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Neurotrophic Corneal Ulcers in Diabetes Mellitus

Neurotrophic Corneal Ulcers in Diabetes Mellitus Abstract • Three patients with juvenile-onset insulin-dependent diabetes mellitus had neurotrophic keratitis and/or ulceration presumably related to their diabetes. We suggest that significant neurotrophic corneal disease can occur in diabetic patients. The neurotrophic keratitis and corneal ulcers responded to treatment. (Arch Ophthalmol 95:2193-2196, 1977) References 1. Schwartz DE: Corneal sensitivity in diabetics . Arch Ophthalmol 91:174-178, 1974.Crossref 2. Cochet P, Bonnet R: L'esthesiometrie Corneenne: Realisation et interet pratique . Bull Soc Ophtalmol Fr 61:541-550, 1961. 3. Norn MS: Dendritic keratitis: IV. Follow-up examination of corneal sensitivity . Acta Ophthalmol 48:383-395, 1970.Crossref 4. Woltman HW, Wilder RM: Diabetes mellitus: Pathologic changes in the spinal cord and peripheral nerves . Arch Intern Med 44:576-603, 1929.Crossref 5. Fagerberg SE: Studies on the pathogenesis of diabetic neuropathy: III. Diabetic neuropathy in relation to diabetic vessel complications . Acta Med Scand 157:401-406, 1957.Crossref 6. Thomas PK, Lascelles RG: The pathology of diabetic neuropathy . Q J Med 35:489-509, 1966. 7. Chopra JS, Hurwitz LJ, Montgomery DAD: The pathogenesis of sural nerve changes in diabetes mellitus . Brain 92:391-418, 1969.Crossref 8. Winegrad AI: Diabetic neuropathy . N Engl J Med 286:1261-1262, 1972.Crossref 9. Greene DA, De Jesus PV, Winegrad AI: Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes . J Clin Invest 55:1326-1336, 1975.Crossref 10. Quaranta CA: Sulla frequenza di una particolare forma di alterazione corneale in diabetici . Ateneo Parmense 25:548-555, 1954. 11. Ioli Spada G: Ulteriore contributo allo Studio della cheratodistrofia epiteliale puntata diabetica . Boll Ocul 43:775-785, 1964. 12. Scullica L, Proto F: Rilievi clinici e statistici sulla sensibilitá corneale nei diabetici . Boll Ocul 44:944-954, 1965. 13. De Haas EBH: Desiccation of cornea and conjunctiva after sensory denervation . Arch Ophthalmol 67:79-92, 1962.Crossref 14. Duke-Elder S: System of Ophthalmology . London, Henry Kimpton, 1965, vol 8, p 805. 15. Sigelman S, Friedenwald JS: Mitotic and wound-healing activities of the corneal epithelium: Effect of sensory denervation . Arch Ophthalmol 52:46-57, 1954.Crossref 16. Awasthi P, Sarbhai KP, Maheshwari BB, et al: Corneal sensations in diabetes mellitus . Trans XXII Int Congr Paris 1:402-409, 1974. 17. Mandelcorn MS, Blankenship G, Machemer R: Pars plana vitrectomy for the management of severe diabetic retinopathy . Am J Ophthalmol 81:561-570, 1976. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Neurotrophic Corneal Ulcers in Diabetes Mellitus

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References (20)

Publisher
American Medical Association
Copyright
Copyright © 1977 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1977.04450120099012
Publisher site
See Article on Publisher Site

Abstract

Abstract • Three patients with juvenile-onset insulin-dependent diabetes mellitus had neurotrophic keratitis and/or ulceration presumably related to their diabetes. We suggest that significant neurotrophic corneal disease can occur in diabetic patients. The neurotrophic keratitis and corneal ulcers responded to treatment. (Arch Ophthalmol 95:2193-2196, 1977) References 1. Schwartz DE: Corneal sensitivity in diabetics . Arch Ophthalmol 91:174-178, 1974.Crossref 2. Cochet P, Bonnet R: L'esthesiometrie Corneenne: Realisation et interet pratique . Bull Soc Ophtalmol Fr 61:541-550, 1961. 3. Norn MS: Dendritic keratitis: IV. Follow-up examination of corneal sensitivity . Acta Ophthalmol 48:383-395, 1970.Crossref 4. Woltman HW, Wilder RM: Diabetes mellitus: Pathologic changes in the spinal cord and peripheral nerves . Arch Intern Med 44:576-603, 1929.Crossref 5. Fagerberg SE: Studies on the pathogenesis of diabetic neuropathy: III. Diabetic neuropathy in relation to diabetic vessel complications . Acta Med Scand 157:401-406, 1957.Crossref 6. Thomas PK, Lascelles RG: The pathology of diabetic neuropathy . Q J Med 35:489-509, 1966. 7. Chopra JS, Hurwitz LJ, Montgomery DAD: The pathogenesis of sural nerve changes in diabetes mellitus . Brain 92:391-418, 1969.Crossref 8. Winegrad AI: Diabetic neuropathy . N Engl J Med 286:1261-1262, 1972.Crossref 9. Greene DA, De Jesus PV, Winegrad AI: Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes . J Clin Invest 55:1326-1336, 1975.Crossref 10. Quaranta CA: Sulla frequenza di una particolare forma di alterazione corneale in diabetici . Ateneo Parmense 25:548-555, 1954. 11. Ioli Spada G: Ulteriore contributo allo Studio della cheratodistrofia epiteliale puntata diabetica . Boll Ocul 43:775-785, 1964. 12. Scullica L, Proto F: Rilievi clinici e statistici sulla sensibilitá corneale nei diabetici . Boll Ocul 44:944-954, 1965. 13. De Haas EBH: Desiccation of cornea and conjunctiva after sensory denervation . Arch Ophthalmol 67:79-92, 1962.Crossref 14. Duke-Elder S: System of Ophthalmology . London, Henry Kimpton, 1965, vol 8, p 805. 15. Sigelman S, Friedenwald JS: Mitotic and wound-healing activities of the corneal epithelium: Effect of sensory denervation . Arch Ophthalmol 52:46-57, 1954.Crossref 16. Awasthi P, Sarbhai KP, Maheshwari BB, et al: Corneal sensations in diabetes mellitus . Trans XXII Int Congr Paris 1:402-409, 1974. 17. Mandelcorn MS, Blankenship G, Machemer R: Pars plana vitrectomy for the management of severe diabetic retinopathy . Am J Ophthalmol 81:561-570, 1976.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Dec 1, 1977

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