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Corticosteroids, Glaucoma, and Time

Corticosteroids, Glaucoma, and Time Abstract We are living in a time of amazingly effective pharmacologic agents. Though the usefulness of medications like the corticosteroids is unquestioned, the undesirable side effects of such active chemicals has come as an unpleasant shock to doctor and patient alike. Untold glaucomatous damage to optic nerves has occurred during the period when physicians were furnished with steroid-antibiotic combinations designed to cure ocular irritation without need for etiologic diagnosis. It is unusual for such an undersirable side-effect to be found useful in scientific investigation. By their investigation of the intraocular pressure response to the chronic use of the corticosteroids, Bernard Becker and his co-workers in St. Louis have added a whole new chapter to our understanding of glaucoma. These statistics have led to the hypothesis of the recessive inheritance of open-angle glaucoma ("Glaucoma and Corticosteroid Provocative Testing," page 621 of this issue"). In essence, the hypothesis states that nearly 30% of References 1. Grant No. CD-00014-07 USPHS. Johns Hopkins University, University of California, Washington University, State University of Iowa, and New York University. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Corticosteroids, Glaucoma, and Time

Archives of Ophthalmology , Volume 74 (5) – Nov 1, 1965

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Publisher
American Medical Association
Copyright
Copyright © 1965 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1965.00970040596002
Publisher site
See Article on Publisher Site

Abstract

Abstract We are living in a time of amazingly effective pharmacologic agents. Though the usefulness of medications like the corticosteroids is unquestioned, the undesirable side effects of such active chemicals has come as an unpleasant shock to doctor and patient alike. Untold glaucomatous damage to optic nerves has occurred during the period when physicians were furnished with steroid-antibiotic combinations designed to cure ocular irritation without need for etiologic diagnosis. It is unusual for such an undersirable side-effect to be found useful in scientific investigation. By their investigation of the intraocular pressure response to the chronic use of the corticosteroids, Bernard Becker and his co-workers in St. Louis have added a whole new chapter to our understanding of glaucoma. These statistics have led to the hypothesis of the recessive inheritance of open-angle glaucoma ("Glaucoma and Corticosteroid Provocative Testing," page 621 of this issue"). In essence, the hypothesis states that nearly 30% of References 1. Grant No. CD-00014-07 USPHS. Johns Hopkins University, University of California, Washington University, State University of Iowa, and New York University.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Nov 1, 1965

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