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Conjunctivitis Due to Neomycin Sensitivity

Conjunctivitis Due to Neomycin Sensitivity Abstract Neomycin is a valuable antibiotic widely used in the topical treatment of infections of the conjunctiva. Until recently neomycin was considered a very rare sensitizer. This, however, is not correct, as neomycin contact dermatitis has been reported by several authors.1-5 But neomycin contact dermatitis often is masked and overlooked by the physician.1-3 This also seems to be true when neomycin sensitivity involves the conjunctiva. For this reason, the following four cases are reported. Report of Cases Case 1. —A white man, age 83, was referred by an ophthalmologist because of a conjunctivitis and contact dermatitis of the eyelids. He had used Neo-Cortef eyedrops (hydrocortisone acetate and neomycin sulfate) several months previously because of a conjunctivitis. A few months later, when his difficulty returned, he again used the same eyedrops. This time the conjunctivitis became worse and a dermatitis of the lids developed.Neomycin sensitivity was suspected.Patch tests References 1. Peculiarities of neomycin sensitivity have been discussed by one of us (S. E.) elsewhere.1-3 2. Epstein, S.: Contact Dermatitis from Neomycin , J. A. M. A. 160:1355 ( (April 4) ) 1956.Crossref 3. Epstein, S.: Contact Dermatitis due to Dermal Delayed (Tuberculin-Type) Sensitivity , Dermatologica 113:191-201 ( (Nov.) ) 1956.Crossref 4. Epstein, S.: Dermal Contact Dermatitis from Neomycin: Report of 40 Cases , Ann. Allergy 16: 268-280 ( (May-June) ) 1958. 5. Hjorth, N.: Personal communication to the authors. 6. Pirilä, V., and Wallenius, T.: Über die ekzematöse Sensibilizierung gegen Neomycin und Bacitracin , Hautarzt 8:518-519 ( (Nov.) ) 1957. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Ophthalmology American Medical Association

Conjunctivitis Due to Neomycin Sensitivity

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1958 American Medical Association. All Rights Reserved.
ISSN
0096-6339
DOI
10.1001/archopht.1958.00940081020004
Publisher site
See Article on Publisher Site

Abstract

Abstract Neomycin is a valuable antibiotic widely used in the topical treatment of infections of the conjunctiva. Until recently neomycin was considered a very rare sensitizer. This, however, is not correct, as neomycin contact dermatitis has been reported by several authors.1-5 But neomycin contact dermatitis often is masked and overlooked by the physician.1-3 This also seems to be true when neomycin sensitivity involves the conjunctiva. For this reason, the following four cases are reported. Report of Cases Case 1. —A white man, age 83, was referred by an ophthalmologist because of a conjunctivitis and contact dermatitis of the eyelids. He had used Neo-Cortef eyedrops (hydrocortisone acetate and neomycin sulfate) several months previously because of a conjunctivitis. A few months later, when his difficulty returned, he again used the same eyedrops. This time the conjunctivitis became worse and a dermatitis of the lids developed.Neomycin sensitivity was suspected.Patch tests References 1. Peculiarities of neomycin sensitivity have been discussed by one of us (S. E.) elsewhere.1-3 2. Epstein, S.: Contact Dermatitis from Neomycin , J. A. M. A. 160:1355 ( (April 4) ) 1956.Crossref 3. Epstein, S.: Contact Dermatitis due to Dermal Delayed (Tuberculin-Type) Sensitivity , Dermatologica 113:191-201 ( (Nov.) ) 1956.Crossref 4. Epstein, S.: Dermal Contact Dermatitis from Neomycin: Report of 40 Cases , Ann. Allergy 16: 268-280 ( (May-June) ) 1958. 5. Hjorth, N.: Personal communication to the authors. 6. Pirilä, V., and Wallenius, T.: Über die ekzematöse Sensibilizierung gegen Neomycin und Bacitracin , Hautarzt 8:518-519 ( (Nov.) ) 1957.

Journal

A.M.A. Archives of Ophthalmology – American Medical Association

Published: Dec 1, 1958

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