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Y. Nakaizumi, M. Hogan, L. Feeney (1964)
THE ULTRASTRUCTURE OF BRUCH'S MEMBRANE. 3. THE MACULAR AREA OF THE HUMAN EYE.Archives of ophthalmology, 72
F.H. Verhoeff (1937)
Pathogenesis of Disciform Degeneration of the MaculaArch Ophthal, 18
Y. Nakaizumi (1964)
THE ULTRASTRUCTURE OF BRUCH'S MEMBRANE. I. HUMAN, MONKEY, RABBIT, GUINEA PIG, AND RAT EYES.Archives of ophthalmology, 72
A. Elschnig (1919)
Tumorahniche Gewebswucheryng in der Macula LuteaKlin Mbl Augenheilk, 62
P. Junius (1926)
Die scheibenformige Entartung der Netzhautmitte
M.L. Feeney (1961)
The Structure of the Eye
G. Martin, Elliott Schiffmann, H. Bladen, M. Nylen (1963)
CHEMICAL AND MORPHOLOGICAL STUDIES ON THE IN VITRO CALCIFICATION OF AORTAThe Journal of Cell Biology, 16
Speakman Js (1961)
The Structure of the Trabecular Meshwork in Relation to the Pathogenesis of Open Angle Glaucoma.Canadian Medical Association journal, 84 19
M.J. Hogan (1961)
Ultrastructure of the Choroid: Its Role in the Pathogenesis of Choroidal DiseasesTrans Pacif Coast Otoophthal Soc, 42
K. Wybar (1954)
Vascular Anatomy of the Choroid in Relation to Selective Localization of Ocular Disease *British Journal of Ophthalmology, 38
A.L. Kornzweig , M. Feldstein, J. and Schneider (1959)
The Pathogenesis of Senile Macular DegeneraationAmer J Ophthal, 48
E. Friedman , T. Smith, T. and Kuwabara (1963)
Choroidal Vascular Patterns and DrusenArch Ophthal, 69
E. Friedman (1965)
Pathogenesis: Senile Changes of the Choriocapillaris of the Posterior PoleTrans Amer Acad Ophthal Otolaryng, 69
W. Johnson, J. Graham, E. Helwig (1964)
HISTOCHEMISTRY OF THE ACID MUCOPOLYSACCHARIDES IN CUTANEOUS CALCIFICATION.The Journal of investigative dermatology, 42
B. Klien (1950)
The Heredodegeneration of the Macula Lutea*: Diagnostic and Differential Diagnostic Considerations and A Histopathologic ReportAmerican Journal of Ophthalmology, 33
Kornzweig Al (1965)
MACULAR DISEASES: PATHOGENESIS. DISEASES OF THE MACULA IN THE AGED.Transactions - American Academy of Ophthalmology and Otolaryngology, 69
F. Verhoeff, H. Grossman (1937)
The Pathogenesis of Disciform Degeneration of the Macula.Transactions of the American Ophthalmological Society, 35
B Klien (1958)
Diseases of the MaculaArch Ophthal, 60
B. Klien (1989)
Macular Lesions of Vascular Origin: I. Organic Vascular Lesions Leading to Damage of the Macula LuteaAmer J Ophthal, 34
L. Garron (1963)
The Ultrastructure of the Retinal Pigment Epithelium with Observations on the Choriocapillaris and Bruch's Membrane.Transactions of the American Ophthalmological Society, 61
A.L. Kornzweig (1962)
Pathogenesis: Diseases of the Macula in the AgedTrans Amer Acad Ophthal Otolaryng, 69
D.G. Cogan (1963)
Development and Senescence of the Human Retinal Vasculature (Doyne Memorial Lecture 1963)Trans Ophthal Soc UK, 83
F.H. Verhoeff (1926)
Basophilic Staining of Bruch's MembraneArch Ophthal, 55
B. Klien (1964)
SOME ASPECTS OF CLASSIFICATION AND DIFFERENTIAL DIAGNOSIS OF SENILE MACULAR DEGENERATION.American journal of ophthalmology, 58
B. Klien (1953)
Macular lesions of vascular origin. II. Functional vascular conditions leading to damage of the macula lutea.American journal of ophthalmology, 36 1
Abstract Electron microscopy of 15 human eyes from patients aged 2 to 82, was done to study aging changes in Bruch's membrane and their relation to senile macular degeneration. The membrane increased twofold to threefold in thickness from childhood to adult life. The basal laminas did not change. With increasing age the membrane accumulated 640 A and 1,100 A type collagen. Clumps were found near the choriocapillaris, often indenting its wall, and in the intercapillary zones. With increasing age vesicular structures accumulated in all zones, mainly internally. Tube-like structures, possibly altered collagen also appeared in the outer collagen zone. Because of these new accumulations the elastic layer became less distinct. Crystal formation was seen on collagen and elastic fibers. References 1. Klien, B.: The Heredodegenerations of the Macula Lutea: Diagnostic and Differential Diagnostic Considerations and a Histopathologic Report , Amer J Ophthal 33:371-379 ( (March) ) 1950. 