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Echothiophate, Pilocarpine, and Open-Angle Glaucoma

Echothiophate, Pilocarpine, and Open-Angle Glaucoma Abstract In 44 patients with open-angle glaucoma under treatment with echothiophate, tensions were compared with and without simultaneous treatment with pilocarpine. In most cases, echothiophate is as effective alone as in combination with pilocarpine. This finding is described with reference to current views on the nature of the cholinergic receptor. References 1. Pratt-Johnson JA, Drance SM, Innes R: Comparison between pilocarpine and echothiophate for chronic simple glaucoma . Arch Ophthalmol 72:485-488, 1964.Crossref 2. Fisher R, Smith R, Wheeler C: Comparison between the tonographic effects of pilocarpine and echothiophate in glaucoma simplex . Br J Ophthalmol 49:369-373, 1965.Crossref 3. Becker B, Shaffer R: Diagnosis and Therapy of Glaucoma , ed 2. St. Louis, CV Mosby Co Publishers, 1965. 4. Changeux JP, Kasai M, Lee CY: Use of a snake venom to characterize the cholinergic receptor protein . Proc Natl Acad Sci USA 67:1241-1247, 1970.Crossref 5. Miledi R, Molinoff R, Potter LT: Isolation of the cholinergic receptor protein of Torpedo electric tissue . Nature 229:554-557, 1971.Crossref 6. Eldefrawi ME, Eldefrawi AT: Characterization and purification of the acetylcholine receptor from Torpedo electroplax . Proc Natl Acad Sci USA 69:1776-1780, 1972.Crossref 7. Eldefrawi ME, Eldefrawi AT, O'Brien RD: Binding sites for cholinergic ligands in a particulate fraction of Electrophorus electroplax . Proc Natl Acad Sci USA 68:1047-1050, 1971.Crossref 8. Denburg JL, Eldefrawi ME, O'Brien RD: Macromolecules from lobster membranes that bind cholinergic ligands and local anesthetics . Proc Natl Acad Sci USA 69:177-181, 1972.Crossref 9. Miledi R, Potter LT: Acetylcholine receptors in muscle fibers . Nature 233:599-603, 1971.Crossref 10. O'Brien RD, Gilmour LP, Eldefrawi ME: A muscarone-binding material in electroplax and its relation to the acetylcholine receptor: XI. Dialysis assay . Proc Natl Acad Sci USA 65:438-445, 1970.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Echothiophate, Pilocarpine, and Open-Angle Glaucoma

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References (13)

Publisher
American Medical Association
Copyright
Copyright © 1973 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1973.01000040192005
Publisher site
See Article on Publisher Site

Abstract

Abstract In 44 patients with open-angle glaucoma under treatment with echothiophate, tensions were compared with and without simultaneous treatment with pilocarpine. In most cases, echothiophate is as effective alone as in combination with pilocarpine. This finding is described with reference to current views on the nature of the cholinergic receptor. References 1. Pratt-Johnson JA, Drance SM, Innes R: Comparison between pilocarpine and echothiophate for chronic simple glaucoma . Arch Ophthalmol 72:485-488, 1964.Crossref 2. Fisher R, Smith R, Wheeler C: Comparison between the tonographic effects of pilocarpine and echothiophate in glaucoma simplex . Br J Ophthalmol 49:369-373, 1965.Crossref 3. Becker B, Shaffer R: Diagnosis and Therapy of Glaucoma , ed 2. St. Louis, CV Mosby Co Publishers, 1965. 4. Changeux JP, Kasai M, Lee CY: Use of a snake venom to characterize the cholinergic receptor protein . Proc Natl Acad Sci USA 67:1241-1247, 1970.Crossref 5. Miledi R, Molinoff R, Potter LT: Isolation of the cholinergic receptor protein of Torpedo electric tissue . Nature 229:554-557, 1971.Crossref 6. Eldefrawi ME, Eldefrawi AT: Characterization and purification of the acetylcholine receptor from Torpedo electroplax . Proc Natl Acad Sci USA 69:1776-1780, 1972.Crossref 7. Eldefrawi ME, Eldefrawi AT, O'Brien RD: Binding sites for cholinergic ligands in a particulate fraction of Electrophorus electroplax . Proc Natl Acad Sci USA 68:1047-1050, 1971.Crossref 8. Denburg JL, Eldefrawi ME, O'Brien RD: Macromolecules from lobster membranes that bind cholinergic ligands and local anesthetics . Proc Natl Acad Sci USA 69:177-181, 1972.Crossref 9. Miledi R, Potter LT: Acetylcholine receptors in muscle fibers . Nature 233:599-603, 1971.Crossref 10. O'Brien RD, Gilmour LP, Eldefrawi ME: A muscarone-binding material in electroplax and its relation to the acetylcholine receptor: XI. Dialysis assay . Proc Natl Acad Sci USA 65:438-445, 1970.Crossref

Journal

Archives of Ophthalmology – American Medical Association

Published: Mar 1, 1973

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