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CLINICAL AND AUTOPSY FINDINGS IN EARLY RETROLENTAL FIBROPLASIA: Report of a Case

CLINICAL AND AUTOPSY FINDINGS IN EARLY RETROLENTAL FIBROPLASIA: Report of a Case Abstract FEW REPORTS of the pathologic changes in early cases of retrolental fibroplasia have appeared in the literature. Heath,1 in 1950, classified retrolental fibroplasia as a syndrome and described the pathologic findings in the early and later stages of retrolental fibroplasia in premature infants. He described the primary disease as "an edematous, hemorrhagic and proliferative process associated with hamartomatous neovascular tissue in the retina, a process best described as a retinopathy of premature birth." Heath defined "hamartoma" as an accumulation of vascular tissue, normal in location but excessive in amount, and without the property of malignant growth. Reese,2 in 1951, described the autopsy observations in a case of early retrolental fibroplasia. Sections of these eyes showed "angiomatous tissue extending from the retina into the vitreous, particularly in the periphery around the base of the vitreous." Reese stated that the outstanding feature is the angioplastic process in the vitreous and References 1. Heath, P.: Retrolental Fibroplasia as a Syndrome: Pathogenesis and Classifications , Arch. Ophth. 44:245-274 ( (Aug.) ) 1950.Crossref 2. Reese, A. B., and Blodi, F. C.: Retrolental Fibroplasia , Am. J. Ophth. 34:1-24 ( (Jan.) ) 1951. 3. Friedenwald, J. S.; Owens, W. C., and Owens, E. U.: Read at the Eighty-Seventh Annual Meeting of the American Ophthalmological Society, June 7-9, 1951, White Sulphur Springs, W. Va., to be published. 4. Scheie, H. G.; Tyner, G. S.; Buessler, J. A., and Alfano, J. E.: Adrenocorticotropic Hormone (ACTH) and Cortisone in Ophthalmology , A. M. A. Arch. Ophth. 45:301-316 ( (March) ) 1951.Crossref 5. The findings were similar in the two eyes. Figures 1 to 6, from sections of the left eye, were used because the photographs were the clearest. Figures 7 and 8 are of the right eye. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Ophthalmology American Medical Association

CLINICAL AND AUTOPSY FINDINGS IN EARLY RETROLENTAL FIBROPLASIA: Report of a Case

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References (3)

Publisher
American Medical Association
Copyright
Copyright © 1951 American Medical Association. All Rights Reserved.
ISSN
0096-6339
DOI
10.1001/archopht.1951.01700020661005
Publisher site
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Abstract

Abstract FEW REPORTS of the pathologic changes in early cases of retrolental fibroplasia have appeared in the literature. Heath,1 in 1950, classified retrolental fibroplasia as a syndrome and described the pathologic findings in the early and later stages of retrolental fibroplasia in premature infants. He described the primary disease as "an edematous, hemorrhagic and proliferative process associated with hamartomatous neovascular tissue in the retina, a process best described as a retinopathy of premature birth." Heath defined "hamartoma" as an accumulation of vascular tissue, normal in location but excessive in amount, and without the property of malignant growth. Reese,2 in 1951, described the autopsy observations in a case of early retrolental fibroplasia. Sections of these eyes showed "angiomatous tissue extending from the retina into the vitreous, particularly in the periphery around the base of the vitreous." Reese stated that the outstanding feature is the angioplastic process in the vitreous and References 1. Heath, P.: Retrolental Fibroplasia as a Syndrome: Pathogenesis and Classifications , Arch. Ophth. 44:245-274 ( (Aug.) ) 1950.Crossref 2. Reese, A. B., and Blodi, F. C.: Retrolental Fibroplasia , Am. J. Ophth. 34:1-24 ( (Jan.) ) 1951. 3. Friedenwald, J. S.; Owens, W. C., and Owens, E. U.: Read at the Eighty-Seventh Annual Meeting of the American Ophthalmological Society, June 7-9, 1951, White Sulphur Springs, W. Va., to be published. 4. Scheie, H. G.; Tyner, G. S.; Buessler, J. A., and Alfano, J. E.: Adrenocorticotropic Hormone (ACTH) and Cortisone in Ophthalmology , A. M. A. Arch. Ophth. 45:301-316 ( (March) ) 1951.Crossref 5. The findings were similar in the two eyes. Figures 1 to 6, from sections of the left eye, were used because the photographs were the clearest. Figures 7 and 8 are of the right eye.

Journal

A.M.A. Archives of Ophthalmology – American Medical Association

Published: Dec 1, 1951

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