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Transient Myopia and Retinal Edema During Hydrochlorothiazide (Hydrodiuril) Therapy

Transient Myopia and Retinal Edema During Hydrochlorothiazide (Hydrodiuril) Therapy Abstract This is a report of a case of transient myopia associated with perimacular edema apparently secondary to the use of a total of 100 mg. of hydrochlorothiazide (Hydrodiuril). Hydrochlorothiazide is an oral, nonmercurial d i u r e t i c-antihypertensive agent. It is defined chemically as 6-chloro-7-sulfamyl-3,4-dihydro-1,2,4- benzothiadiazine-1,1-dioxide. Report of Case A 21-year-old white primiparous woman whose estimated date of confinement was July 24, 1959, and whose past medical history and systemic review were noncontributory, was seen by her obstetrician on July 7, 1959, for a routine examination. Physical Examination. —Her temperature was 98F, weight 138 lb. (125 lb. before pregnancy), and blood pressure 100/70. There was some swelling of the lower extremities. Laboratory Data. —The urine revealed no albumin or sugar. Her previously determined serology was negative and blood type O Rh positive.Because of the swelling of her legs, she was advised to restrict References 1. Bach, M.: Transient Myopia After Use of Acetazolamide (Diamox) , A.M.A. Arch. Ophth. 55:546-547 ( (April) ) 1956.Crossref 2. Binder, S., and Steels, W., Sr.: Acute Transient Myopia Associated with Use of Acetazolamide (Diamox) , J.A.M.A. 165:154-155 ( (Sept. 14) ) 1957.Crossref 3. Christiansson, J.: Transient Myopia After the Administration of Diamox , Acta ophth. 36:356-357, 1958.Crossref 4. Halpern, A., and Kulvin, M.: Transient Myopia During Treatment with Carbonic Anhydrase Inhibitors , Am. J. Ophth. 48:534-535 ( (Oct.) ) 1959. 5. Kroning, E.: Transient Myopia Following the Use of Acetazolamide , Acta ophth. 35:478-484, 1957.Crossref 6. Stern, J. J.: Transient Myopia in a Case of Dermatitis Treated with Corticotropin , A.M.A. Arch. Ophth. 54:762 ( (Nov.) ) 1955.Crossref 7. Grossman, E., and Hanley, W.: Transient Myopia During Treatment for Hypertension with Autonomic Blocking Agents , A.M.A. Arch. Ophth. 63:853-855 ( (May) ) 1960.Crossref 8. Muirhead, J., and Scheie, H.: Transient Myopia After Acetazolamide , A.M.A. Arch. Ophth. 63:315-318 ( (Feb.) ) 1960.Crossref 9. Mattsson, R.: Transient Myopia Following the Use of Sulphonamides , Acta ophth. 30:385-398, 1952.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Transient Myopia and Retinal Edema During Hydrochlorothiazide (Hydrodiuril) Therapy

BEASLEY, FRANK J.
Archives of Ophthalmology , Volume 65 (2) – Feb 1, 1961
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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1961.01840020214009
Publisher site
See Article on Publisher Site

Abstract

Abstract This is a report of a case of transient myopia associated with perimacular edema apparently secondary to the use of a total of 100 mg. of hydrochlorothiazide (Hydrodiuril). Hydrochlorothiazide is an oral, nonmercurial d i u r e t i c-antihypertensive agent. It is defined chemically as 6-chloro-7-sulfamyl-3,4-dihydro-1,2,4- benzothiadiazine-1,1-dioxide. Report of Case A 21-year-old white primiparous woman whose estimated date of confinement was July 24, 1959, and whose past medical history and systemic review were noncontributory, was seen by her obstetrician on July 7, 1959, for a routine examination. Physical Examination. —Her temperature was 98F, weight 138 lb. (125 lb. before pregnancy), and blood pressure 100/70. There was some swelling of the lower extremities. Laboratory Data. —The urine revealed no albumin or sugar. Her previously determined serology was negative and blood type O Rh positive.Because of the swelling of her legs, she was advised to restrict References 1. Bach, M.: Transient Myopia After Use of Acetazolamide (Diamox) , A.M.A. Arch. Ophth. 55:546-547 ( (April) ) 1956.Crossref 2. Binder, S., and Steels, W., Sr.: Acute Transient Myopia Associated with Use of Acetazolamide (Diamox) , J.A.M.A. 165:154-155 ( (Sept. 14) ) 1957.Crossref 3. Christiansson, J.: Transient Myopia After the Administration of Diamox , Acta ophth. 36:356-357, 1958.Crossref 4. Halpern, A., and Kulvin, M.: Transient Myopia During Treatment with Carbonic Anhydrase Inhibitors , Am. J. Ophth. 48:534-535 ( (Oct.) ) 1959. 5. Kroning, E.: Transient Myopia Following the Use of Acetazolamide , Acta ophth. 35:478-484, 1957.Crossref 6. Stern, J. J.: Transient Myopia in a Case of Dermatitis Treated with Corticotropin , A.M.A. Arch. Ophth. 54:762 ( (Nov.) ) 1955.Crossref 7. Grossman, E., and Hanley, W.: Transient Myopia During Treatment for Hypertension with Autonomic Blocking Agents , A.M.A. Arch. Ophth. 63:853-855 ( (May) ) 1960.Crossref 8. Muirhead, J., and Scheie, H.: Transient Myopia After Acetazolamide , A.M.A. Arch. Ophth. 63:315-318 ( (Feb.) ) 1960.Crossref 9. Mattsson, R.: Transient Myopia Following the Use of Sulphonamides , Acta ophth. 30:385-398, 1952.Crossref

Journal

Archives of Ophthalmology – American Medical Association

Published: Feb 1, 1961

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