Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Fluorescein Angiography of the Optic Disc: A Longitudinal Follow-up Study

Fluorescein Angiography of the Optic Disc: A Longitudinal Follow-up Study Abstract • A comparison of two or more disc fluorescein angiograms performed on separate occasions was done on 60 eyes of normal subjects and patients with ocular hypertension, primary open-angle glaucoma, and low-tension glaucoma. Clinically stable patients did not show any change in their disc angiographic filling patterns. Eyes that developed new visualfield defects with increased disc cupping and pallor correspondingly showed new absolute filling defects or areas of hypofluorescence. In those with established field defects, however, further changes in the visual field occurred without obvious changes in the disc fluorescein filling defect. Surgical lowering of intraocular pressure with or without decrease in disc cupping and pallor did not result in visible improvement of the disc angiographic pattern. Thus, the development of new visual-field defects is associated with changes of the circulation of the optic disc. References 1. Schwartz B: Primary open angle glaucoma , in Duane TD (ed): Clinical Ophthalmology . Hagerstown, Md, Harper & Row Publishers, 1976, pp 10-22. 2. Laatikainen L, Mantyla P: Effects of a fall in the intraocular pressure level on the peripappilary fluorescein angiogram in chronic open angle glaucoma . Acta Ophthalmol 52:625-633, 1974.Crossref 3. Spaeth GL: Fluorescein angiography: Its contribution towards understanding the mechanisms of visual loss in glaucoma . Trans Am Ophthalmol Soc 73:491-553, 1975. 4. Hayreh SS, Walker WM: Fluorescent fundus photography in glaucoma . Am J Ophthalmol 63:982-989, 1967. 5. Hitchings RA, Spaeth GL: Fluorescein angiography in glaucoma , in Cant CJ (ed): Vision and Circulation . London, Henry Kimpton Medical Publisher & Bookseller, 1976, pp 201-216. 6. Schwartz B, Rieser JC, Fishbein SL: Fluorescein angiographic defects of the optic disc in glaucoma . Arch Ophthalmol 95:1961-1974, 1977.Crossref 7. Fishbein SL, Schwartz B: Optic disc in glaucoma: Topography and extent of fluorescein filling defects . Arch Ophthalmol 95:1975-1978, 1977.Crossref 8. Tsukahara S, Nagatek S, Sugaya M, et al: Visual field defects, cup-disc ratio and fluorescein angiography in glaucomatous optic atrophy . Adv Ophthalmol 35:73-93, 1978. 9. Loebl M, Schwartz B: Fluorescein angiographic defects of the optic disc in ocular hypertension . Arch Ophthalmol 95:1980-1984, 1977.Crossref 10. Talusan ED, Schwartz B: Specificity of fluorescein angiographic defects of the optic disc in glaucoma . Arch Ophthalmol 95:2166-2175, 1977.Crossref 11. Tsukahara S: Hyperpermeable disc capillaries in glaucoma . Adv Ophthalmol 35:65-72, 1978. 12. Drance SM, Begg IS, Goldman H: Fluorescein angiography in the evaluation of focal circulatory ischemia of the optic nerve head in relation to the arcuate scotoma in glaucoma . Can J Ophthalmol 7:68-74, 1972. 13. Ben-Sira I, Loebl M, Schwartz B, et al: In vivo measurements of diffusion of fluorescein in the human optic disc nerve tissue , in Documenta Ophthalmologica Proceedings Series: International Symposium on Fluorescein Angiography . The Hague, W Junk Publishers, 1976, pp 311-314. 14. Spaeth GL: The Pathogenesis of Nerve Damage in Glaucoma: Contribution of Fluorescein Angiography . New York, Grune & Stratton Inc, 1977. 15. Hayreh SS: Color and fluorescence of the optic disc . Ophthalmologica 165:100-108, 1975.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Fluorescein Angiography of the Optic Disc: A Longitudinal Follow-up Study

Loading next page...
 
