Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Optic Disc in Glaucoma: Topography and Extent of Fluorescein Filling Defects

Optic Disc in Glaucoma: Topography and Extent of Fluorescein Filling Defects Abstract • The topography and extent of localized areas of hypofluorescence or absolute filling defects of the optic discs of glaucomatous patients correlated positively with the loss of visual field. Filling defects tended to cluster at the inferior and superior poles of the optic disc and were closer to the disc margin than to the center. The location of the defects corresponded with the expected site of visual field loss. There was a positive correlation between the percent area of the filling defects and the degree of visual field loss. These observations support the concept that fluorescein filling defects of the optic disc in glaucoma represent areas of ischemia that are highly correlated with loss of visual field. (Arch Ophthalmol 95:1975-1979, 1977) References 1. Hayreh SS, Walker WM: Fluorescent fundus photography in glaucoma . Am J Ophthalmol 63:982-989, 1967. 2. Hayreh SS: Blood supply of the optic nerve head and its role in optic atrophy, glaucoma, and oedema of the optic disc . Br J Ophthalmol 53:721-748, 1969.Crossref 3. Oosterhuis JA, Gortzak-Moorstein M: Fluorescein angiography of the optic disc in galucoma . Ophthalmologica 160:331-353, 1970.Crossref 4. Raitta C, Sarmela T: Fluorescein angiography of the optic disc and the peripapillary area in chronic glaucoma . Acta Ophthalmol 48:303-308, 1970.Crossref 5. Batrachenko IP: Fluorescein angioretinography in primary glaucoma . Vestn Oftalmol 83( (3) ):22-26, 1970. 6. Karel I, Kraus H, Peleska M: Contribution to the fluoroangiographic findings in open-angle glaucoma . CS Oftalmol 31:40-46, 1975. 7. Begg IS, Drance SM, Goldman H: Fluorescein angiography in the evaluation of focal circulatory ischaemia of the optic nerve head in relation to the arcuate scotoma in glaucoma . Can J Ophthalmol 7:68-74, 1972. 8. Spaeth GL: Fluorescein angiography: Its contribution towards understanding the mechanisms of visual loss in glaucoma . Trans Am Ophthalmol Soc 73:491-553, 1975. 9. Schwartz B: New techniques for the examination of the optic disc and their clinical application . Trans Am Acad Ophthalmol Otolaryngol 81:OP 227-237, 1976. 10. Siegel S: Non Parametric Statistics for the Behavioral Services . New York, McGraw-Hill Book Co Inc, 1956. 11. Traquair HM: The nerve-fiber bundle defect . Trans Ophthalmol Soc UK 64:3-23, 1944. 12. Lynn JR: Correlation of pathogenesis, anatomy and patterns of visual field loss in glaucoma in Symposium on Glaucoma: Transactions of the New Orleans Academy of Ophthalmology . St Louis, CV Mosby Co, 1975, pp 151-189. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Optic Disc in Glaucoma: Topography and Extent of Fluorescein Filling Defects

Download PDF
5 pages

Loading next page...
 
/lp/american-medical-association/optic-disc-in-glaucoma-topography-and-extent-of-fluorescein-filling-VYGeha83yX

References (12)

Publisher
American Medical Association
Copyright
Copyright © 1977 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1977.04450110069003
Publisher site
See Article on Publisher Site

Abstract

Abstract • The topography and extent of localized areas of hypofluorescence or absolute filling defects of the optic discs of glaucomatous patients correlated positively with the loss of visual field. Filling defects tended to cluster at the inferior and superior poles of the optic disc and were closer to the disc margin than to the center. The location of the defects corresponded with the expected site of visual field loss. There was a positive correlation between the percent area of the filling defects and the degree of visual field loss. These observations support the concept that fluorescein filling defects of the optic disc in glaucoma represent areas of ischemia that are highly correlated with loss of visual field. (Arch Ophthalmol 95:1975-1979, 1977) References 1. Hayreh SS, Walker WM: Fluorescent fundus photography in glaucoma . Am J Ophthalmol 63:982-989, 1967. 2. Hayreh SS: Blood supply of the optic nerve head and its role in optic atrophy, glaucoma, and oedema of the optic disc . Br J Ophthalmol 53:721-748, 1969.Crossref 3. Oosterhuis JA, Gortzak-Moorstein M: Fluorescein angiography of the optic disc in galucoma . Ophthalmologica 160:331-353, 1970.Crossref 4. Raitta C, Sarmela T: Fluorescein angiography of the optic disc and the peripapillary area in chronic glaucoma . Acta Ophthalmol 48:303-308, 1970.Crossref 5. Batrachenko IP: Fluorescein angioretinography in primary glaucoma . Vestn Oftalmol 83( (3) ):22-26, 1970. 6. Karel I, Kraus H, Peleska M: Contribution to the fluoroangiographic findings in open-angle glaucoma . CS Oftalmol 31:40-46, 1975. 7. Begg IS, Drance SM, Goldman H: Fluorescein angiography in the evaluation of focal circulatory ischaemia of the optic nerve head in relation to the arcuate scotoma in glaucoma . Can J Ophthalmol 7:68-74, 1972. 8. Spaeth GL: Fluorescein angiography: Its contribution towards understanding the mechanisms of visual loss in glaucoma . Trans Am Ophthalmol Soc 73:491-553, 1975. 9. Schwartz B: New techniques for the examination of the optic disc and their clinical application . Trans Am Acad Ophthalmol Otolaryngol 81:OP 227-237, 1976. 10. Siegel S: Non Parametric Statistics for the Behavioral Services . New York, McGraw-Hill Book Co Inc, 1956. 11. Traquair HM: The nerve-fiber bundle defect . Trans Ophthalmol Soc UK 64:3-23, 1944. 12. Lynn JR: Correlation of pathogenesis, anatomy and patterns of visual field loss in glaucoma in Symposium on Glaucoma: Transactions of the New Orleans Academy of Ophthalmology . St Louis, CV Mosby Co, 1975, pp 151-189.

Journal

Archives of Ophthalmology – American Medical Association

Published: Nov 1, 1977

There are no references for this article.