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Bacteriological Aspects of Blepharitis

Bacteriological Aspects of Blepharitis Abstract Blepharitis represents one of the more common lid disorders. Classification of this disease into 2 distinct entities has been well accepted.1 Seborrheic blepharitis, in which a budding yeast, Pityrosporum ovale, is frequently associated, is statistically the more common. In the second group the ulcerative type, Staphylococcus aureus, has been incriminated.2 Therapy, therefore, has been related to the diagnostic classification to which a given patient is assigned. It is the purpose of this communication to reassess the relationship between lid flora and blepharitis and to compare the clinical and bacteriological results obtained from steroid, antibiotic, and keratolytic agents. Materials and Methods Patients were obtained from the private and clinic services of the New York Hospital-Cornell Medical Center. Thirty-seven consecutive patients with blepharitis were studied. In 30 of these, bacteriological studies were complete and follow-up adequately detailed to permit reporting. Two patients with more esoteric causes for blepharitis (fungal and References 1. Kindly supplied as Blef-Dome Ointment by Dome Chemicals Inc., New York 23. 2. Kindly supplied as Hydro-Cortone Acetate Ointment by Merck Sharp & Dohme, Philadelphia. 3. Kindly supplied as Neosporin Ointment by Burroughs-Wellcome & Co., Tuckahoe, N.Y. 4. Thygeson, P.: Etiology and Treatment of Blepharitis , Arch. Ophthal. 36:445, 1946.Crossref 5. Thygeson, P., and Vaughan, D. G.: Seborrheic Blepharitis , Trans. Amer. Ophthal. Soc. 52: 173, 1954. 6. Hickey, C. S.: Pityrosporum Ovale: A Cause of Blepharitis , J. Maine Med. Ass. 41:135, 1950. 7. Bahn, G. C.: The Treatment of Seborrheic Blepharitis , Southern Med. J. 47:749, 1954.Crossref 8. Lavyel, A.: Selsunef Ointment to Treat Squamous Blepharitis , Amer. J. Ophthal. 49:820, 1960. 9. Wong, A. S.; Fasanella, R. M.; Haley, L. D.; Marshall, C. L., and Krehl, W. A.: Selenium (Selsun) in the Treatment of Marginal Blepharitis , A.M.A. Arch. Ophthal. 55:246, 1956.Crossref 10. Quintieri, C.: Treatment of Squamous Blepharitis by Selenium Sulphide , Boll. Oculist. 34:687, 1955. 11. Ainslie, D.: The Treatment of Blepharitis , Brit. Med. J. 4731:582, 1951.Crossref 12. Repaski, R.: Lysis of Gram-Negative Organisms and the Role of Versene , Biochim. Biophys. Acta 30:225, 1958.Crossref 13. MacGregor, D. R., and Elliker, P. R.: A Comparison of Some Properties of Strains of Pseudomonas Aeruginosa Sensitive and Resistant to Quaternary Ammonium Compounds , Canad. J. Microbiol. 4:499, 1958.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Bacteriological Aspects of Blepharitis

GALIN, MILES A.
Archives of Ophthalmology , Volume 67 (6) – Jun 1, 1962
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References (10)

Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1962.00960020746008
Publisher site
See Article on Publisher Site

Abstract

Abstract Blepharitis represents one of the more common lid disorders. Classification of this disease into 2 distinct entities has been well accepted.1 Seborrheic blepharitis, in which a budding yeast, Pityrosporum ovale, is frequently associated, is statistically the more common. In the second group the ulcerative type, Staphylococcus aureus, has been incriminated.2 Therapy, therefore, has been related to the diagnostic classification to which a given patient is assigned. It is the purpose of this communication to reassess the relationship between lid flora and blepharitis and to compare the clinical and bacteriological results obtained from steroid, antibiotic, and keratolytic agents. Materials and Methods Patients were obtained from the private and clinic services of the New York Hospital-Cornell Medical Center. Thirty-seven consecutive patients with blepharitis were studied. In 30 of these, bacteriological studies were complete and follow-up adequately detailed to permit reporting. Two patients with more esoteric causes for blepharitis (fungal and References 1. Kindly supplied as Blef-Dome Ointment by Dome Chemicals Inc., New York 23. 2. Kindly supplied as Hydro-Cortone Acetate Ointment by Merck Sharp & Dohme, Philadelphia. 3. Kindly supplied as Neosporin Ointment by Burroughs-Wellcome & Co., Tuckahoe, N.Y. 4. Thygeson, P.: Etiology and Treatment of Blepharitis , Arch. Ophthal. 36:445, 1946.Crossref 5. Thygeson, P., and Vaughan, D. G.: Seborrheic Blepharitis , Trans. Amer. Ophthal. Soc. 52: 173, 1954. 6. Hickey, C. S.: Pityrosporum Ovale: A Cause of Blepharitis , J. Maine Med. Ass. 41:135, 1950. 7. Bahn, G. C.: The Treatment of Seborrheic Blepharitis , Southern Med. J. 47:749, 1954.Crossref 8. Lavyel, A.: Selsunef Ointment to Treat Squamous Blepharitis , Amer. J. Ophthal. 49:820, 1960. 9. Wong, A. S.; Fasanella, R. M.; Haley, L. D.; Marshall, C. L., and Krehl, W. A.: Selenium (Selsun) in the Treatment of Marginal Blepharitis , A.M.A. Arch. Ophthal. 55:246, 1956.Crossref 10. Quintieri, C.: Treatment of Squamous Blepharitis by Selenium Sulphide , Boll. Oculist. 34:687, 1955. 11. Ainslie, D.: The Treatment of Blepharitis , Brit. Med. J. 4731:582, 1951.Crossref 12. Repaski, R.: Lysis of Gram-Negative Organisms and the Role of Versene , Biochim. Biophys. Acta 30:225, 1958.Crossref 13. MacGregor, D. R., and Elliker, P. R.: A Comparison of Some Properties of Strains of Pseudomonas Aeruginosa Sensitive and Resistant to Quaternary Ammonium Compounds , Canad. J. Microbiol. 4:499, 1958.Crossref

Journal

Archives of Ophthalmology – American Medical Association

Published: Jun 1, 1962

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