/lp/american-medical-association/fluorescein-angiography-of-the-optic-disc-a-longitudinal-follow-up-d1WK6vPGqk

References (15)

Publisher
American Medical Association
Copyright
Copyright © 1980 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1980.01020040431007
Publisher site
See Article on Publisher Site

Abstract

Abstract • A comparison of two or more disc fluorescein angiograms performed on separate occasions was done on 60 eyes of normal subjects and patients with ocular hypertension, primary open-angle glaucoma, and low-tension glaucoma. Clinically stable patients did not show any change in their disc angiographic filling patterns. Eyes that developed new visualfield defects with increased disc cupping and pallor correspondingly showed new absolute filling defects or areas of hypofluorescence. In those with established field defects, however, further changes in the visual field occurred without obvious changes in the disc fluorescein filling defect. Surgical lowering of intraocular pressure with or without decrease in disc cupping and pallor did not result in visible improvement of the disc angiographic pattern. Thus, the development of new visual-field defects is associated with changes of the circulation of the optic disc. References 1. Schwartz B: Primary open angle glaucoma , in Duane TD (ed): Clinical Ophthalmology . Hagerstown, Md, Harper & Row Publishers, 1976, pp 10-22. 2. Laatikainen L, Mantyla P: Effects of a fall in the intraocular pressure level on the peripappilary fluorescein angiogram in chronic open angle glaucoma . Acta Ophthalmol 52:625-633, 1974.Crossref 3. Spaeth GL: Fluorescein angiography: Its contribution towards understanding the mechanisms of visual loss in glaucoma . Trans Am Ophthalmol Soc 73:491-553, 1975. 4. Hayreh SS, Walker WM: Fluorescent fundus photography in glaucoma . Am J Ophthalmol 63:982-989, 1967. 5. Hitchings RA, Spaeth GL: Fluorescein angiography in glaucoma , in Cant CJ (ed): Vision and Circulation . London, Henry Kimpton Medical Publisher & Bookseller, 1976, pp 201-216. 6. Schwartz B, Rieser JC, Fishbein SL: Fluorescein angiographic defects of the optic disc in glaucoma . Arch Ophthalmol 95:1961-1974, 1977.Crossref 7. Fishbein SL, Schwartz B: Optic disc in glaucoma: Topography and extent of fluorescein filling defects . Arch Ophthalmol 95:1975-1978, 1977.Crossref 8. Tsukahara S, Nagatek S, Sugaya M, et al: Visual field defects, cup-disc ratio and fluorescein angiography in glaucomatous optic atrophy . Adv Ophthalmol 35:73-93, 1978. 9. Loebl M, Schwartz B: Fluorescein angiographic defects of the optic disc in ocular hypertension . Arch Ophthalmol 95:1980-1984, 1977.Crossref 10. Talusan ED, Schwartz B: Specificity of fluorescein angiographic defects of the optic disc in glaucoma . Arch Ophthalmol 95:2166-2175, 1977.Crossref 11. Tsukahara S: Hyperpermeable disc capillaries in glaucoma . Adv Ophthalmol 35:65-72, 1978. 12. Drance SM, Begg IS, Goldman H: Fluorescein angiography in the evaluation of focal circulatory ischemia of the optic nerve head in relation to the arcuate scotoma in glaucoma . Can J Ophthalmol 7:68-74, 1972. 13. Ben-Sira I, Loebl M, Schwartz B, et al: In vivo measurements of diffusion of fluorescein in the human optic disc nerve tissue , in Documenta Ophthalmologica Proceedings Series: International Symposium on Fluorescein Angiography . The Hague, W Junk Publishers, 1976, pp 311-314. 14. Spaeth GL: The Pathogenesis of Nerve Damage in Glaucoma: Contribution of Fluorescein Angiography . New York, Grune & Stratton Inc, 1977. 15. Hayreh SS: Color and fluorescence of the optic disc . Ophthalmologica 165:100-108, 1975.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Sep 1, 1980

There are no references for this article.