MacFaul Pa (1977)
Local radiotherapy in the treatment of malignant melanoma of the choroid.Transactions of the ophthalmological societies of the United Kingdom, 97
Rotman M Packer S (1980)
Irradiation of choroidal melanoma with iodine 125 ophthalmic plaqueArch Opththalmol, 98
H. Freundlich (1949)
A New Beta-Ray Applicator using Fission ProductsNature, 164
McLean IW Zimmerman LE (1979)
Effect of enucleation on uveal melanomasAm J Ophthalmol, 87
Guthoff R (1980)
Modellmessungen zur Volumenbestimmung des malignen AderhautmelanomsAlbrecht Von Graefes Arch Klin Exp Ophthalmol, 214
E. Gragoudas, M. Goitein, L. Verhey, J. Munzenreider, H. Suit, A. Koehler (1980)
Proton Beam Irradiation: An Alternative to Enucleation for Intraocular MelanomasOphthalmology, 87
Lommatzsch Pk (1979)
[Radiotherapy of intraocular tumours, particularly of melanoma of the choroid (author's transl)].Klinische Monatsblatter Fur Augenheilkunde, 174
P. Lommatzsch (1974)
Treatment of choroidal melanomas with 106Ru/106Rh beta-ray applicators.Survey of ophthalmology, 19 2
L. Zimmerman, Ian LEAN (1979)
An Evaluation of Enucleation in the Management of Uveal MelanomasInternational Ophthalmology Clinics, 20
Abstract • From 1964 to 1980, 205 patients with choroidal melanoma were treated with 106Ru/106Rh β-ray applicators (8,000 to 10,000 rad at the summit of the tumor within 14 days). In 132 (64.4%) cases, this treatment was successful. Thirty-six (17.6%) had to be enucleated after irradiation and 37 died, 21 of them of metastases. Of the 132 successfully treated patients, 60 (45.5%) had flat scars and 34 (25.8%) retained a visual acuity of 0.5 to 1.5. Radiogenic late complications with damage to the retinal capillary system were the main causes of visual deterioration, especially in eyes with tumors close to the posterior pole. The survival rate of 85.1% after five years is substantially higher than that for patients who were primarily treated with enucleation. References 1. Zimmerman LE, McLean IW, Foster WD: Does enucleation of the eye containing a malignant melanoma prevent or accelerate the dissemination of tumor cells? Br J Ophthalmol 1978;62:420-425.Crossref 2. Zimmerman LE, McLean IW: Effect of enucleation on uveal melanomas . Am J Ophthalmol 1979;87:741-760. 3. Boniuk M: A crisis in the management of patients with choroidal melanoma . Am J Ophthalmol 1979;87:840-842. 4. Jakobiec FA: A moratorium on enucleation for choroidal melanoma . Am J Ophthalmol 1979;87:842-846. 5. Freundlich HF: A new beta-ray applicator using fission products . Nature 1949;164:308-310.Crossref 6. Lommatzsch PK: Treatment of choroidal melanomas with Ru-106/Rh-106 beta-ray applicators . Surv Ophthalmol 1974;19:85-100. 7. Lommatzsch PK: Radiotherapie der intraokularen Tumoren, insbesondere bei Aderhautmelanom . Klin Monatsbl Augenheilkd 1979;174:948-958. 8. Stallard HB: Radiotherapy for malignant melanoma of the choroid . Br J Ophthalmol 1966;50:147-155.Crossref 9. Guthoff R: Modellmessungen zur Volumenbestimmung des malignen Aderhautmelanoms . Albrecht Von Graefes Arch Klin Exp Ophthalmol 1980;214:139-146.Crossref 10. MacFaul PA: Local radiotherapy in the treatment of malignant melanoma of the choroid . Trans Ophthal 1977;97:421-427. 11. Packer S, Rotman M, Fairchild RG, et al: Irradiation of choroidal melanoma with iodine 125 ophthalmic plaque . Arch Opththalmol 1980;98:1453-1457.Crossref 12. Rotman M, Long RS, Packer S, et al: Radiation therapy of choroidal melanoma . Trans Ophthalmol Soc UK 1977;97:431-435. 13. Haddow A, Alexander P: An immunological method of increasing the sensitivity of primary sarcomas to local irradiation with X rays . Lancet 1964;1:452-457.Crossref 14. Gragoudas ES, Goitein M, Verhey L, et al: Proton beam irradiation: An alternative to enucleation for intraocular melanomas . Ophthalmology 1980;87:571-581.Crossref 15. Char DH, Castro JR, Quivey JM, et al: Helium ion charged particle therapy for choroidal melanoma . Ophthalmology 1980;87:565-570.Crossref
Archives of Ophthalmology – American Medical Association
Published: May 1, 1983
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