Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Helium Ion Therapy for Choroidal Melanoma

Helium Ion Therapy for Choroidal Melanoma Abstract • Forty patients with choroidal melanomas received radiation therapy with helium ion-charged particles. Thirty-six of 40 patients either remained stable or demonstrated tumor shrinkage. Seventeen of 18 patients followed up for at least one year after therapy demonstrated tumor regression, with a mean tumor shrinkage of approximately 40%. The most effective method of choroidal melanoma management is unclear. Charged-particle external-beam irradiation may be more applicable and have less ocular morbidity than either radioactive plaques or photocoagulation. References 1. Char DH: Management of small choroidal melanomas . Surv Ophthalmol 1978;22:377-386.Crossref 2. Stallard HB: Radiotherapy for malignant melanoma of the choroid . Br J Ophthalmol 1966;50:147-155.Crossref 3. Newman GH, Davidorf FH, Havener WH, et al: Conservative management of malignant melanoma . Arch Ophthalmol 1970;83:21-26.Crossref 4. Vogel M, Meyer-Schwickerath G: Results of photocoagulation treatment of malignant melanoma of the choroid , in Jakobiec FA (ed): Ocular and Adnexel Tumors . Birmingham, Ala, Aesculapius Publishing Co, 1978, pp 71-75. 5. Char DH, Lonn LE, Margolis LW: Complications of cobalt plaque therapy of choroidal melanomas . Am J Ophthalmol 1977;84:536-541. 6. Bedford MA, Bedotto C, McFaul PA: Radiation retinopathy after application of a cobalt plaque . Br J Ophthalmol 1970;54:505-509.Crossref 7. Stallard HB: Malignant melanoblastoma of the choroid . Mod Probl Ophthalmol 1968;7:16-38. 8. Lommatzsch DK: Radiotherapy der intraokularen Tumoren, insbesondere bei Aderhautmelanom . Klin Monatsbl Augenheilkd 1979;174:948-958. 9. Bedford MA: The use and abuse of cobalt plaques in the treatment of choroidal malignant melanomata . Trans Ophthalmol Soc UK 1970;93:139-143. 10. Gragoudas ES, Goitein M, Verhey L, et al: Proton beam irradiation . Ophthalmology 1980;87:571-581.Crossref 11. Char DH, Castro JR, Quivey JM, et al: Helium ion charged particle therapy for choroidal melanoma . Ophthalmology 1980;87:565-570.Crossref 12. Char DH: Metastatic choroidal melanoma . Am J Ophthalmol 1978;86:76-80. 13. Lyman GT, Howard J: Dosimetry and instrumentation for helium and heavy ions . Int J Radiat Oncol Biol Phys 1977;3:81-85.Crossref 14. Packer S, Rotman M: Radiotherapy of choroidal melanoma with iodine-125 . Ophthalmology 1980;87:582-590.Crossref 15. Char DH: Management of small choroidal melanomas . Surv Ophthalmol 1978;22:377-386.Crossref 16. Char DH: Current concepts in retinoblastoma . Ann Ophthalmol 1980;12:792-804. 17. Trott KR, von Lieven H, Kummer J, et al: The radiosensitivity of malignant melanomas: I. Experimental studies . Int J Radiat Oncol Biol Phys 1980;7:9-13.Crossref 18. Habermalz HJ: Irradiation of malignant melanoma: Experience in the past and present . Int J Radiat Oncol Biol Phys 1980;7:31-133. 19. Char DH, Stone RD, Irvine AR, et al: Diagnostic modalities in choroidal melanoma: Sensitivity, specificity, and reproducibility . Am J Ophthalmol 1980;89:223-230. 20. Constable IJ, Koehler AM, Schmidt RA: Proton irradiation of simulated ocular tumors . Invest Ophthalmol Vis Sci 1975;14:547-555. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Helium Ion Therapy for Choroidal Melanoma

Download PDF
4 pages

Loading next page...
 
