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Management of Juvenile Xanthogranuloma of the Iris

Management of Juvenile Xanthogranuloma of the Iris Abstract Spontaneous nontraumatic hyphema occurring in an infant is unusual. Most frequently it is the result of a disease entity recognized relatively recently, juvenile xanthogranuloma (nevoxanthoendothelioma) of the iris.1-5 Generally a diffuse or localized iris lesion is visible clinically, and severe glaucoma results if the disease is not recognized and treated. Characteristic skin lesions are present in some cases. Juvenile xanthogranuloma of the iris has been treated successfully with radiation,1,3 combined radiation and steroid therapy,2 and excisional biopsy.5 In this report, two cases illustrating proper and improper management of juvenile xanthogranuloma of the iris are presented, and an outline for therapy is discussed. Case 1. —A 9-month-old Caucasian girl was well until about 3½ months of age, when her mother noted congestion of the right eye and a lesion on the iris. Examination under general anesthesia revealed a normal left eye. The right eye contained a small References 1. Hedges, C. C., Jr.: Nevoxanthoendothelioma of the Eye Treated with Superficial X-Ray Therapy , Amer J Ophthal 47:683, 1959. 2. Maumenee, A. E., and Longfellow, D. W.: Treatment of Intraocular Nevoxanthoendothelioma (Juvenile Xanthogranuloma) , Amer J Ophthal 49:1, 1960. 3. Cleasby, G. W.: Nevoxanthoendothelioma (Juvenile Xanthogranuloma of the Iris) , Arch Ophthal (Chicago) 66:26-28, 1961.Crossref 4. Sanders, T. E.: Intraocular Juvenile Xantho-Granuloma (Nevoxantho-Endothelioma) , Amer J Ophthal 53:455, 1962. 5. Howard, G. M.: Spontaneous Hyphema in Infancy and Childhood , Arch Ophthal (Chicago) 68:615-620, 1962.Crossref 6. Goldmann, H.: Cortisone Glaucoma , Arch Ophthal (Chicago) 68:621-626, 1962.Crossref 7. Becker, B., and Mills, D. W.: Corticosteroids and Intraocular Pressure , Arch Ophthal (Chicago) 70:500-507, 1963.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Management of Juvenile Xanthogranuloma of the Iris

Archives of Ophthalmology , Volume 71 (3) – Mar 1, 1964

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References (8)

Publisher
American Medical Association
Copyright
Copyright © 1964 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1964.00970010360009
Publisher site
See Article on Publisher Site

Abstract

Abstract Spontaneous nontraumatic hyphema occurring in an infant is unusual. Most frequently it is the result of a disease entity recognized relatively recently, juvenile xanthogranuloma (nevoxanthoendothelioma) of the iris.1-5 Generally a diffuse or localized iris lesion is visible clinically, and severe glaucoma results if the disease is not recognized and treated. Characteristic skin lesions are present in some cases. Juvenile xanthogranuloma of the iris has been treated successfully with radiation,1,3 combined radiation and steroid therapy,2 and excisional biopsy.5 In this report, two cases illustrating proper and improper management of juvenile xanthogranuloma of the iris are presented, and an outline for therapy is discussed. Case 1. —A 9-month-old Caucasian girl was well until about 3½ months of age, when her mother noted congestion of the right eye and a lesion on the iris. Examination under general anesthesia revealed a normal left eye. The right eye contained a small References 1. Hedges, C. C., Jr.: Nevoxanthoendothelioma of the Eye Treated with Superficial X-Ray Therapy , Amer J Ophthal 47:683, 1959. 2. Maumenee, A. E., and Longfellow, D. W.: Treatment of Intraocular Nevoxanthoendothelioma (Juvenile Xanthogranuloma) , Amer J Ophthal 49:1, 1960. 3. Cleasby, G. W.: Nevoxanthoendothelioma (Juvenile Xanthogranuloma of the Iris) , Arch Ophthal (Chicago) 66:26-28, 1961.Crossref 4. Sanders, T. E.: Intraocular Juvenile Xantho-Granuloma (Nevoxantho-Endothelioma) , Amer J Ophthal 53:455, 1962. 5. Howard, G. M.: Spontaneous Hyphema in Infancy and Childhood , Arch Ophthal (Chicago) 68:615-620, 1962.Crossref 6. Goldmann, H.: Cortisone Glaucoma , Arch Ophthal (Chicago) 68:621-626, 1962.Crossref 7. Becker, B., and Mills, D. W.: Corticosteroids and Intraocular Pressure , Arch Ophthal (Chicago) 70:500-507, 1963.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Mar 1, 1964

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