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J. Friedenwald, D. Rytel (1955)
Contribution to the histopathology of cataract.A.M.A. archives of ophthalmology, 53 6
L. Sallmann, L. Caravaggio, Carmen Munoz, A. Drungis (1957)
Species differences in the radiosensitivity of the lens.American journal of ophthalmology, 43 5
Kok-van Cc (1952)
Lens changes in alloxan diabetes.Ophthalmologica, 123
G. Bounds, R. Janes, P. Leinfelder (1955)
Cataracts induced by alloxan diabetes in rats and rabbits; experimental studies.A.M.A. archives of ophthalmology, 54 4
G. W. Bounds , R. G. Janes (1955)
Cataracts Induced by Alloxan Diabetes in Rats and Rabbits: Experimental StudiesA.M. A. Arch. Ophth., 54
Kok-van Cc, Cohen Em (1950)
The occurrence of cataract in alloxan diabetic rats.Acta physiologica et pharmacologica Neerlandica, 1
J. S. Friedenwald (1955)
Contribution to the Histopathology of CataractA. M. A. Arch. Ophth., 53
E. M. Cohen (1953)
Insulin Against Alloxan Diabetic Cataract in RatsActa physiol. et pharmacol. neerl., 3
J. W. Patterson (1955)
Cataractogenic SugarsArch. Biochem., 58
J. Patterson (1952)
Development of diabetic cataracts.American journal of ophthalmology, 35 5 2
D. Naidoff, I. Pincus, A. Town, M. Scott (1953)
Cataracts in alloxan diabetic rabbits.A.M.A. archives of ophthalmology, 50 2
P. Mandel , M. L. Schmitt (1956)
�tude sur la consommation d'acide pyruvique du cristallin au cours du diab�te exp�rimentalBull. Soc. chim. biol., 38
M. Somogyi (1945)
A NEW REAGENT FOR THE DETERMINATION OF SUGARSJournal of Biological Chemistry, 160
J. Babel (1953)
Die durch Alloxan hervorgerufene Diabeteskatarakt: Vergleichende Studie experimenteller Kataraktbildung infolge allgemeiner Stoffwechselst�rungenvon Graefes Arch. Ophth., 153
J. Patterson (1952)
Effect of lowered blood sugar in development of diabetic cataracts.The American journal of physiology, 172 1
J. Patterson (1956)
Diabetic Cataracts: A Review of Experimental StudiesDiabetes, 5
S. Klebanoff, A. Greenbaum (1954)
The effect of pH on the diabetogenic action of alloxan.The Journal of endocrinology, 11 4
J. Patterson (1954)
Effect of Partial Starvation on Development of Diabetic Cataracts.∗Proceedings of the Society for Experimental Biology and Medicine, 87
C. Velzeboer (1952)
Crystalline lens changes in alloxan diabetesNederlands Tijdschrift voor Geneeskunde, 96
J. Patterson (1955)
Effect of blood supply on the development of cataracts.The American journal of physiology, 180 3
N. Nelson (1944)
A PHOTOMETRIC ADAPTATION OF THE SOMOGYI METHOD FOR THE DETERMINATION OF GLUCOSEJournal of Biological Chemistry, 153
P. Mandel , C. A. Quaranta (1956)
�tude sur l'activit� ad�nosinetriphosphatasique du cristallin au cours du diab�te exp�rimentalBull. Soc. chim. biol., 38
R. G. Janes , G. W. Bounds (1952)
Ocular Complications in the Rat Made Diabetic with AlloxanA. M. A. Arch. Ophth., 48
R. Janes, G. Bounds, P. Leinfelder (1952)
Ocular complications in the rat made diabetic with alloxan.A.M.A. archives of ophthalmology, 48 4
C. Bailey, O. Bailey, R. Leech (1944)
Alloxan diabetes with diabetic complications.The New England Journal of Medicine, 230
D. Naidoff , I. J. Pincus, A. W. Town (1955)
Cataracts in Alloxan Diabetic RabbitsAm. J. Ophth., 39
J. Bellows, D. Shoch (1950)
Alloxan diabetes and the lens.American journal of ophthalmology, 33 10
J. W. Patterson (1955)
Effect of High Fat, Fructose, and Casein Diet on Diabetic CataractsProc. Soc. Exper. Biol. & Med., 90
P. Mandel (1955)
�tude sur l'activit� hexokinasique de cristallins de rats trait�s par l'alloxaneBull. Soc. chim. biol., 37
L. von Sallmann (1957)
XIII Jackson Memorial Lecture: The Lens Epithelium in the Pathogenesis of CataractTr. Am. Acad. Ophth., 61