/lp/american-medical-association/helium-ion-therapy-for-choroidal-melanoma-C267FiPtXC

References (28)

Publisher
American Medical Association
Copyright
Copyright © 1982 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1982.01030030943008
Publisher site
See Article on Publisher Site

Abstract

Abstract • Forty patients with choroidal melanomas received radiation therapy with helium ion-charged particles. Thirty-six of 40 patients either remained stable or demonstrated tumor shrinkage. Seventeen of 18 patients followed up for at least one year after therapy demonstrated tumor regression, with a mean tumor shrinkage of approximately 40%. The most effective method of choroidal melanoma management is unclear. Charged-particle external-beam irradiation may be more applicable and have less ocular morbidity than either radioactive plaques or photocoagulation. References 1. Char DH: Management of small choroidal melanomas . Surv Ophthalmol 1978;22:377-386.Crossref 2. Stallard HB: Radiotherapy for malignant melanoma of the choroid . Br J Ophthalmol 1966;50:147-155.Crossref 3. Newman GH, Davidorf FH, Havener WH, et al: Conservative management of malignant melanoma . Arch Ophthalmol 1970;83:21-26.Crossref 4. Vogel M, Meyer-Schwickerath G: Results of photocoagulation treatment of malignant melanoma of the choroid , in Jakobiec FA (ed): Ocular and Adnexel Tumors . Birmingham, Ala, Aesculapius Publishing Co, 1978, pp 71-75. 5. Char DH, Lonn LE, Margolis LW: Complications of cobalt plaque therapy of choroidal melanomas . Am J Ophthalmol 1977;84:536-541. 6. Bedford MA, Bedotto C, McFaul PA: Radiation retinopathy after application of a cobalt plaque . Br J Ophthalmol 1970;54:505-509.Crossref 7. Stallard HB: Malignant melanoblastoma of the choroid . Mod Probl Ophthalmol 1968;7:16-38. 8. Lommatzsch DK: Radiotherapy der intraokularen Tumoren, insbesondere bei Aderhautmelanom . Klin Monatsbl Augenheilkd 1979;174:948-958. 9. Bedford MA: The use and abuse of cobalt plaques in the treatment of choroidal malignant melanomata . Trans Ophthalmol Soc UK 1970;93:139-143. 10. Gragoudas ES, Goitein M, Verhey L, et al: Proton beam irradiation . Ophthalmology 1980;87:571-581.Crossref 11. Char DH, Castro JR, Quivey JM, et al: Helium ion charged particle therapy for choroidal melanoma . Ophthalmology 1980;87:565-570.Crossref 12. Char DH: Metastatic choroidal melanoma . Am J Ophthalmol 1978;86:76-80. 13. Lyman GT, Howard J: Dosimetry and instrumentation for helium and heavy ions . Int J Radiat Oncol Biol Phys 1977;3:81-85.Crossref 14. Packer S, Rotman M: Radiotherapy of choroidal melanoma with iodine-125 . Ophthalmology 1980;87:582-590.Crossref 15. Char DH: Management of small choroidal melanomas . Surv Ophthalmol 1978;22:377-386.Crossref 16. Char DH: Current concepts in retinoblastoma . Ann Ophthalmol 1980;12:792-804. 17. Trott KR, von Lieven H, Kummer J, et al: The radiosensitivity of malignant melanomas: I. Experimental studies . Int J Radiat Oncol Biol Phys 1980;7:9-13.Crossref 18. Habermalz HJ: Irradiation of malignant melanoma: Experience in the past and present . Int J Radiat Oncol Biol Phys 1980;7:31-133. 19. Char DH, Stone RD, Irvine AR, et al: Diagnostic modalities in choroidal melanoma: Sensitivity, specificity, and reproducibility . Am J Ophthalmol 1980;89:223-230. 20. Constable IJ, Koehler AM, Schmidt RA: Proton irradiation of simulated ocular tumors . Invest Ophthalmol Vis Sci 1975;14:547-555.

Journal

Archives of Ophthalmology – American Medical Association

Published: Jun 1, 1982

There are no references for this article.