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Spring-Driven Apparatus for Needle Placement into the Eyes of Rabbits

Spring-Driven Apparatus for Needle Placement into the Eyes of Rabbits Abstract An automatic injection apparatus mounted on a micromanipulator is described for mechanical insertion of needle cannula into the anterior chamber of the rabbit eye. The apparatus minimizes the trauma of entering the anterior chamber and reduces the variability in intraocular pressure. This procedure is useful for injection of compounds into the anterior chamber or for evacuation and refilling of the anterior chamber as desired in some test procedures. References 1. Prince, J.: The Rabbit in Eye Research , Springfield, Ill: Charles C Thomas, 1965, p 338. 2. Davson, H.: The Eye , New York: Academic Press, 1962, vol 1, p 167. 3. Perkins, E.S.: Influence of the Fifth Cranial Nerve on the Intraocular Pressure of the Rabbit Eye , Brit J Ophthal 41:257-300, 1957.Crossref 4. Sears, M.A.: Miosis and Intraocular Pressure Changes During Manometry , Arch Ophthal 63:707-714, 1960.Crossref 5. Kazdan, J.J., et al: A Technique for Experimental Angle Block in Rabbits Avoiding the Paracentesis Reflex , Amer J Ophthal 59:463-465, 1965. 6. Stone, H.H., and Prijot, E.L.: The Effect of a Barbiturate and Paraldehyde on Aqueous Humor Dynamics in Rabbits , Arch Ophthal 54:834-840, 1955.Crossref 7. Lorenzetti, O.J., and Sancilio, L.F.: Procedure for Evaluating Drug Effects on Increased Intraocular Pressure , Fed Proc 25 (pt 1) :502, 1966. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Spring-Driven Apparatus for Needle Placement into the Eyes of Rabbits

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References (9)

Publisher
American Medical Association
Copyright
Copyright © 1967 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1967.00980020548020
Publisher site
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Abstract

Abstract An automatic injection apparatus mounted on a micromanipulator is described for mechanical insertion of needle cannula into the anterior chamber of the rabbit eye. The apparatus minimizes the trauma of entering the anterior chamber and reduces the variability in intraocular pressure. This procedure is useful for injection of compounds into the anterior chamber or for evacuation and refilling of the anterior chamber as desired in some test procedures. References 1. Prince, J.: The Rabbit in Eye Research , Springfield, Ill: Charles C Thomas, 1965, p 338. 2. Davson, H.: The Eye , New York: Academic Press, 1962, vol 1, p 167. 3. Perkins, E.S.: Influence of the Fifth Cranial Nerve on the Intraocular Pressure of the Rabbit Eye , Brit J Ophthal 41:257-300, 1957.Crossref 4. Sears, M.A.: Miosis and Intraocular Pressure Changes During Manometry , Arch Ophthal 63:707-714, 1960.Crossref 5. Kazdan, J.J., et al: A Technique for Experimental Angle Block in Rabbits Avoiding the Paracentesis Reflex , Amer J Ophthal 59:463-465, 1965. 6. Stone, H.H., and Prijot, E.L.: The Effect of a Barbiturate and Paraldehyde on Aqueous Humor Dynamics in Rabbits , Arch Ophthal 54:834-840, 1955.Crossref 7. Lorenzetti, O.J., and Sancilio, L.F.: Procedure for Evaluating Drug Effects on Increased Intraocular Pressure , Fed Proc 25 (pt 1) :502, 1966.

Journal

Archives of Ophthalmology – American Medical Association

Published: Apr 1, 1967

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