Abstract Previous work on experimental cataract carried out in these laboratories dealt with morphological aspects of the problem and emphasized the sequence of epithelial and fiber pathology as well as the correlation of the histological and cytological changes with biomicroscopic observations in four types of experimental cataract. Experiments on alloxan-diabetic animals were not included in this work in view of the difference in the approach in the alloxan series. Modification comprised low-magnification viewing under the dissecting microscope and observation of the effects of the cataractogenic agent when it had been introduced into the vitreous chamber of the rabbit. Material and Experimental Procedure The rat served as experimental animal in the main part of the study. The males of 46 litters of Sprague-Dawley rats (five animals per litter) from the NIH stock were from 23 to 25 days old at the onset of the experiment. The material was divided into five groups References 1. Nelson, N.: A Photometric Adaptation of the Somogyi Method for the Determination of Glucose , J. Biol. Chem. 153:375, 1944. 2. Somogyi, M.: A New Reagent for the Determination of Sugars , J. Biol. Chem. 160:61, 1945. 3. Klebanoff, S. J., and Greenbaum, A. L.: The Effect of pH on the Diabetogenic Action of Alloxan , J. Endocrinol. 11:314, 1954.Crossref 4. von Sallmann, L.; Caravaggio, L.; Munoz, C. M., and Drungis, A.: Species Differences in the Radiosensitivity of the Lens , Am. J. Ophth. 43:693-704, 1957. 5. von Sallmann, L.: XIII Jackson Memorial Lecture: The Lens Epithelium in the Pathogenesis of Cataract , Tr. Am. Acad. Ophth. 61:7, 1957. 6. Bailey, C. C.; Bailey, O. T., and Leech, R. S.: Alloxan Diabetes with Diabetic Complications , New England J. Med. 230:533, 1944.Crossref 7. Bellows, J. E., and Shoch, D. E.: Alloxan Diabetes and the Lens , Am. J. Ophth. 33:1555, 1950. 8. Babel, J.: Die durch Alloxan hervorgerufene Diabeteskatarakt: Vergleichende Studie experimenteller Kataraktbildung infolge allgemeiner Stoffwechselstörungen , von Graefes Arch. Ophth. 153:520, 1953.Crossref 9. Friedenwald, J. S., and Rytel, D.: Contribution to the Histopathology of Cataract , A. M. A. Arch. Ophth. 53:825, 1955.Crossref 10. Bounds, G. W., Jr.; Janes, R. G., and Leinfelder, P. J.: Cataracts Induced by Alloxan Diabetes in Rats and Rabbits: Experimental Studies , A.M. A. Arch. Ophth. 54:564, 1955.Crossref 11. Kok-Van Alphen, C. C., and Cohen, E. M.: The Occurrence of Cataract in Alloxan Diabetic Rats , Acta physiol. et pharmacol. neerl. 1:400, 1950. 12. Janes, R. G.; Bounds, G. W., Jr., and Leinfelder, P. J.: Ocular Complications in the Rat Made Diabetic with Alloxan , A. M. A. Arch. Ophth. 48:414, 1952.Crossref 13. Kok-Van Alphen, C. C.: Crystalline Lens Changes in Alloxan Diabetes , Nederl. tijdschr. geneesk. 96:59, 1952 14. Ophthalmologica 123:186, 1952. 15. Cohen, E. M., and Kok-Van Alphen, C. C.: Insulin Against Alloxan Diabetic Cataract in Rats , Acta physiol. et pharmacol. neerl. 3:81, 1953. 16. Naidoff, D.; Pincus, I. J.; Town, A. W., and Scott, M. E.: Cataracts in Alloxan Diabetic Rabbits , Am. J. Ophth. 39:510 (April, (Pt. 1) ) 1955. 17. Patterson, J. W.: Development of Diabetic Cataracts , Am. J. Ophth. 35:69 (May, (Pt. 2) ) 1952. 18. Patterson, J. W.: Effect of Lowered Blood Sugar on Development of Diabetic Cataracts , Am. J. Physiol. 172:77, 1953. 19. Patterson, J. W.: Effect of Partial Starvation on Development of Diabetic Cataract , Proc. Soc. Exper. Biol. & Med. 87:395, 1954. 20. Patterson, J. W.: Effect of Blood Supply on the Development of Cataracts , Am. J. Physiol. 180:495, 1955. 21. Patterson, J. W.: Effect of High Fat, Fructose, and Casein Diet on Diabetic Cataracts , Proc. Soc. Exper. Biol. & Med. 90:706, 1955. 22. Patterson, J. W.: Cataractogenic Sugars , Arch. Biochem. 58:24, 1955. 23. Patterson, J. W.: Diabetic Cataracts: A Review of Experimental Studies , Diabetes 5:93, 1956. 24. Mandel, P., and Schmitt, M. L.: Étude sur l'activité hexokinasique de cristallins de rats traités par l'alloxane , Bull. Soc. chim. biol. 37: 847, 1955. 25. Mandel, P.; Quaranta, C. A., and Schmitt, M. L.: Étude sur l'activité adénosinetriphosphatasique du cristallin au cours du diabète expérimental , Bull. Soc. chim. biol. 38:139, 1956. 26. Mandel, P.; Schmitt, M. L., and Quaranta, C. A.: Étude sur la consommation d'acide pyruvique du cristallin au cours du diabéte expèrimental , Bull. Soc. chim. biol. 38:441, 1956.
A.M.A. Archives of Ophthalmology – American Medical Association
Published: Jan 1, 1958
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