Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Ultrastructure of the Optic Nerve Head

Ultrastructure of the Optic Nerve Head Abstract Astrocyte cell bodies and processes form a continuous limiting membrane of varying thickness over the optic disk surface. The surface contour is irregular in places. Basement membrane separates glia from vitreous. The layer of glia is continuous with the internal limiting membrane of the retina, which is similar but has a thicker basement membrane and is formed by foot plates of Müller cells (a kind of astrocyte) instead of spider-cell astrocytes. As throughout the central nervous system (CNS), the endothelium of the central retinal vessels is nonfenestrated and held together by tight junctions. The artery has a media of smooth muscle, but the media of the vein is discontinuous. The central retinal artery loses its internal elastic membrane as it enters the eye, where tissue pressure is higher. The vascular adventitia is enclosed by astroglia. References 1. Anderson, D.R., and Hoyt, W.F.: Ultrastructure of Intraorbital Portion of Human and Monkey Optic Nerve , Arch Ophthal 82:506-530 ( (Oct) ) 1969.Crossref 2. Anderson, D.R.: Ultrastructure of Meningeal Sheaths: Normal Human and Monkey Optic Nerves , Arch Ophthal 82:659-674 ( (Nov) ) 1969.Crossref 3. Anderson, D.R.: Ultrastructure of Human and Monkey Lamina Cribrosa and Optic Nerve Head , Arch Ophthal 82:800-814 ( (Dec) ) 1969.Crossref 4. Anderson, D.R.; Hoyt, W.F.; and Hogan, M.J.: The Fine Structure of the Astroglia in the Human Optic Nerve and Optic Nerve Head , Trans Amer Ophthal Soc 65:275-305, 1967. 5. Elschnig, A.: Der normale Sehnerveneintritt des menschlichen Auges , Denkschriften mathematischnaturwissenschaftliche Classe der Kaiserlichen Akademie Wissenschaften 70:219-303, 1901. 6. Hogan, M.J., and Feeney, L.: The Ultrastructure of the Retinal Blood Vessels: I. The Large Vessels , J Ultrastruct Res 9:10-28 ( (Aug) ) 1963.Crossref 7. Ikui, J.; Tominaga, Y.; and Mimura, K.: The Fine Structure of the Central Retinal Artery and Vein in the Optic Nerve of the Human Eye and the Pathological Changes Found Occurring Therein in Hypertension and Arteriosclerosis , Acta Soc Ophthal Jap 689:899-911, 1964. 8. Hogan, M.J., and Feeney, L.: The Ultrastructure of the Retinal Vessels: III. Vascular-Glial Relationships , J Ultrastruct Res 9:47-64 ( (Aug) ) 1963.Crossref 9. Lasansky, A., and Wald, F.: The Extracellular Space in the Toad Retina as Defined by the Distribution of Ferrocyanide , J Cell Biol 15:463-479 ( (Dec) ) 1962.Crossref 10. Gärtner, J.: Die Bedeutung des perivasculären Raumes der Zentralgefässe für den vitreopapillären Stofftransport beim normalen Mäuseauge und beim menschlichen Auge unter pathologischen Bedingungen , Graefe Arch Klin Exp Ophthal 175:13-27, 1968.Crossref 11. Kuffler, S.W., and Nicholls, J.G.: The Physiology of Neuroglial Cells , Ergebn Physiol 57:1-90, 1966.Crossref 12. Lampert, P.W.; Vogel, M.H.; and Zimmerman, L.E.: Pathology of the Optic Nerve in Experimental Acute Glaucoma: Electron Microscopic Studies , Invest Ophthal 7:199-213 ( (April) ) 1968. 13. Gärtner, J.: Elektronenmikroskopische Beobachtungen an der Papille des Rattenauges und beim Papillenödem des Menschen , Ophthalmologica (Basel) 153:367-384, 1967.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Ultrastructure of the Optic Nerve Head

Anderson, Douglas R.
Archives of Ophthalmology , Volume 83 (1) – Jan 1, 1970
Download PDF
11 pages

Loading next page...
 
