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Anomalies of Iris and Anterior-Chamber Angle: Occurrence in a Child With Multiple Congenital Anomalies

Anomalies of Iris and Anterior-Chamber Angle: Occurrence in a Child With Multiple Congenital... Abstract THE PURPOSE of this paper is to report the peculiar ocular histopathologic changes of an anomalous cleavage of the anterior chamber angle, choristomatous cornea-like tissue on the anterior iris surface, and a membrane in the chamber angle in an infant with multiple congenital anomalies. Report of a Case This 2-month-old white female infant died at St. Christopher's Hospital for Children on Jan 9, 1967 (autopsy: A-3-67; Wilmer Eye Pathology 29294). The infant's body was grossly malformed, exhibiting generalized asymmetry. The body weighed 2,124 gm (4 lb 10½ oz). The head was markedly flattened on the right side; the fontanel was located above the midportion of the left eyebrow rather than in the midline. The right eye bulged forward considerably. The pupil of the right eye was irregular, and the iris near the pupil had a rim of whitish tissue around it. The left eye was considered normal. The mandible References 1. Allen L, Burian HM, Braley AE: A new concept of the development of the anterior chamber angle . Arch Ophthal 53:783-798, 1955.Crossref 2. Maumenee AE: The pathogenesis of congenital glaucoma: A new theory . Trans Amer Ophthal Soc 56:507-570, 1958. 3. Collins ET: The anatomy and pathology of the eye . Lancet 1:435-444, 1900. 4. Luxenberg MN: Hyperplasia of the anterior layer of the iris stroma . Brit J Ophthal 49:516-520, 1965.Crossref 5. Wolter JR, Fechner PU: Glass membranes on the anterior iris surface . Amer J Ophthal 53:235-243, 1962. 6. Barkan O: Pathogenesis of congenital glaucoma . Amer J Ophthal 40:1-11, 1955. 7. Worst JGF: The cause and treatment of congenital glaucoma . Trans Amer Acad Ophthal Otolaryng 68:766-788, 1964. 8. Maumenee AE: Further observations on the pathogenesis of congenital glaucoma . Trans Amer Ophthal Soc 60:140-162, 1962. 9. Reese AB, Ellsworth RM: The anterior chamber cleavage syndrome . Arch Ophthal 75:307-318, 1966.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Anomalies of Iris and Anterior-Chamber Angle: Occurrence in a Child With Multiple Congenital Anomalies

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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1971 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1971.01000010289009
Publisher site
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Abstract

Abstract THE PURPOSE of this paper is to report the peculiar ocular histopathologic changes of an anomalous cleavage of the anterior chamber angle, choristomatous cornea-like tissue on the anterior iris surface, and a membrane in the chamber angle in an infant with multiple congenital anomalies. Report of a Case This 2-month-old white female infant died at St. Christopher's Hospital for Children on Jan 9, 1967 (autopsy: A-3-67; Wilmer Eye Pathology 29294). The infant's body was grossly malformed, exhibiting generalized asymmetry. The body weighed 2,124 gm (4 lb 10½ oz). The head was markedly flattened on the right side; the fontanel was located above the midportion of the left eyebrow rather than in the midline. The right eye bulged forward considerably. The pupil of the right eye was irregular, and the iris near the pupil had a rim of whitish tissue around it. The left eye was considered normal. The mandible References 1. Allen L, Burian HM, Braley AE: A new concept of the development of the anterior chamber angle . Arch Ophthal 53:783-798, 1955.Crossref 2. Maumenee AE: The pathogenesis of congenital glaucoma: A new theory . Trans Amer Ophthal Soc 56:507-570, 1958. 3. Collins ET: The anatomy and pathology of the eye . Lancet 1:435-444, 1900. 4. Luxenberg MN: Hyperplasia of the anterior layer of the iris stroma . Brit J Ophthal 49:516-520, 1965.Crossref 5. Wolter JR, Fechner PU: Glass membranes on the anterior iris surface . Amer J Ophthal 53:235-243, 1962. 6. Barkan O: Pathogenesis of congenital glaucoma . Amer J Ophthal 40:1-11, 1955. 7. Worst JGF: The cause and treatment of congenital glaucoma . Trans Amer Acad Ophthal Otolaryng 68:766-788, 1964. 8. Maumenee AE: Further observations on the pathogenesis of congenital glaucoma . Trans Amer Ophthal Soc 60:140-162, 1962. 9. Reese AB, Ellsworth RM: The anterior chamber cleavage syndrome . Arch Ophthal 75:307-318, 1966.Crossref

Journal

Archives of Ophthalmology – American Medical Association

Published: Sep 1, 1971

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