2. Verhoeff, F.H., and Grossman, H.P.: Pathogenesis of Disciform Degeneration of the Macula , Arch Ophthal 18:561-585 ( (Oct) ) 1937.Crossref 3. Junius, P., and Kuhnt, H.: Die scheibenformige Entartung der Netzhautmitte , Berlin: S. Karger, 1926. 4. Elschnig, A.: Tumorahniche Gewebswucheryng in der Macula Lutea , Klin Mbl Augenheilk 62:145-154, 1919. 5. Klien, B.: Macular Lesions of Vascular Origin: I. Organic Vascular Lesions Leading to Damage of the Macula Lutea , Amer J Ophthal 34:1279, 1989, 1951. 6. Klien, B.: Macular Lesions of Vascular Origin: II. Functional Vascular Conditions Leading to Damage of the Macula Lutea , Amer J. Ophthal 36:1-13, 1953. 7. Klien, B: Diseases of the Macula , Arch Ophthal 60:175-186 ( (Aug) ) 1958.Crossref 8. Wybar, K.C.: Vascular Anatomy of the Choroid in Relation to Selective Localization of Ocular Disease , Brit J Ophthal 38:513-527, 1952.Crossref 9. Friedman, E., and Smith, T.R.: Pathogenesis: Senile Changes of the Choriocapillaris of the Posterior Pole; Symposium: Macular Diseases , Trans Amer Acad Ophthal Otolaryng 69:652-661 ( (July-Aug) ) 1965. 10. Kline, B.A.: Some Aspects of Classification and Differential Diagnosis of Senile Macular Degeneration , Amer J Ophthal 58:927-939 ( (Dec) ) 1964. 11. Friedman, E.; Smith, T.; and Kuwabara, T.: Choroidal Vascular Patterns and Drusen , Arch Ophthal 69:220-230, 1963.Crossref 12. Hogan, M.J.: Ultrastructure of the Choroid: Its Role in the Pathogenesis of Choroidal Diseases , Trans Pacif Coast Otoophthal Soc 42:61-87, 1961. 13. Verhoeff, F.H., and Sisson, R.J.: Basophilic Staining of Bruch's Membrane , Arch Ophthal 55:125-127, 1926. 14. Kornzweig, A.L.; Feldstein, M.; and Schneider, J.: The Pathogenesis of Senile Macular Degeneraation , Amer J Ophthal 48( (pt 2) ):22-28 (July) 1959. 15. Kornzweig, A.L.: Pathogenesis: Diseases of the Macula in the Aged; Symposium; Macular Diseases , Trans Amer Acad Ophthal Otolaryng 69:668-682 ( (July-Aug) ) 1962. 16. Cogan, D.G.: Development and Senescence of the Human Retinal Vasculature (Doyne Memorial Lecture 1963) , Trans Ophthal Soc UK 83:465-489, 1963. 17. Garron, L.K.: The Ultrastructure of the Retinal Pigment Epithelium With Observations on the Choriocapillaris and Bruch's Membrane , Trans Amer Ophthal Soc 61:545-588, 1963. 18. Nakaizumi, Y.: The Ultrastructure of Bruch's Membrane: I. Human, Monkey, Rabbit, Guinea Pig, and Rat Eyes , Arch Ophthal 72:380-387 ( (Sept) ) 1964.Crossref 19. Nakaizumi, U.; Hogan, M.J.; and Feeney, L.: The Ultrastructure of Bruch's Membrane: III. The Macular Area of the Human Eye , Arch Ophthal 72:395-400 ( (Sept) ) 1964.Crossref 20. Speakman, J.S.: The Structure of the Trabecular Meshwork in Relation to the Pathogenesis of Open Angle Glaucoma , Canad Med Assoc J 84:1066-1074 ( (May 12) ) 1961. 21. Feeney, M.L., and Garron, K.L.: " Descemet's Membrane in the Human Peripheral Cornea: A Study by Light and Electron Microscopy ," in Smelser, G.K. (ed.): The Structure of the Eye , New York and London: Academic Press, Inc, 1961, pp 367-377. 22. Johnson, W.C.; Graham, J.H.; and Helwig, E.B.: Histochemistry of the Acid Mucopolysaccharides in Cutaneous Calcification , J Invest Derm 42:215-224 ( (Feb) ) 1964. 23. Martin, G.R., et al: Chemical and Morphological Studies on the In Vitro Calcification of Aorta , J Cell Biol 16:243-252, 1963.Crossref
Archives of Ophthalmology – American Medical Association
Published: Mar 1, 1967
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