/lp/american-medical-association/ultrastructure-of-the-optic-nerve-head-7afL6IyelA

References (13)

Publisher
American Medical Association
Copyright
Copyright © 1970 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1970.00990030065013
Publisher site
See Article on Publisher Site

Abstract

Abstract Astrocyte cell bodies and processes form a continuous limiting membrane of varying thickness over the optic disk surface. The surface contour is irregular in places. Basement membrane separates glia from vitreous. The layer of glia is continuous with the internal limiting membrane of the retina, which is similar but has a thicker basement membrane and is formed by foot plates of Müller cells (a kind of astrocyte) instead of spider-cell astrocytes. As throughout the central nervous system (CNS), the endothelium of the central retinal vessels is nonfenestrated and held together by tight junctions. The artery has a media of smooth muscle, but the media of the vein is discontinuous. The central retinal artery loses its internal elastic membrane as it enters the eye, where tissue pressure is higher. The vascular adventitia is enclosed by astroglia. References 1. Anderson, D.R., and Hoyt, W.F.: Ultrastructure of Intraorbital Portion of Human and Monkey Optic Nerve , Arch Ophthal 82:506-530 ( (Oct) ) 1969.Crossref 2. Anderson, D.R.: Ultrastructure of Meningeal Sheaths: Normal Human and Monkey Optic Nerves , Arch Ophthal 82:659-674 ( (Nov) ) 1969.Crossref 3. Anderson, D.R.: Ultrastructure of Human and Monkey Lamina Cribrosa and Optic Nerve Head , Arch Ophthal 82:800-814 ( (Dec) ) 1969.Crossref 4. Anderson, D.R.; Hoyt, W.F.; and Hogan, M.J.: The Fine Structure of the Astroglia in the Human Optic Nerve and Optic Nerve Head , Trans Amer Ophthal Soc 65:275-305, 1967. 5. Elschnig, A.: Der normale Sehnerveneintritt des menschlichen Auges , Denkschriften mathematischnaturwissenschaftliche Classe der Kaiserlichen Akademie Wissenschaften 70:219-303, 1901. 6. Hogan, M.J., and Feeney, L.: The Ultrastructure of the Retinal Blood Vessels: I. The Large Vessels , J Ultrastruct Res 9:10-28 ( (Aug) ) 1963.Crossref 7. Ikui, J.; Tominaga, Y.; and Mimura, K.: The Fine Structure of the Central Retinal Artery and Vein in the Optic Nerve of the Human Eye and the Pathological Changes Found Occurring Therein in Hypertension and Arteriosclerosis , Acta Soc Ophthal Jap 689:899-911, 1964. 8. Hogan, M.J., and Feeney, L.: The Ultrastructure of the Retinal Vessels: III. Vascular-Glial Relationships , J Ultrastruct Res 9:47-64 ( (Aug) ) 1963.Crossref 9. Lasansky, A., and Wald, F.: The Extracellular Space in the Toad Retina as Defined by the Distribution of Ferrocyanide , J Cell Biol 15:463-479 ( (Dec) ) 1962.Crossref 10. Gärtner, J.: Die Bedeutung des perivasculären Raumes der Zentralgefässe für den vitreopapillären Stofftransport beim normalen Mäuseauge und beim menschlichen Auge unter pathologischen Bedingungen , Graefe Arch Klin Exp Ophthal 175:13-27, 1968.Crossref 11. Kuffler, S.W., and Nicholls, J.G.: The Physiology of Neuroglial Cells , Ergebn Physiol 57:1-90, 1966.Crossref 12. Lampert, P.W.; Vogel, M.H.; and Zimmerman, L.E.: Pathology of the Optic Nerve in Experimental Acute Glaucoma: Electron Microscopic Studies , Invest Ophthal 7:199-213 ( (April) ) 1968. 13. Gärtner, J.: Elektronenmikroskopische Beobachtungen an der Papille des Rattenauges und beim Papillenödem des Menschen , Ophthalmologica (Basel) 153:367-384, 1967.Crossref

Journal

Archives of Ophthalmology – American Medical Association

Published: Jan 1, 1970

There are no references for this article.